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205 Possible Causes for Diarrhea, Easy Bruising, Macrocytosis

  • Vitamin B12 Deficiency

    The following are the signs and symptoms of vitamin B12 deficiency: Fatigue Weight loss Palpitations Development of sore in the mouth and tongue Diarrhea Problems with menstrual[symptoma.com] It may also cause easy bruising or bleeding, including bleeding gums, gastrointestinal side effects including sore tongue, stomach upset, weight loss, and diarrhea or constipation[en.wikipedia.org] We report a case of a 46-year-old Moroccan man presenting with severe hemolytic anemia, thrombocytopenia, and renal failure in absence of macrocytosis, thus mimicking a genuine[ncbi.nlm.nih.gov]

  • Chronic Alcoholism

    OBJECTIVE: Diarrhea, weight loss and osteoporosis are prominent symptoms and clinical signs of alcoholism.[ncbi.nlm.nih.gov] bruising Cardiovascular system —causing abnormal heart beat/heart rate, heart failure, high blood pressure (hypertension), and other conditions Gastrointestinal (GI) tract[healthcommunities.com] Alcohol is a common cause of macrocytosis, with a mean corpuscular volume (MCV) of 100-110 fL seen in a majority of patients.[symptoma.com]

  • Celiac Disease

    The patient's diarrhea resolved after initiation of a gluten free diet. He gained 25 kilograms after discharge and did not require further hospitalizations for diarrhea.[ncbi.nlm.nih.gov] bruising Depression or anxiety Fatigue Growth delay in children Hair loss Itchy skin with a rash ( dermatitis herpetiformis ) Missed menstrual periods Mouth ulcers Muscle[nlm.nih.gov] […] as can be seen in CD can result in atypical findings on the blood smear, and patients with deficiencies of folate and vitamin B 12 may not present with the characteristic macrocytosis[bloodjournal.org]

  • Malabsorption Syndrome

    When such diarrhea is chronic, the associated general malabsorptive state results in malnutrition.[doi.org] bruising; tingling in fingers or toes; and numbness or burning sensation in legs or feet.[encyclopedia.com] In this setting, microcytic anaemia usually implies iron deficiency and macrocytosis can be caused by impaired folic acid or B12 absorption or both.[en.wikipedia.org]

  • Multiple Myeloma

    For this reason we report this rare case in which diarrhea and abdominal pain were the initial presenting symptoms of multiple myeloma with a plasmacytoma.[ncbi.nlm.nih.gov] bruising or bleeding – due to low platelet numbers Bleeding from the nose or gums Repeated infections or infections that are hard to get rid of Thirst, nausea, vomiting or[betterhealth.vic.gov.au] An 80-year-old female with relapsed multiple myeloma presented with severe diarrhea, nausea, vomiting, abdominal pain, and acute renal failure 3 weeks after starting ixazomib[ncbi.nlm.nih.gov]

  • Tropical Sprue

    CONCLUSION: Tropical sprue presents with diarrhea, anorexia, weight loss, and megaloblastic anemia. The partial villous atrophy has been a constant finding.[ncbi.nlm.nih.gov] Neither patient was anemic, although one had hypersegmented polymorphonuclear leukocytes and both had macrocytosis and megaloblastic bone marrows.[ncbi.nlm.nih.gov] Macrocytosis occurs early. Serum and erythrocyte levels of folate are low. Anaemia may also be hypochromic from defective absorption of iron.[histopathology-india.net]

  • Whipple Disease

    Thus, it represents an important differential diagnosis of chronic diarrhea.[ncbi.nlm.nih.gov] Signs and symptoms [ edit ] The most common symptoms are diarrhea, abdominal pain, weight loss, and joint pains.[en.wikipedia.org] Common symptoms of the disease are abdominal pain, diarrhea, painful joints, weight loss and fever.[symptoma.com]

  • Alcoholic Liver Disease

    People who drink more than two alcoholic drinks per day are at risk of liver disorders, the most common symptoms of which include nausea, diarrhea, anorexia, abdominal pain[hospital.uillinois.edu] bruising accumulation of extra fluid in the legs , known as edema.[the-alcoholism-guide.org] Other laboratory findings include red blood cell macrocytosis (mean corpuscular volume 100) and elevations of serum gamma-glutamyl transferase (GGT), alkaline phosphatase[en.wikipedia.org]

  • Pancreatic Insufficiency

    In our patients with refractory diarrhea and low FE1, PERT provided immediate symptomatic relief.[ncbi.nlm.nih.gov] This can lead to nutrition-related disease such as weak bones, vision problems, easy bruising, and skin rashes.[animatedpancreaspatient.com] METHODS: The study included patients who met the Rome II criteria for D-IBS, patients with chronic diarrhea, and subjects without diarrhea (controls).[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Occasionally, patients may have diarrhea related to pressure on the colon.[emedicine.medscape.com] Easy bruising or bleeding. Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com] Hydroxycarbamide therapy can also cause macrocytosis and granulocyte hypersegmentation, which are unrelated to vitamin B12 or folic acid status [48] Gilbert HS.[doi.org]

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