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779 Possible Causes for Diarrhea, Easy Bruising, Splenomegaly

  • Alcoholic Liver Disease

    People who drink more than two alcoholic drinks per day are at risk of liver disorders, the most common symptoms of which include nausea, diarrhea, anorexia, abdominal pain[hospital.uillinois.edu] bruising accumulation of extra fluid in the legs , known as edema.[the-alcoholism-guide.org] Splenomegaly : Portal hypertension causes the spleen to enlarge (a condition called splenomegaly).[msdmanuals.com]

  • Primary Myelofibrosis

    Occasionally, patients may have diarrhea related to pressure on the colon.[emedicine.medscape.com] Easy bruising or bleeding. Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com] We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    The patient presented with an acute abdomen with clinical findings of acute cholecystitis, subileus, and local pain in the right upper abdomen accompanied by severe diarrhea[ncbi.nlm.nih.gov] Symptoms of AML include: Fever Shortness of breath Easy bruising or bleeding Bleeding under the skin Weakness or feeling tired Weight loss or loss of appetite Tests that examine[nlm.nih.gov] Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com]

  • Amyloidosis

    PATIENT CONCERNS: We reported two cases with ApoA-1 amyloidosis, a 64-year-old man suffering from nephrotic syndrome and a 40-year-old man with nephrotic syndrome and splenomegaly[ncbi.nlm.nih.gov] Pedigree of Family with a PRNP Y163X Mutation Associated with Chronic Diarrhea and Autonomic Failure.[doi.org] bruising or bleeding Pancreas - Diabetes Musculoskeletal system - Joint pain or swelling, weakness Skin - Lumps or purple discoloration No one knows what causes amyloidosis[health.harvard.edu]

  • Waldenstrom Macroglobulinemia

    Tests reported noninflammatory diarrhea, severe hypoalbuminemia of 1.6 g/dL, and prolonged coagulation times.[revistagastroenterologiamexico.org] The covered platelet cells may not work right, resulting in bleeding and easy bruising. Every year, there are five new cases of macroglobulinemia per 1,000,000 people.[uihc.org] Abstract Manifestations of macroglobulinemic lymphoma include lymphadenopathy, splenomegaly and bone marrow involvement.[ncbi.nlm.nih.gov]

  • Primary Biliary Cirrhosis

    […] of the caudate lobe hepatic surface irregularity due to regenerative nodules regional lymphadenopathy: tends to dominate in the gastrohepatic ligament and porta hepatis 4 splenomegaly[radiopaedia.org] After the pneumonia improved, she developed severe watery diarrhea. Although vancomycin was administered enterally, the diarrhea persisted.[ncbi.nlm.nih.gov] Patients may have a low platelet count because of an enlarged spleen causing easy bruising.[medicinenet.com]

  • Alcoholic Hepatitis

    Common symptoms are weakness, anorexia, weight loss, nausea, vomiting and diarrhea. Patients with alcoholic hepatitis are often malnourished and pyrexial.[euroliver.org] […] deficiency) Endocrine Gynaecomastia Testicular atrophy Loss of body hair Signs of ‘pseudo- Cushings ’ (red face, hump, striae) Face /skin Parotid enlargement Spider naevi Easy[almostadoctor.co.uk] Image studies showed an extremely enlarged fatty liver and splenomegaly.[ncbi.nlm.nih.gov]

  • Hepatitis B

    Symptoms that can occur include mild fever, headache, fatigue, loss of appetite, nausea and vomiting, diarrhea, muscle and joint pain, abdominal pain, a skin rash, and jaundice[emoryhealthcare.org] bruising and bleeding Chronic HBV infection can lead to serious liver disease, liver scarring (cirrhosis), and hepatocellular (liver) cancer.[sfcdcp.org] CASE REPORT: A 29-year-old man, with no significant prior medical history, presented with fever and massive splenomegaly.[ncbi.nlm.nih.gov]

  • Viral Hepatitis

    In older cattle bovine virus diarrhea (mucosal disease) is the major cause.[medical-dictionary.thefreedictionary.com] Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis[medlineplus.gov] The symptoms are similar to mild flu, and may include : Jaundice is a symptom of hepatitis. diarrhea fatigue loss of appetite mild fever muscle or joint aches nausea slight[medicalnewstoday.com]

  • Familial Myelofibrosis

    Because platelets play an essential role in homeostasis, thrombocytopenia results in easy bruising and a propensity to bleed.[symptoma.com] Treatment Splenomegaly and extramedullary haemopoiesis Medical treatment remains the treatment of choice for most patients with symptomatic splenomegaly.[onlinelibrary.wiley.com] bruising, nosebleeds or heavy periods Gastrointestinal bleeding or blood in the urine Thrombotic complications can also occur, resulting in: Stroke Transient ischemic attack[mpnresearchfoundation.org]

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