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168 Possible Causes for Diarrhea, Easy Bruising, Progressive Polyneuropathy

  • Vitamin B12 Deficiency

    The following are the signs and symptoms of vitamin B12 deficiency: Fatigue Weight loss Palpitations Development of sore in the mouth and tongue Diarrhea Problems with menstrual[symptoma.com] The symptoms of B12 deficiency include tiredness, light-headedness , rapid heart rate , easy bruising and bleeding, weight loss, bowel upset and sore tongue.[healthdirect.gov.au] peripheral neuropathy, and spinal degeneration.[ncbi.nlm.nih.gov]

  • Chronic Alcoholism

    OBJECTIVE: Diarrhea, weight loss and osteoporosis are prominent symptoms and clinical signs of alcoholism.[ncbi.nlm.nih.gov] bruising Cardiovascular system —causing abnormal heart beat/heart rate, heart failure, high blood pressure (hypertension), and other conditions Gastrointestinal (GI) tract[healthcommunities.com] Symptoms of the disease include anorexia, diarrhea, weight loss, neurologic and psychiatric disturbances (most notably depression), and fatty deterioration of the liver, sometimes[omicsonline.org]

  • Amyloidosis

    Pedigree of Family with a PRNP Y163X Mutation Associated with Chronic Diarrhea and Autonomic Failure.[doi.org] bruising or bleeding Pancreas - Diabetes Musculoskeletal system - Joint pain or swelling, weakness Skin - Lumps or purple discoloration No one knows what causes amyloidosis[health.harvard.edu] Tafamidis is a TTR stabilizer that is orally administered and, by interfering with amyloid fibril formation and deposition, is capable of slowing progression of TTR polyneuropathy[ncbi.nlm.nih.gov]

  • Multiple Myeloma

    For this reason we report this rare case in which diarrhea and abdominal pain were the initial presenting symptoms of multiple myeloma with a plasmacytoma.[ncbi.nlm.nih.gov] bruising or bleeding – due to low platelet numbers Bleeding from the nose or gums Repeated infections or infections that are hard to get rid of Thirst, nausea, vomiting or[betterhealth.vic.gov.au] […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[radiopaedia.org]

  • Waldenstrom Macroglobulinemia

    Tests reported noninflammatory diarrhea, severe hypoalbuminemia of 1.6 g/dL, and prolonged coagulation times.[revistagastroenterologiamexico.org] The covered platelet cells may not work right, resulting in bleeding and easy bruising. Every year, there are five new cases of macroglobulinemia per 1,000,000 people.[uihc.org] Neuropathy is typically slowly progressive, distal, symmetrical, and sensorimotor.[emedicine.medscape.com]

  • Vasculitis

    Gastrointestinal Tract Abdominal pain, bloody diarrhea, perforation of the intestines.[web.archive.org] Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[neuromuscular.wustl.edu] Other concerning symptoms include trouble breathing, coughing up blood, or bloody diarrhea.[hss.edu]

  • Polyarteritis Nodosa

    The initial report describes a 23-year-old man who had a 5-day history of fever and diarrhea. Since then, the definition of PAN has evolved.[ncbi.nlm.nih.gov] […] especially the large ones Skin rash with raised reddish-purple patches and knobs that can be felt along affected arteries Stomach pain sometimes with nausea, vomiting and bloody diarrhea[cedars-sinai.edu] Tingling, burning, pain, or numbness in your feet, hands, legs, arms, and face Decreased alertness Inability to think clearly Gastrointestinal: Belly pain Nausea Vomiting Diarrhea[cancercarewny.com]

  • Whipple Disease

    Thus, it represents an important differential diagnosis of chronic diarrhea.[ncbi.nlm.nih.gov] A 58-year-old man with dizziness and unsteady gait had a 10-year history of behavioral change, impotence, and a progressive peripheral neuropathy.[ncbi.nlm.nih.gov] Signs and symptoms [ edit ] The most common symptoms are diarrhea, abdominal pain, weight loss, and joint pains.[en.wikipedia.org]

  • Secondary Amyloidosis

    TCZ may work immediately in diarrhea associated with secondary amyloidosis.[ncbi.nlm.nih.gov] bruising or bleeding Pancreas - Diabetes Musculoskeletal system - Joint pain or swelling, weakness Skin - Lumps or purple discoloration No one knows what causes amyloidosis[health.harvard.edu] […] slightly raised, waxy nodules clustered in the armpits, groin, face, neck, or ears; purple discoloration of the skin, bleeding into the skin (purpura) around the eyes and easy[healthcommunities.com]

  • Phosphorus Poisoning

    Common symptoms were gastrointestinal: abdominal pain, diarrhea, nausea and vomiting.[thepoisonreview.com] In addition, non-inflammatory degenerative disease of the sensorimotor nerves (sensorimotor polyneuropathy) may advance to progressive deterioration (atrophy).[rarediseases.org] Diarrhea was not a presenting complaint. Initial symptoms were referable to the gastrointestinal tract, central nervous system, or both.[ncbi.nlm.nih.gov]

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