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442 Possible Causes for Diarrhea, Easy Bruising, Thrombocytosis

  • Celiac Disease

    The patient's diarrhea resolved after initiation of a gluten free diet. He gained 25 kilograms after discharge and did not require further hospitalizations for diarrhea.[ncbi.nlm.nih.gov] bruising Depression or anxiety Fatigue Growth delay in children Hair loss Itchy skin with a rash ( dermatitis herpetiformis ) Missed menstrual periods Mouth ulcers Muscle[nlm.nih.gov] Nelson EW, Ertan A, Brooks FP, et al: Thrombocytosis in patients with celiac sprue. Gastroenterology 1976;70:1042-1044.[dx.doi.org]

  • Primary Myelofibrosis

    Occasionally, patients may have diarrhea related to pressure on the colon.[emedicine.medscape.com] Easy bruising or bleeding. Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com] Objectives: To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET).[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    The patient presented with an acute abdomen with clinical findings of acute cholecystitis, subileus, and local pain in the right upper abdomen accompanied by severe diarrhea[ncbi.nlm.nih.gov] Symptoms of AML include: Fever Shortness of breath Easy bruising or bleeding Bleeding under the skin Weakness or feeling tired Weight loss or loss of appetite Tests that examine[nlm.nih.gov] Here we report a case of AML with thrombocytosis arising in a patient with this syndrome.[ncbi.nlm.nih.gov]

  • Amyloidosis

    Pedigree of Family with a PRNP Y163X Mutation Associated with Chronic Diarrhea and Autonomic Failure.[doi.org] bruising or bleeding Pancreas - Diabetes Musculoskeletal system - Joint pain or swelling, weakness Skin - Lumps or purple discoloration No one knows what causes amyloidosis[health.harvard.edu] Thrombocytosis is a diagnostic clue and occurs in 10%. Reduced renal function is present at diagnosis in 50% of patients.[circ.ahajournals.org]

  • Familial Myelofibrosis

    Because platelets play an essential role in homeostasis, thrombocytopenia results in easy bruising and a propensity to bleed.[symptoma.com] […] lymphoid neoplasms or other malignancy Minor criteria: Leukoerythroblastosis Increased serum LDH (lactate dehydrogenase) Anemia Splenomegaly Laboratory Anemia, leukocytosis, thrombocytosis[pathologyoutlines.com] bruising, nosebleeds or heavy periods Gastrointestinal bleeding or blood in the urine Thrombotic complications can also occur, resulting in: Stroke Transient ischemic attack[mpnresearchfoundation.org]

  • Whipple Disease

    Thus, it represents an important differential diagnosis of chronic diarrhea.[ncbi.nlm.nih.gov] Regarding laboratory findings, hypochromic anemia, limphocytopenia, thrombocytosis, increased C-reactive protein levels, vitamin deficiency, or indirect signs of malabsorption[scielo.isciii.es] Signs and symptoms [ edit ] The most common symptoms are diarrhea, abdominal pain, weight loss, and joint pains.[en.wikipedia.org]

  • Phosphorus Poisoning

    Diarrhea was not a presenting complaint. Initial symptoms were referable to the gastrointestinal tract, central nervous system, or both.[ncbi.nlm.nih.gov] Common symptoms were gastrointestinal: abdominal pain, diarrhea, nausea and vomiting.[thepoisonreview.com] Frequent symptoms after ingestion are nausea, vomiting, abdominal cramps, diarrhea, and hypotension. Patients typically deteriorate rapidly and enter a coma.[symptoma.com]

  • Henoch-Schönlein Purpura

    In addition to the abdominal pain, he developed diarrhea and colonic biopsy findings were suggestive of inflammatory bowel disease (IBD).[ncbi.nlm.nih.gov] There is evidence of bleeding under the skin, with easy bruising and the development of petechiae.[medical-dictionary.thefreedictionary.com] […] have been reported include esophageal stenosis, hemorrhagic pancreatitis, protein-losing enteropathy, pulmonary function abnormalities, pulmonary and pleural hemorrhage, thrombocytosis[jasn.asnjournals.org]

  • Non-Hodgkin Lymphoma

    […] frequently reported ( 20%) adverse events of any grade in the population in which safety was studied were hyperglycemia, fatigue, and nausea (36.1% each), depression (29.2%), diarrhea[ncbi.nlm.nih.gov] Symptoms may include: Lymph node enlargement Fever Night sweats and/or chills Fatigue Unexplained weight loss Nausea and vomiting Easy bruising or bleeding Frequent infections[cancercenter.com] In the first case, the laboratory tests showed anemia, thrombocytosis, elevated inflammatory biomarkers, a low level of iron, and hypoproteinemia.[ncbi.nlm.nih.gov]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Common non-hematologic adverse events (AEs) were diarrhea (95 %), rash (57 %), and nasopharyngitis (51 %).[ncbi.nlm.nih.gov] Here we report a case of coexistence of BCR-ABL1 fusion gene and CALR mutation, diagnosed due to persistent thrombocytosis while the patient was in treatment-free, complete[sci.amegroups.com] The most frequent side effect was diarrhea, however, this did not result in any patient discontinuations.[empr.com]

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