Development Normal: Causes & Reasons

Possible Causes for Development Normal

Less than 10 patients have been reported, and the phenotype can range from severe neurologic involvement with mental retardation and seizures to normal neurologic development [diseaseinfosearch.org]

See Developmental milestone, Developmental red flag. de·vel·op·men·tal de·lay ( dĕ-vel'ŏp-men'tăl dĕ-lā' ) Lack of normal intellectual growth and development. [medical-dictionary.thefreedictionary.com]

Her development was normal until the age of 5 months when she developed fever and convulsion. [karger.com]

Neonatal Adrenoleukodystrophy

Clinical symptoms typically begin in the first few years of life, following a normal to mildly delayed early development. [rarediseases.org]

The discriminant function reported in Moser et al [] fully separates normal control males from affected males. [mclaughlinanderson.mobi]

Takeda K, Nomura Y, Sakuma H et al. (1997) MR assessment of normal brain development in neonates and infants: comparative study of T1- and diffusion-weighted images. [mrineonatalbrain.com]

Mayer-Rokitansky-Küster-Hauser Syndrome

(normal breast and pubic as well as axillary hair development in the presence of primary amenorrhoea). [casereports.bmj.com]

It is characterized by the failure of the uterus and the vagina to develop properly in women who have normal ovarian function and normal external genitalia. [miklosandmoore.com]

They are usually sporadic, although familial cases have also been described, denoting a probable genetic cause.1 Affected women have normal growth and pubertal development [casereports.bmj.com]

Rett Syndrome

Pregnancy and delivery were uneventful, child developed normally till age 12 years when her development began to decline. [ncbi.nlm.nih.gov]

Infants appear to develop normally for the first several months before development stalls (typically between the ages of 6-18 months). [ninds.nih.gov]

Babies with Rett syndrome seem to grow and develop normally at first. Between 3 months and 3 years of age, though, they stop developing and even lose some skills. [medlineplus.gov]

Agenesis of Uterus

An MRKH patient is a genetic female with normal female chromosomes (46XX) and normal ovaries and, therefore, develops normal external female characteristics, including breasts [miklosandmoore.com]

Women with MRKH have normal ovaries and will have normal development of breasts, clitoris, (part of the vulva) and vulva (external genetalia). [gondracenter.com]

All women with MRKH have functional ovaries, develop normally, and produce the normal level of hormones. [arm.coloradowomenshealth.com]

Pes Planus

Most children are flat-footed until they are between the ages of 3 and 5 when their longitudinal arch develops normally. [special-tests.com]

Most children are flat-footed until they are about ages 3 to 5 when their longitudinal arch develops normally. What are the symptoms? [myhealth.alberta.ca]

For children, treatment using corrective shoes or inserts is rarely needed, as the arch usually develops normally by age 5.Surgery is rarely needed. [special-tests.com]

Delayed Male Puberty

This wide range in age is normal, and it's why you may develop several years earlier (or later) than most of your friends. [kidshealth.org]

If delayed puberty is due to a disease, such as underactive thyroid gland, treating it may help puberty to develop normally. [medlineplus.gov]

Symptoms of delayed puberty are basically that development is not occurring as it normally should. Delayed sexual development to a reproducing adult is the result. [newportchildren.com]

Isolated Partial Vaginal Agenesis

Normally, one of these ducts develops into the uterus and vagina, and the other grows into fallopian tubes. [mayoclinic.org]

development of secondary sexual characteristics and normal external genitalia. [orpha.net]

It is characterized by the failure of the uterus and the vagina to develop properly in women who have normal ovarian function and normal external genitalia. [rarediseases.org]

Benign Familial Infantile Epilepsy Type 4

BFIE is a disorder that occurs in previously healthy infants who are developing normally. [news-medical.net]

BFIE is a disorder which place turkey in previously healthy infants who’re developing normally. [frankhimpslarchive.com]

Inclusion criteria for BIS were as follows: 1) age of onset 2-24 months; 2) normal development; 3) normal interictal EEG; 4) normal brain imaging; and 5) good response to [pediatricneurologybriefs.com]

