Desquamating Rash: Causes & Reasons

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Possible Causes for Desquamating Rash

Toxic Shock Syndrome

Staphylococcal TSS is defined by fever; diffuse macular rash; desquamation of the rash 1 to 2 weeks after the onset of illness with involvement of the palms and soles; hypotension [errolozdalga.com]

Staphylococcal toxic shock syndrome (TSS) has rarely been reported without rash and desquamation. [ncbi.nlm.nih.gov]

BACKGROUND: Toxic shock syndrome (TSS), which can be life-threatening, is clinically and pathologically characterized by the presence of high fever, skin rash, desquamation [ncbi.nlm.nih.gov]

Scarlet Fever

[…] and soles may occur Desquamation Follows rash fading after several weeks Desquamation of face, skin folds, hands and feet Desquamation may last up to 6 weeks VI. [fpnotebook.com]

[…] phase Appears 7–10 days after resolution of rash Skin desquamation: desquamation of the skin in flakes Affects face, trunk, hands, fingers, and toes Findings atypical of [amboss.com]

Chronic Arsenic Poisoning

Over the next 2 weeks he developed profound distal weakness, desquamating rash over trunk and limbs, rain drop pigmentation ( Figure 1A ) and Mees’ lines ( Figure 1B ). 24 [academic.oup.com]

Toxic Epidermal Necrolysis

[…] with desquamation over one to two weeks; erythema and edema of palms and soles; high fever; hyperemia of conjunctiva and mucous membranes; hypotension; involvement of 3 or [aafp.org]

[…] on palms and soles that evolves to desquamation over about 2 wk) Paraneoplastic pemphigus (sometimes with different mucocutaneous findings or in patients with evidence of [merckmanuals.com]

[…] on palms and soles that evolves to desquamation over about 2 weeks) Paraneoplastic pemphigus (sometimes with different mucocutaneous findings or in patients with evidence [merckmanuals.com]

Arsenical

He had a several week history of vomiting, weight loss, a widespread desquamating skin rash, and symptoms and signs of a progressive painful sensorimotor neuropathy. [pn.bmj.com]

Boric Acid

[…] skin rashes and to allow the initiation of appropriate clinical care. [ncbi.nlm.nih.gov]

[…] published material on the symptoms and histopathology following boric acid ingestion, but knowledge of this entity is important, both to differentiate it from other causes of desquamative [ncbi.nlm.nih.gov]

Atopy

[…] at·o·py | \ ˈa-tə-pē \ : a genetic disposition to develop an allergic reaction (such as allergic rhinitis or asthma ) and produce elevated levels of IgE upon exposure to an environmental antigen and especially one inhaled or ingested Other Words from atopy atopic \ (ˌ)ā-ˈtä-pik, -ˈtō- \ adjective First Known Use[…] [merriam-webster.com]

Pneumococcal Pneumonia

We describe a case of bacteremic, leukopenic pneumococcal pneumonia with respiratory failure, accompanied by diabetic ketoacidosis and hypothermia. Pulmonary leukostasis may play a role in the pathogenesis of the acute respiratory distress syndrome (ARDS) in pneumococcal pneumonia. The patient recovered with[…] [ncbi.nlm.nih.gov]

Exfoliative Dermatitis

Human immunodeficiency virus-infected patients are at increased risk of drug reactions because of immune dysregulation and multiple drug intake. Lichenoid drug reactions to isoniazid have been reported previously in the literature. However, for lichenoid drug reaction to isoniazid to be so extensive to present as[…] [ncbi.nlm.nih.gov]

Dermatomyositis

Dermatomyositis Discrete red areas overlying the knuckles in a person with juvenile dermatomyositis. These are known as Gottron's papules. Specialty Rheumatology Symptoms Rash, muscle weakness, weight loss, fever[1] Complications Calcinosis, lung inflammation, heart disease[1][2] Usual onset 40s to 50s[3] Duration[…] [en.wikipedia.org]

Arsenic-Induced Polyneuropathy

Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. [xmri.com]

