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40 Possible Causes for Descending Paralysis, Flaccid Paralysis, Myasthenia Gravis

  • Botulism

    Abstract Botulism is the acute, flaccid paralysis caused by a neurotoxin produced by Clostridium botulinum.[ncbi.nlm.nih.gov] INTRODUCTION: Clostridium botulinum is known to cause descending paralysis in infants throughout the world.[ncbi.nlm.nih.gov] Findings that distinguish botulism from myasthenia gravis: nausea/vomiting, poorly reactive pupils, and paralysis of accommodation. [Purvin V, Kawasaki A.[web.archive.org]

  • Tick Paralysis

    Abstract Tick paralysis is a rare disease characterized by acute, ascending, flaccid paralysis that is often confused with other acute neurologic disorders or diseases (e.g[ncbi.nlm.nih.gov] […] that the acute ascending or rare descending type of paralysis originally described by Landry is simply a form of poliomyelitis, whereas others contend that Landry's paralysis[annals.org] gravis.[ncbi.nlm.nih.gov]

  • Guillain-Barré Syndrome

    CASE REPORT: An 82-year-old woman presented with acute ascending flaccid paralysis and acute respiratory failure.[ncbi.nlm.nih.gov] For example, in 1986, Ropper described patients who developed rapidly progressive oropharyngeal, neck and shoulder weakness that mimicked the descending paralysis seen in[vdocuments.net] Many neurologists are unfamiliar with PCB, which is often misdiagnosed as brainstem stroke, myasthenia gravis or botulism.[ncbi.nlm.nih.gov]

  • Wound Botulism

    The clinical picture of botulism is of descending, symmetric, flaccid paralysis.[ncbi.nlm.nih.gov] Wound botulism in 7 heroin 'skin poppers' produced ophthalmoplegia and descending paralysis.[ncbi.nlm.nih.gov] Wound botulism may be underdiagnosed because of confusion with inflammatory neuropathy or myasthenia gravis.[ncbi.nlm.nih.gov]

  • Infantile Botulism

    paralysis.[pediatricneurologybriefs.com] Note that, in many cases, descending paralysis may be absent.[symptoma.com] gravis and other myoneural disorders 2016 2017 2018 2019 Non-Billable/Non-Specific Code Diagnosis Index entries containing back-references to A48.51 : Botulism (foodborne[icd10data.com]

  • Deliberate Exposure to Botulinum Toxin

    Situations suggesting release of botulinum toxin as a biological weapon: (1) Outbreak of acute flaccid paralysis with prominent bulbar palsies (diplopia, dysarthria, dysphonia[meducator3.net] Conclusions: An aerosolized or foodborne botulinum toxin weapon would cause acute symmetric, descending flaccid paralysis with prominent bulbar palsies such as diplopia, dysarthria[experts.umn.edu] Differential diagnoses include Guillian-Barre syndrome and its Miller Fisher variant, organophosphate poisoning, and myasthenia gravis.[icmcasesummaries.com]

  • Intestinal Botulism

    Botulism manifests as acute, descending, symmetric flaccid paralysis caused by neurotoxin-mediated blockade of presynaptic acetylcholine release [ 1 ].[academic.oup.com] Intestinal colonization botulism, rare in adults, should be considered for patients with descending paralysis, especially those with a preceding alteration in small bowel[ncbi.nlm.nih.gov] Tensilon test: A normal test helps to differentiate botulism from myasthenia gravis; borderline positive tests can occur in botulism.[cdc.gov]

  • Inhalational Botulism

    It is characterized by symmetric cranial nerve palsy, commonly followed by symmetric, descending, flaccid paralysis of involuntary muscles, which may result in respiratory[pedsinreview.aappublications.org] Recognition of the clinical presentation characterized by bulbar palsies and descending paralysis in the absence of sensory or central nervous systems symptoms is key to making[ohsu.pure.elsevier.com] We initially considered conditions such as Myasthenia Gravis or Guillain-Barre. However, the eye symptoms are not typical of these conditions.[vephealthcare.com]

  • Neuromuscular Junction Disorder

    Differential diagnosis of flaccid paralysis Anterior horn disease Disorders of the NMJ  Polyemyelitis  Amyotrophic lateral sclerosis  Myasthenia gravis  Lambert-Eaton[slideshare.net] In its nontherapeutic form, the toxin is produced by bacteria and can cause a paralysis that starts with the muscles of the face and throat and descends over the rest of the[verywell.com] Transient neonatal myasthenia gravis is self-limited with a reported duration of 5 to 47 days with a mean duration of 18 days (133).[academlib.com]

  • Respiratory Muscle Paralysis

    The clinical presentation appears as typical ascending flaccid paralysis.[cvbd.org] Foodborne botulism is characterized by descending, flaccid paralysis that can cause respiratory failure.[who.int] Abstract A 34-year-old lady presented with generalised weakness of body, indistinguishable from myasthenia gravis within 24 hours of a wasp sting.[ncbi.nlm.nih.gov]

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