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714 Possible Causes for Diarrhea, Easy Bruising, Hepatosplenomegaly

  • Chronic Alcoholism

    OBJECTIVE: Diarrhea, weight loss and osteoporosis are prominent symptoms and clinical signs of alcoholism.[ncbi.nlm.nih.gov] bruising Cardiovascular system —causing abnormal heart beat/heart rate, heart failure, high blood pressure (hypertension), and other conditions Gastrointestinal (GI) tract[healthcommunities.com] Symptoms of the disease include anorexia, diarrhea, weight loss, neurologic and psychiatric disturbances (most notably depression), and fatty deterioration of the liver, sometimes[omicsonline.org]

  • Acute Myelocytic Leukemia

    In all three patients, radionuclide imaging with technetium-99m sulfur colloid showed hepatosplenomegaly, decreased liver uptake, and increased splenic activity.[ncbi.nlm.nih.gov] The patient presented with an acute abdomen with clinical findings of acute cholecystitis, subileus, and local pain in the right upper abdomen accompanied by severe diarrhea[ncbi.nlm.nih.gov] Symptoms of AML include: Fever Shortness of breath Easy bruising or bleeding Bleeding under the skin Weakness or feeling tired Weight loss or loss of appetite Tests that examine[nlm.nih.gov]

  • Multiple Myeloma

    The presenting problem was proteinuria in five patients, thyromegaly in three patients, and hepatosplenomegaly in one patient.[jamanetwork.com] For this reason we report this rare case in which diarrhea and abdominal pain were the initial presenting symptoms of multiple myeloma with a plasmacytoma.[ncbi.nlm.nih.gov] bruising or bleeding – due to low platelet numbers Bleeding from the nose or gums Repeated infections or infections that are hard to get rid of Thirst, nausea, vomiting or[betterhealth.vic.gov.au]

  • Amyloidosis

    Hepatosplenomegaly and adrenal insufficiency are common in the advanced stage of AA amyloidosis.[intechopen.com] Pedigree of Family with a PRNP Y163X Mutation Associated with Chronic Diarrhea and Autonomic Failure.[doi.org] bruising or bleeding Pancreas - Diabetes Musculoskeletal system - Joint pain or swelling, weakness Skin - Lumps or purple discoloration No one knows what causes amyloidosis[health.harvard.edu]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Occasionally, patients may have diarrhea related to pressure on the colon.[emedicine.medscape.com] Easy bruising or bleeding. Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com]

  • Waldenstrom Macroglobulinemia

    Most commonly it presents with cytopenia, hepatosplenomegaly, lymphadenopathy, constitutional symptoms, and hyperviscosity syndrome.[ncbi.nlm.nih.gov] Tests reported noninflammatory diarrhea, severe hypoalbuminemia of 1.6 g/dL, and prolonged coagulation times.[revistagastroenterologiamexico.org] The covered platelet cells may not work right, resulting in bleeding and easy bruising. Every year, there are five new cases of macroglobulinemia per 1,000,000 people.[uihc.org]

  • Primary Biliary Cirrhosis

    In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena.[ncbi.nlm.nih.gov] After the pneumonia improved, she developed severe watery diarrhea. Although vancomycin was administered enterally, the diarrhea persisted.[ncbi.nlm.nih.gov] Patients may have a low platelet count because of an enlarged spleen causing easy bruising.[medicinenet.com]

  • Viral Hepatitis

    Hepatosplenomegaly and laboratory evidence of mild to moderate hepatic dysfunction are the predominant features, with increased aminotransferases and alkaline phosphatase[doi.org] In older cattle bovine virus diarrhea (mucosal disease) is the major cause.[medical-dictionary.thefreedictionary.com] Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis[medlineplus.gov]

  • Hepatitis B

    It is similar to chronic liver disease because of signs and symptoms such as fever, weight loss, hepatosplenomegaly, and pancytopenia.[ncbi.nlm.nih.gov] Symptoms that can occur include mild fever, headache, fatigue, loss of appetite, nausea and vomiting, diarrhea, muscle and joint pain, abdominal pain, a skin rash, and jaundice[emoryhealthcare.org] bruising and bleeding Chronic HBV infection can lead to serious liver disease, liver scarring (cirrhosis), and hepatocellular (liver) cancer.[sfcdcp.org]

  • Familial Myelofibrosis

    The illness presented with pallor, haemorrhagic symptoms, and hepatosplenomegaly, and the blood picture was that of pancytopenia and leucoerythroblastosis.[ncbi.nlm.nih.gov] Because platelets play an essential role in homeostasis, thrombocytopenia results in easy bruising and a propensity to bleed.[symptoma.com] bruising, nosebleeds or heavy periods Gastrointestinal bleeding or blood in the urine Thrombotic complications can also occur, resulting in: Stroke Transient ischemic attack[mpnresearchfoundation.org]

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