Acute Arsenic Poisoning

Arsenic is highly toxic and can enter the body through the gastrointestinal tract, skin or lungs. Acute arsenic poisoning can occur through ingestion of contaminated water, occupational exposure and deliberate poisoning. Acute arsenic poisoning (AAP) can present with a number of features. Exposure to non-lethal[…] [symptoma.com]

Streptococcus Pyogenes Pneumonia

Symptoms mimicking scarlet fever, including desquamating rash, may be observed in rare cases [ 7 ]. [ncbi.nlm.nih.gov]

Severe community acquired pneumonia associated with a desquamating rash due to group A beta-haemolytic streptococcus. [ncbi.nlm.nih.gov]

[…] skin rash - Alive Brusch et al [ 13 ] 1996 51, male - 1 week 105/55 mm Hg, 130 bpm, 38.5 °C VCM + EM + DOXY Supraventricular tachycardia, multiple organ failure - Dead on [ncbi.nlm.nih.gov]

Streptococcal Toxic Shock Syndrome

The toxic shock syndrome is a sporadic, febrile illness that is characterized by fever, hypotension, and a desquamating rash. [histopathology-india.net]

Skin rash and desquamation were found subsequently during the recovery phase. The blood and sputum cultures were sterile. [ncbi.nlm.nih.gov]

Atypical Measles

[…] for1-2days Streptococcus Angina, strawberry tongue an erythematous base higher as the Circumoral pallor, tonsillitis for 3-5 day, desquam- rash appears ation after 1 week [slideshare.net]

Morbilliform rash. Patients appear most ill during the first or second day of the rash. [emedicine.medscape.com]

Communicability begins several days before and continues until several days after the rash appears. Measles is not communicable once the rash begins to desquamate. [merckmanuals.com]

Kwashiorkor

Finally, we present a differential diagnosis for any child with a generalized eczematous or desquamative rash. [ncbi.nlm.nih.gov]

New-onset edema and desquamative rash in a child, especially a child with cerebral palsy, should alert physicians to the possibility of acute kwashiorkor and prompt investigation [mdedge.com]

rash, hair discolouration, and a large fatty liver. [en.wikipedia.org]

Arsenic Trioxide

Arsenic trioxide has become the treatment of choice for patients with acute promyelocytic leukaemia. Cardiovascular toxicity is known to occur with this therapy, in particular heart rhythm disorders due to QT interval prolongation. We present a case of ventricular arrhythmia with no QT prolongation in a patient[…] [ncbi.nlm.nih.gov]

Late Congenital Syphilis

[…] skin rash, low birth weight, pneumonia, and severe anemia. [aao.org]

The fetal stigmata seen before the age of 2 years include eruptions characteristic of secondary syphilis, such as maculopapular rash and desquamating erythema of the palms [dartmouth.edu]

(with desquamation of the palms and soles ) Skeletal abnormalities (e.g., osteodystrophy ) Late congenital syphilis (onset > 2 years ) Facial abnormalities: rhagades, saddle [amboss.com]

Vulvar Disorder

In Kawasaki disease, an erythematous, desquamating perineal rash may occur in the second week of symptom onset, almost at the same time as palmoplantar desquamation. [en.wikipedia.org]

In Kawasaki’s disease ( fig. 10- Perineal desquamation in Kawasaki disease ), an erythematous, desquamating perineal rash may occur in the second week of symptom onset, almost [health.am]

[…] at the same time as palmoplantar desquamation. [health.am]

Kawasaki Disease

Typical findings in both adults and children include fever, conjunctivitis, pharyngitis, and skin erythema progressing to a desquamating rash on the palms and soles. [ncbi.nlm.nih.gov]

An erythematous desquamating perineal rash is a valuable early clinical clue, which might facilitate a prompt diagnosis of KD. [ncbi.nlm.nih.gov]

Acrodynia

He was irritable and depressed, and had a diffuse itching papular rash with palmar erythema and superficial desquamation (fig 1). [doi.org]

Figure 1 Diffuse itching papular rash with palmar erythema and superficial desquamation in a 4½ year old boy. References ↵ Ellenhorn MJ, Schonwald S, Ordog G, et al. [doi.org]

