Depression & Insomnia & Major Cause of Death is Heart Failure: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Depression, Insomnia, Major Cause of Death is Heart Failure,

Negated

None

Unsure

None

Possible Causes

Chronic Kidney Insufficiency

[…] alert cramps and twitches numbness in your limbs weakness fatigue bad breath skin that’s darker or lighter than usual bone pain excessive thirst bleeding and bruising easily insomnia [healthline.com]

Early detection can help prevent the progression of kidney disease to kidney failure. Heart disease is the major cause of death for all people with CKD. [kidney.org]

Barbieri, MD April 2, 2019 Journal of Clinical Outcomes Management March 14, 2019 ‘Difficult’ discussions reduced anxiety, depression in life-limiting cancer patients March [jcomjournal.com]

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Obstructive Sleep Apnea

[…] with insomnia and OSA symptoms. [ncbi.nlm.nih.gov]

heart failure. [ncbi.nlm.nih.gov]

On the other hand, sleep problems and specifically OSA are rarely assessed on a regular basis in patients with a depressive disorder. [ncbi.nlm.nih.gov]

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Hypertension

BACKGROUND: Hypertension and insomnia are common diseases in the elderly. [ncbi.nlm.nih.gov]

High blood pressure is a major contributing risk factor to heart failure, heart attack, stroke, and chronic kidney disease. [doi.org]

This approach can be helpful for clinical diagnosis of depression, but further studies are needed to verify the role of these candidate markers for depression diagnosis. [ncbi.nlm.nih.gov]

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Congestive Heart Failure

Features due to right heart failure: Headache, insomnia and restlessness: These symptoms occur because of cerebral congestion. [symptoma.com]

Major secondary outcomes were all cause mortality during the trial period, all reported cardiovascular deaths, admission to hospital for heart failure, cardiovascular admission [doi.org]

Radu.Saveanu@osumc.edu Abstract Depression is an all too common occurrence in heart failure patients. [ncbi.nlm.nih.gov]

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Heart Failure

[…] are often assumed principally to suffer from fatigue and dyspnea, a majority have pain, and depression is extremely common. 11 Other sources of suffering include edema, insomnia [doi.org]

Major secondary outcomes were all cause mortality during the trial period, all reported cardiovascular deaths, admission to hospital for heart failure, cardiovascular admission [doi.org]

Changes in central neurohumoral regulation systems or diminished central perfusion might impair cognitive capacity and trigger a latent vulnerability to depressive disorders [doi.org]

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Alzheimer Disease

[…] experience, and continuing education, as well as knowledge of AD disease and treatment expectations, adverse effects (AEs) of donepezil, and self-care recommendations for insomnia [ncbi.nlm.nih.gov]

In other words, this is a major medical issue which is becoming an increasing cause of death in USA and all over the world second only to heart failure. [symptoma.com]

Relative to those without depression, "amyloid-associated depression," defined by presence of depression and a high plasma Abeta(40):Abeta(42) ratio, was associated with greater [ncbi.nlm.nih.gov]

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Anorexia Nervosa

[…] including depression and anxiety, are often reported by individuals who are underweight and can manifest in a variety of ways such as social withdrawal, irritability, and insomnia [mountsinai.org]

The most frequent causes of death associated with anorexia are starvation, electrolyte imbalance, heart failure, and suicide. [healthofchildren.com]

We showed, that despite our positive clinical experiences with rTMS therapy in depression and anxiety, the treatment of AN and comorbid depressive disorder with anxious distress [ncbi.nlm.nih.gov]

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Anorexia

Several more severe medical complications for anorexia include: Irregular heartbeats Low blood sugar Loss of bone mass Kidney and liver damage Osteoporosis Insomnia Anemia [mccallumplace.com]

The most frequent causes of death associated with anorexia are starvation, electrolyte imbalance, heart failure, and suicide. [healthofchildren.com]

disorder, or bipolar disorder are believed to have an increased risk of eventually displaying signs and symptoms associated with anorexia nervosa. [centerforhopeofthesierras.com]

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Myocardial Infarction

Insomnia and the risk of acute myocardial infarction. Circulation 2011 ; 124 : 2073 -81. Liu Y, Tanaka H, Fukuoka Heart Study Group. [doi.org]

MD Scope and Significance C oronary artery disease is a major cause of morbidity and mortality as a result of acute myocardial infarction (MI) or subsequent heart failure [ncbi.nlm.nih.gov]

The Beck Depression Inventory-II (BDI-II) was used to measure depressive symptoms, which were analyzed as overall score, and as separate somatic and cognitive depressive symptom [dx.doi.org]

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Eating Disorder

In this presentation, the case of a 46-year-old female who developed sleep related eating disorder when she was treated with zolpidem for insomnia is reported. [ncbi.nlm.nih.gov]

Some of the health consequences of bulimia nervosa include: Electrolyte imbalances that can lead to irregular heartbeats and possibly heart failure and death. [web.archive.org]

The studies confirm the prominence of depressive symptoms and depressive disorders in eating disorders. [ncbi.nlm.nih.gov]

