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810 Possible Causes for Depression, Muscle Weakness, Round Face

  • Cushing Syndrome

    The clinical sign indicative for CS leading to referral to the endocrinologist was muscle weakness in the man and plethora in the woman.[ncbi.nlm.nih.gov] Abstract The rationale for treating psychotic major depression with glucocorticoid receptor (GR) antagonists is reviewed.[doi.org] Symptoms include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure and high blood sugar, purple or pink stretch marks on the skin,[icd10data.com]

  • Cushing's Disease

    Some symptoms are Upper body obesity Thin arms and legs Severe fatigue and muscle weakness High blood pressure High blood sugar Easy bruising Lab tests can show if you have[fpnotebook.com] A case of Cushing disease, who presented with suicidal depression as the main complaint is reported.[ncbi.nlm.nih.gov] A 39-year-old woman with a 3-year history of a rounded face developed widespread myalgia.[ncbi.nlm.nih.gov]

  • Adrenal Cushing Syndrome

    An overproduction of the aldosterone hormone can lead to high blood pressure and to those symptoms associated with low levels of potassium, such as weakness, muscle aches,[hopkinsmedicine.org] Excess cortisol causes a host of physical and psychological problems that can range from fat redistribution and muscle problems to sexual dysfunction and depression.[endocrineny.com] People with Cushing syndrome usually develop excessive fat throughout the torso and have a large, round face and thin skin.[merckmanuals.com]

  • Polymyalgia Rheumatica

    There is no true muscle weakness nor evidence of muscle disease on electromyography (EMG) or on biopsy.[healthcentral.com] Depressive symptoms were assessed using the Patient Health Questionnaire-8 (PHQ-8), with a score of 10 defined as current depressive symptoms.[ncbi.nlm.nih.gov] Over a long period of time, corticosteroids can cause such side effects as weight gain, osteoporosis, increased risk of infection, cataracts , glaucoma, rounding of the face[healthcentral.com]

  • Addison's Disease

    The physical examination was completely normal except for muscle weakness, hyperpigmentation on labial mucosa and skin in a patient.[ncbi.nlm.nih.gov] The depression was treated safely with electroconvulsive therapy (ECT) combined with steroid cover.[ncbi.nlm.nih.gov] People with Cushing’s typically have a rounded “moon” face, gain weight around the trunk, and have slender arms and legs.[lifeextension.com]

  • Rheumatoid Arthritis

    Fatigue, muscle weakness, and weight loss are common symptoms.[britannica.com] […] with decreased depression.[ncbi.nlm.nih.gov] These side effects are serious and can include easy bruising, thinning of the bones (osteoporosis), cataracts, weight gain, a round face, susceptibility to infections, diabetes[orthop.washington.edu]

  • Vitamin D Deficiency

    Apart from the well-known effects on bone metabolism, this condition is also associated with muscle weakness, predominantly of the proximal muscle groups.[ncbi.nlm.nih.gov] BACKGROUND: Depression is a significant health and economic burden worldwide affecting not only adults but also children and adolescents.[ncbi.nlm.nih.gov] NIWA provides a year round daily guide of the UV throughout New Zealand.[health.govt.nz]

  • Hypokalemia

    Neurological examination showed a lower extremity muscle weakness with three-fifths muscular strength of the quadriceps and tibialis anterior muscle on both sides.[ncbi.nlm.nih.gov] 2 12-015 The earliest electrocardiogram (ECG) change associated with hypokalemia is a decrease in the T-wave amplitude. 1 As potassium levels decline further, ST-segment depression[doi.org] Renina: hiperaldosteronism I ii scazuta, II crescuta HTA A 34-year-old Caucasian female presents with truncal obesity, a rounded "moon face", and a "buffalo hump".[quizlet.com]

  • Congenital Muscular Dystrophy

    KEYWORDS: Collagen; Fibrosis; IGF-1; Mesenchymal; Mouse; Muscular dystrophy; Skeletal muscles; Weakness[ncbi.nlm.nih.gov] The goal of our anesthetic management was to reduce the risk of respiratory depression.[ncbi.nlm.nih.gov] DPM1 activity in fibroblasts was reduced by 80%, while affinity for the substrate was not depressed, suggesting a decrease in the amount of active enzyme.[ncbi.nlm.nih.gov]

  • Mucopolysaccharidosis

    Compression of the cervical spinal cord, caused by glycosaminoglycan infiltration of the dura, may lead to spastic paresis if not corrected by neurosurgical intervention.[orpha.net] The most common bony changes were hypo/dysplastic odontoid; cervical platyspondyly with anterior inferior beaking; thoracic posterior end plate depressions and lumbar posterior[ncbi.nlm.nih.gov] Figure 1: shows Coarse facial features with depressed nasal bridge, a short neck, long philtrum.[omicsonline.org]

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