[…] and superficial desquamation. [doi.org]

Bullous Impetigo

A desquamating rash; staphylococcal skin syndrome. Ann Emerg Med. 2013;61:118, 129. http://www.ncbi.nlm.nih.gov/pubmed/23260687 Kress DW. [rarediseases.org]

It causes fever, diffuse erythematous then desquamating rash, hypotension and involvement of other organs. [dermnetnz.org]

Meropenem Allergy

[…] with desquamation 3–4 days after initiation ■ Recovered in approximately 25 days ● Not challenged with another carbapenem Case 1: Positive delayed reading ID skin test to [ncbi.nlm.nih.gov]

[…] micropapular exanthema ● Challenged with meropenem 6 years later ■ Tolerated course with no reaction Case 2: ● Treated with meropenem ■ Developed generalized scaly erythematous rash [ncbi.nlm.nih.gov]

Pulmonary Arteritis

Patients may present with fever, conjunctivitis, lymphadenopathy, erythematous desquamating rash, oral mucositis and arthritis. [aafp.org]

Kawasaki disease, on the other hand, is a disease which usually occurs in children and is associated with a desquamating rash which is often accompanied by mucosal ulceration [thorax.bmj.com]

Kawasaki disease Fever, conjunctivitis, lymphadenopathy, desquamating rash, mucositis, arthritis, coronary artery aneurysms High-dose aspirin and intravenous immune globulin [aafp.org]

Congenital Syphilis

[…] skin rash, low birth weight, pneumonia, and severe anemia. [aao.org]

Case 2, an Aboriginal baby of six weeks, came with more classic symptoms and signs--rhinorrhea, rash with desquamation, irritability, anaemia, and lack of movement in an upper [ncbi.nlm.nih.gov]

[…] early congenital syphilis (age 2 years or younger) include hepatosplenomegaly, characteristic changes of the long bones on radiographic examination, abdominal distention, desquamative [aao.org]

Otitis Media

S pyogenes may be associated with streptococcal toxic shock syndrome, which may include coagulopathy, soft tissue necrosis or fasciitis, desquamating rash, and liver or renal [web.archive.org]

Rubella-Associated Arthritis

[…] spreads to trunk and extremities may be itchy desquamates rash resolves in 3 days petechial rash on soft palate (Forschheimer spots) orchitis Studies Labs detection of rubella-specific [medbullets.com]

[…] postauricular lymphadenopathy is classic may also have posterior cervical and suboccipital lymphadenopathy fine, pink, non-confluent maculopapular rash starts on face and [medbullets.com]

[…] low-grade fever polyarthritis and polyarthralgia more common in adult females fingers, wrists, and knees are most commonly involved Physical exam lymphadenopathy before the rash [medbullets.com]

Neonatal Inflammatory Skin and Bowel Disease Type 2

Scarlet fever – Exotoxin-mediated diffuse erythematous rash – Pharyngitis due to group A streptococcus – Coarse, sandpaper-like, erythematous, blanching rash à desquamation [learn.pediatrics.ubc.ca]

– Rash – Cervical lymphadenopath – Acute rheumatic fever 3. [learn.pediatrics.ubc.ca]

[…] conjunctival injection, injected or fissured lips – Injected pharynx or “strawberry tongue” – Erythema of palms or soles – Edema of hands or feet – Generalized or periungual desquamation [learn.pediatrics.ubc.ca]

Arsenic Poisoning

Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (mees) lines in the fingernails. [icd9data.com]

Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. [ncbi.nlm.nih.gov]

Staphylococcal Scalded Skin Syndrome

A desquamating rash; staphylococcal skin syndrome. Ann Emerg Med. 2013;61:118, 129. http://www.ncbi.nlm.nih.gov/pubmed/23260687 Kress DW. [rarediseases.org]

A scarlatiniform rash was observed on the body, and this erythema was followed by generalized desquamation. [ncbi.nlm.nih.gov]

The rash fades within a week and is followed a week later by a superficial desquamation, especially in skin folds, on the face and in sheets from the hands and feet (may take [healio.com]