Trisomy X Syndrome

The other cells in the developing fetus are very much normal and have a pair of X chromosomes each. [ayushveda.com]

[…] are usually normally developed, although babies may be floppy (hypotonic) and weight may be slightly lower than average. [contact.org.uk]

Beginning around the normal age of puberty, estrogen replacement therapy can result in some breast development and menstruation. [www2.palomar.edu]

Congenital Hip Dysplasia

This secures both of your baby's hips in a stable position and allows them to develop normally. Credit: DR P. [nhs.uk]

Developmental dysplasia of the hip (DDH), also known as hip dysplasia, is a congenital condition in which the hip joint doesn’t develop normally. [childrenshospital.org]

Without treatment, DDH may lead to problems later in life, including: developing a limp hip pain – especially during the teenage years painful and stiff joints ( osteoarthritis [nhs.uk]

Frasier Syndrome

The WT1 gene, which is essential for normal kidney and gonadal development, encodes a zinc finger transcription factor. [ncbi.nlm.nih.gov]

Molecular pathology Defects of WTI, which encodes a transcription factor that plays an essential role in the normal development of the urogenital system, cause Frasier syndrome [medical-dictionary.thefreedictionary.com]

It is proposed that the clinical definition of Frasier syndrome should be broadened to include 46,XX females with normal genital development and focal segmental glomerulosclerosis [ncbi.nlm.nih.gov]

Leydig Cell Hypoplasia due to LHB Deficiency

Leydig cell hypoplasia is an autosomal recessive disorder in which loss of function of the LHCGR gene in the male prevents normal sexual development. [ncbi.nlm.nih.gov]

[…] sexual development. [diseaseinfosearch.org]

Genetic females with these mutations have normal female external genitalia and normal female development during puberty, but may have amenorrhea (absent periods) and infertility [rarediseases.info.nih.gov]

Leydig Cell Hypoplasia

Leydig cell hypoplasia is an autosomal recessive disorder in which loss of function of the LHCGR gene in the male prevents normal sexual development. [ncbi.nlm.nih.gov]

[…] sexual development. [diseaseinfosearch.org]

Female Infertility due to Anovulation

On physical exam, there is normal breast development; however, her uterus is not palpable. This is confirmed by pelvic ultrasound. [medbullets.com]

Artificial means are the only way to develop a normal female body into adulthood. [allthingsvagina.com]

Gonadal dysgenesis causes infertility & inhibits normal sexual development. [signssymptoms.org]

46,XX Ovotesticular Disorder of Sex Development

A normal scrotum will develop. The underdeveloped gonad on the other side may not make testosterone or MIS. [cincinnatichildrens.org]

Artificial means are the only way to develop a normal female body into adulthood. [allthingsvagina.com]

The first known step of sexual differentiation of a normal XY fetus is the development of testes. [wwwowww.me]

Mosaic Monosomy X

Women with Turner syndrome are shorter than average and cannot have children because their ovaries do not develop normally. [encyclopedia.com]

Beginning around the normal age of puberty, estrogen replacement therapy can result in some breast development and menstruation. [www2.palomar.edu]

One or more cells may fail to survive thawing, yet the embryos from such develop into normal offspring. [sbivf.com]

Lissencephaly

Some will survive, but show no significant development -- usually not beyond a 3- to 5-month-old level. Others may have near-normal development and intelligence. [ninds.nih.gov]

Other people, however, may develop normally and show few signs of a learning disability. [webmd.com]

The NINDS conducts and supports a wide range of studies that explore the complex systems of normal brain development, including neuronal migration. [ninds.nih.gov]

Myoclonic-Astatic Epilepsy

Before the onset of SMEI, MAE, and ABPE/PLS, the development of the child is usually normal. [ncbi.nlm.nih.gov]

Statistics show that it usually affects children who have previously developed normally, and boys are twice as likely as girls to develop MAE. [epilepsywarriors.org]

Neurological examination and head size are normal. Development and cognition is typically normal, however impairments may develop at or after seizure onset. [epilepsydiagnosis.org]