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Fabry Disease

[…] and to pool information regarding the disease, the diagnosis procedure, available treatments and the impact it could have on the life of someone diagnosed with insomnia. [idorsia.com]

Mortality/Morbidity Before the advent of enzyme replacement therapy, renal failure secondary to uremia and hypertension was the major cause of death for men with angiokeratoma [dermaamin.com]

[…] of GL-3 and its derivative, lyso-GL-3, results in symptoms that include characteristic skin lesions (angiokeratomas), decreased sweating (hypohidrosis), chronic fatigue, depression [sema4genomics.com]

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Systemic Scleroderma

Lyme clients can also experience insomnia, hormone imbalances and weight gain : many of the same symptoms we see in neurotoxic illness. [drpompa.com]

major organ failure (heart, lung, kidney), defined as left ventricular ejection fraction less than 30% by echocardiography (or multiple-gated acquisition scan), resting arterial [doi.org]

[…] disability, quality of life and depressive symptoms. [ncbi.nlm.nih.gov]

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Kidney Failure

This could lead to symptoms such as nausea, vomiting, fatigue, decreased appetite, insomnia, dry and itchy skin, muscle cramps, urine reduction, puffy eyelids, fluid in the [bumrungrad.com]

Early detection can help prevent the progression of kidney disease to kidney failure. Heart disease is the major cause of death for all people with CKD. [kidney.org]

OUTCOMES: Zarit Burden Inventory (ZBI) and Hospital Anxiety and Depression Scale (HADS) in caregivers and McGill Quality of Life scores in patients of both groups were compared [ncbi.nlm.nih.gov]

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Bulimia Nervosa

She suffered from adverse effects including headaches, tachycardia, anxiety, insomnia, and, finally, grand mal seizures. [ncbi.nlm.nih.gov]

Some of the health consequences of bulimia nervosa include: Electrolyte imbalances that can lead to irregular heartbeats and possibly heart failure and death. [web.archive.org]

Seventy percent of the patients had, at some time during their lives, met Research Diagnostic Criteria (RDC) for an episode of major depression and 88% had met RDC at some [ncbi.nlm.nih.gov]

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Angina Pectoris

Choppy or Wiry and tight Treatment Principle Invigorate the Blood Relieve Stasis Stop pain Herb Formulas Points Clinical Manifestations Palpitations Anxiety Irritability Insomnia [americandragon.com]

Less common causes include major blood loss, lack of oxygen, very low potassium, heart failure, and intense physical exercise. [en.wikipedia.org]

After additional adjustment for anxiety, depression was no longer associated with higher mortality. [ncbi.nlm.nih.gov]

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Stroke

A study published in May 2018 has found evidence that insomnia may be a long-term side effect for stroke survivors, indicating that treating insomnia may be an important part [everydayhealth.com]

Major coronary events were defined as the first occurrence of nonfatal myocardial infarction or coronary death (including death from heart failure and sudden or unexpected [doi.org]

Primary analyses were the prevalence of diagnosable depressive disorder at the end of treatment. [ncbi.nlm.nih.gov]

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SHORT Syndrome

Short sleeping also is different from insomnia. People with insomnia have a hard time falling asleep or staying asleep. The overall quality of their sleep may be poor. [sleepeducation.org]

Cardiovascular mortality was defined as death caused by heart failure, arrhythmia, myocardial infarction, cerebrovascular disease, pulmonary embolism or sudden cardiac death [revportcardiol.org]

Tooth eruption delay - Similarly to ocular depression, delay in the eruption of teeth is confirmed in almost every patient suffering from SHORT syndrome. [symptoma.com]

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Low Back Pain

This article focuses on insomnia and presents a treatment algorithm for managing insomnia in older adults, along with a representative clinical case. [ncbi.nlm.nih.gov]

[…] for heart failure. [ncbi.nlm.nih.gov]

This article focuses on depression. [ncbi.nlm.nih.gov]

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Coronary Atherosclerosis

[…] and 0.6 percent), myalgia (1.2 percent and 2.4 percent), constipation (1.2 percent and 1.8 percent), increased aspartate aminotransferase (0 percent and 1.2 percent) and insomnia [pfizer.it]

or hospitalization for heart failure. [ncbi.nlm.nih.gov]

We therefore refer to the exposure in this paper as major depression as opposed to the DSM-IV category of major depressive disorder (MDD). [ncbi.nlm.nih.gov]

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Diabetes Mellitus

These side effects are: Insomnia Loss of appetite Constipation Weight loss Short temper Stains and bruises on the skin These effects occur due to people taking the same kratom [idsoc.org]

The reductions in risk of CV death, all-cause mortality, 3-point major adverse cardiac events, hospitalization for heart failure (HHF), and HHF or CV death with empagliflozin [acc.org]

Overall mental health, depression, and anxiety were measured using the General Health Questionnaire (GHQ-28), Hamilton Depression Rating Scale (HDRS), and Hamilton Anxiety [ncbi.nlm.nih.gov]

