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193 Possible Causes for Diarrhea, Fever, Peripheral T Cells Decreased

  • Adenovirus Infection

    Enteric viral infectious should be considered in solid organ transplant recipients with chronic diarrhea.[ncbi.nlm.nih.gov] […] period of 1-14 days, whereas rhinitis, fever, and cervical lymphadenopathy are typical for pharyngoconjunctival fever (PCF).[symptoma.com] Appearance of virus-specific CD4 T cells in peripheral blood and a rise of neutralizing antibody titres specific for the HAdV serotype infecting the patient could be demonstrated[nature.com]

  • HIV Infection

    METHODS: The Global Enteric Multicenter Study enrolled children with moderate-to-severe diarrhea (MSD) and less-severe diarrhea (LSD) between December 2007 and November 2012[ncbi.nlm.nih.gov] […] case reports about drug fever due to piperacillin/tazobactam with other comorbidities.[ncbi.nlm.nih.gov] Highly active antiretroviral therapy results in a decrease in CD8 T cell activation and preferential reconstitution of the peripheral CD4 T cell population with memory rather[hivinsite.ucsf.edu]

  • Graves Disease

    Though quite rare, this disease can also manifest with gastrointestinal symptoms such as dysphagia, heartburn, nausea, vomiting and diarrhea.[ncbi.nlm.nih.gov] A 61 years old woman presented with low grade fever and weight loss for a month.[ncbi.nlm.nih.gov] Notably, HLA-DR14, a known risk factor for GD in Japanese individuals and the decreased regulatory T-cell numbers that were seen in the pediatric case, may affect the early[ncbi.nlm.nih.gov]

  • Graft-versus-Host-Disease

    One male kidney transplant recipient developed diarrhea and suffered kidney function damage.[ncbi.nlm.nih.gov] The clinical findings mainly include high fever, cytopenia, splenomegaly, phagocytosis, and proliferation of histiocytes in lymphoreticular tissue.[ncbi.nlm.nih.gov] These cells induce allogeneic T cell death in response to interferon-γ, resulting in regulatory T cell expansion and immunosuppression.[stm.sciencemag.org]

  • Acquired Immunodeficiency Syndrome

    […] recent CD4 count, four months before admission, was 19) and hepatitis C who presented to the Emergency Department complaining of one week of persistent nausea, vomiting, and diarrhea[ncbi.nlm.nih.gov] Pneumocystis carinii and fever improved immediately when ST mixture and highly active antiretroviral therapy (HAART) were performed.[ncbi.nlm.nih.gov] Monoclonal antibody analysis of peripheral-blood T-cell subsets revealed a marked decrease of the T-helper cell subset with inversion of the normal ratio of T-helper to T-suppressor[cdc.gov]

  • Behçet Disease

    […] genital (67%) ulcers, arthralgia or arthritis (42%), skin involvement (53%) such as erythema nodosum or abdominal symptoms (60%) such as abdominal pain, digestive ulcers or diarrhea[ncbi.nlm.nih.gov] The addition of serum from active BD patients to that of healthy controls increased the frequency of Th17 and Th1 cells and decreased FoxP3 expression in CD4 T cells.[doi.org] […] vomiting, 9 vs. 1; and diarrhea, 12 vs. 2).[nejm.org]

  • Reiter's Syndrome

    In some cases, lymphocyte phenotyping reveals abnormal (activated) T-cell subsets (CD4 T cells with decreased or absent expression of surface CD3).[ncbi.nlm.nih.gov] Two cases of Reiter's syndrome triggered by travelers' diarrhea are presented.[ncbi.nlm.nih.gov] A 32-year-old Japanese man developed polyarthritis with mild fever and conjunctivitis.[ncbi.nlm.nih.gov]

  • Severe Combined Immunodeficiency

    Both patients presented similar signs and symptoms (fever, skin rash, diarrhea, pancytopenia, and icterus). Skin biopsies demonstrated Grade II GVHD involvement.[ncbi.nlm.nih.gov] Peripheral tolerance is also markedly decreased in SCID because of several factors including the expansion of T-cell clones as a consequence of the lymphopenia observed in[link.springer.com] Herein, we present a five-month-old boy with SCID who was referred to our center with recurrent diarrhea, respiratory infection and lymphadenopathy.[ncbi.nlm.nih.gov]

  • Influenza

    In contrast, IL-1R1 / mice showed a dramatic decrease in CD4 T-cell proliferation, suggesting that efficient T-helper cell priming in peripheral organs is dependent on a functional[doi.org] It is a syndrome encompassing an onset of high fever, disturbance of consciousness, convulsion, and shock that rapidly progresses to watery diarrhea and liver and renal dysfunctions[ncbi.nlm.nih.gov] Miller, Acute Fever and Petechial Rash Associated with Influenza A Virus Infection, Clinical Infectious Diseases, Volume 29, Issue 2, 15 July 1999, Pages 453–454, Download[doi.org]

  • Food Allergy

    This causes low FOXP3 mRNA levels and markedly decreased protein expression in peripheral blood lymphocytes of affected patients.[ncbi.nlm.nih.gov] Two infants with AE, diarrhea, and low serum zinc levels were evaluated. Food allergy was found in both infants. The first infant had a serum IgE level of 4642 IU/mL.[ncbi.nlm.nih.gov] Other flaviviruses include those that cause dengue, yellow fever, and West Nile fever.[niaid.nih.gov]

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