Transient Neonatal Hypothyroidism

Bone age, 99mTc scans and ultrasonographic findings were all normal, and evaluation of physical development was normal too, as were the serum levels of TT3, TT4 and TSH after [ncbi.nlm.nih.gov]

This gland is responsible for secreting a hormone called thyroxine (T4) which plays a vital role in normal growth and development in children. [magicfoundation.org]

Agenesis or Aplasia of Uterine Body

Patients with MRKH have normal breast development, normal secondary sexual body proportions, body hair, and hymenal tissue. [academiawomenshealth.com]

Her exam reveals normal female external genitalia and normal breast and pubic hair development. [medbullets.com]

They also have normal female external genitalia and normal breast and pubic hair development, thus showing normal development of secondary sexual characteristics. [ijogr.com]

Trisomy 20

A healthy male infant was delivered at term, with no dysmorphology or apparent malformations; this baby is developing normally. [ncbi.nlm.nih.gov]

All of them revealed normal karyotypes. The baby is developing normally at the age of 2 years. [ncbi.nlm.nih.gov]

The phenotypically normal male baby is developing normal. [ncbi.nlm.nih.gov]

Reifenstein Syndrome

Complications Breast development in men Infertility and failure to develop normal male genitals Psychological problems, such as depression Calling your health care provider [coordinatedhealth.com]

Complications Infertility and failure to develop normal male gonads/genitals. Breast development in men can be a cosmetic concern. [medical-dictionary-search-engines.com]

People with Reifenstein syndrome can have a normal lifespan and be totally healthy, but they may be have difficulty making a baby. [coordinatedhealth.com]

Aicardi's Syndrome

Other parts of the brain also do not develop normally. These brain malformations cause frequent seizures and intellectual disability. [rarediseases.org]

Babies with Aicardi-Goutieres Syndrome develop normally for several months but then begin to develop encephalopathy (brain disease). [sema4.com]

normally. [disorders.eyes.arizona.edu]

Uterine Cervical Aplasia and Agenesis

They also have normal female external genitalia and normal breast and pubic hair development, thus showing normal development of secondary sexual characteristics. [ijogr.com]

Their ovaries are normal, and the secondary sexual characteristics develop normally. [jhrsonline.org]

C, Axial CT scan of the skull base shows absence of the left carotid canal and a normally developed right carotid canal ( arrow ). [ajnr.org]

Bleeding from an Ectopic Pregnancy

Some research suggests that human fetuses exposed only to mifepristone continue to develop normally. 33 [consult.womenhelp.org]

The fertilized egg cannot develop normally and receive nutrition in these locations. [babyhopes.com]

Even if the embryo develops normally, the pregnancy can still end in tragedy. On the next page you'll learn about the factors that lead to a stillbirth. [health.howstuffworks.com]

Amblyopia

then the brain interferes with the development of normal vision. [coopereyecare.com]

normally. [visionaware.org]

Understanding the Critical Period The visual pathways continue to develop in early childhood, during “critical periods” of development. [visionaware.org]

Folate-Deficiency Anemia

This is when the brain or spinal cord doesn’t develop normally. [elcaminohospital.org]

Sometimes these red blood cells don’t live as long as normal red blood cells. What causes folate-deficiency anemia? [urmc.rochester.edu]

This is when the brain or spinal cord doesn’t develop normally. It can cause death before or soon after birth. Or it may cause paralysis of the legs. [elcaminohospital.org]

Acquired Epileptic Aphasia

Children may be developing normally when the seizures first start. Yet usually 1 to 2 years later, a progressive decline in cognitive functioning happens. [epilepsy.com]

The condition should be suspected if a child with normal development shows a fairly abrupt loss of established language skills. [tidsskriftet.no]

Characteristics of Landau Kleffner Syndrome Sudden or gradual development of aphasia (receptive and expressive) after initially normal speech development. [docneuro.com]

NEMO Mutation with Immunodeficiency

An embryo develops, but many organ systems fail to develop normally, including the immune system. [primaryimmune.org]

Lymphocyte subsets are often normal and common clinical tests of T-cell function are normal or only subtly diminished. [primaryimmune.org]

This lack of response is notable even in patients with normal total serum immunoglobulin levels. [primaryimmune.org]