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Sarcoidosis

[…] obesity. 42 In addition to the above abnormalities, other manifestations attributed to hypothalamic sarcoidosis include marked somnolence, often preceded or followed by insomnia [doi.org]

Cardiac sarcoidosis has the potential to lead to heart failure and ventricular arrhythmias ( 49 ) with sudden cardiac death as the major cause of mortality among patients [doi.org]

Beck Depression Index (BDI) and Patient Health Questionnaire 9 (PHQ-9) were used to evaluate self-reported depressive symptoms. [ncbi.nlm.nih.gov]

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Renal Function Impairment

[…] decreased mental alertness decreased urine output edema - swollen feet, hands, and ankles (face if edema is severe) fatigue (tiredness) hypertension (high blood pressure) insomnia [medicalnewstoday.com]

Early detection can help prevent the progression of kidney disease to kidney failure. Heart disease is the major cause of death for all people with CKD. [kidney.org]

We observed opioid-related respiratory depression in a patient receiving tramadol via patient-controlled analgesia. [ncbi.nlm.nih.gov]

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Young Syndrome

Almost two-thirds of women experience insomnia at least a few nights a week, according to a National Sleep Foundation poll. [elle.com]

The majority of people who die from heart failure in Ireland are aged between 60 and 80. Coronary disease causes most of these deaths over the age of 40. [irishtimes.com]

Common symptoms in depressive disorder include depressed mood, decreased interest, psychomotor slowing, sleep disturbance, and weight change. [frontiersin.org]

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Alcoholic Cardiomyopathy

Medical detox will often use medications to manage some of the more difficult withdrawal symptoms like nausea and vomiting, headaches, insomnia, fatigue, and general malaise [sdtreatmentcenter.com]

It is a major cause of dilated cardiomyopathy, and is characterised by severe left ventricular dysfunction, which may present as ventricular fibrillation or sudden death. [medical-dictionary.thefreedictionary.com]

Abstract The myocardial depressant effects of excessive ethanol consumption have long been known. [ncbi.nlm.nih.gov]

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Hypertensive Crisis

Parenteral Drugs for Hypertensive Emergencies Drug Dose Selected Adverse Effects* Special Indications Clevidipine 1–21 mg/hour IV Atrial fibrillation, fever, insomnia, nausea [msdmanuals.com]

[…] cardiovascular events, and death from cardiovascular causes; however, these drugs do not significantly reduce the risk of coronary heart disease, heart failure, or death [intranet.tdmu.edu.ua]

Tranylcypromine is a non-selective irreversible MAOI used in refractory depression and bipolar disorder. [ncbi.nlm.nih.gov]

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Autonomic Neuropathy

Insomnia Insomnia can be the consequence of either sympathetic weakness while upright during the day or parasympathetic excess state during the night. [drbuckeye.com]

A study of 120 patients with DM and no previous CAD found that CAN was a better predictor of major cardiovascular events (such as sudden death, death caused by MI, congestive [hindawi.com]

Ultimately, this constellation of features of neuropathy conspire to impede activities of daily living, especially in the patient with pain, anxiety, depression, and sleep [ncbi.nlm.nih.gov]

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Atrial Arrhythmia

[…] treatment of obesity, smoking cessation, nephropathy, pulmonary embolism, atherothrombosis, asthma, hypertension, thrombosis, arrhythmia, angina, hypertension, heart failure, insomnia [glosbe.com]

heart failure, sudden death, and cardiovascular morbidity in the world. [escardio.org]

The authors report the case of a patient with uncontrolled atrial arrhythmia who cardioverted to normal sinus rhythm after treatment of major depressive disorder (MDD) and [ncbi.nlm.nih.gov]

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Diabetic Autonomic Neuropathy

It also helps them with the depression and insomnia they may be experiencing as a result of the neuropathy." [joslin.org]

A study of 120 patients with DM and no previous CAD found that CAN was a better predictor of major cardiovascular events (such as sudden death, death caused by MI, congestive [hindawi.com]

RESULTS: The subjects were similar with the exception of depressed autonomic function in DAN subjects. [ncbi.nlm.nih.gov]

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Chronic Right-Sided Congestive Heart Failure

[…] chest pain; loss of appetite or a feeling of indigestion; clammy skin; a fast or irregular heartbeat; feelings of restlessness or confusion; difficulty remembering things; insomnia [dartmouth-hitchcock.org]

History of Congestive Heart Failure Congestive heart failure is, in a nutshell, the end stage for all chronic disease affecting the heart, and as such is a major cause of [ceufast.com]

disorder Presentation Symptoms dyspnea on exertion orthopnea paroxysmal nocturnal dyspnea fatigue pulmonary edema Physical exam cardiovascular exam pitting lower extremity [medbullets.com]

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Chronic Kidney Disease

An investigation of the causes of death associated with CKD in Alberta revealed that the major cause of death was cardiovascular (including an increase in heart failure and [link.springer.com]

Systemic inflammation, oxidative stress, elevated serum adipokines and fetuin-A, metabolic acidosis, vitamin D deficiency, depressed serum erythropoietin, endoplasmic reticulum [ncbi.nlm.nih.gov]

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