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1,973 Possible Causes for Diarrhea, Pancytopenia

  • Graft-versus-Host-Disease

    CLINICAL FINDINGS: One male kidney transplant recipient developed diarrhea and suffered kidney function damage.[ncbi.nlm.nih.gov] All cases had diarrhea and pancytopenia, 4 out of 5 presented with erythematous skin rashes, and 2 had cytomegalovirus colitis.[ncbi.nlm.nih.gov] The patient had dehydration, acute kidney injuries, rashes, diarrhea, and pancytopenia.[ncbi.nlm.nih.gov]

  • Colchicine

    Diarrhea led to discontinuation of colchicine in 23 (52%) of the 44 patients.[ncbi.nlm.nih.gov] The patient's clinical manifestations included abdominal cramps, vomiting, pancytopenia, hypocholesterolemia, and rhabdomyolysis.[ncbi.nlm.nih.gov] She developed acute renal and liver failure, acute lung injury, pancytopenia with sepsis, rhabdomyolysis, hypertriglyceridemia, and ultimately died on Day 14 from hyperammonemic[ncbi.nlm.nih.gov]

  • Systemic Mastocytosis

    CASE REPORT: A 41-year-old woman presented with a three-year history of fatigue, occasional diarrhea, mild fever, skin rash and splenomegaly.[ncbi.nlm.nih.gov] The disease progressed rapidly and severe pancytopenia and recurrent upper gastrointestinal bleeding became the dominant problem.[ncbi.nlm.nih.gov] The most common grade 3/4 nonhematologic drug-related AEs were diarrhea (6.6 %) and headache (4.9 %).[ncbi.nlm.nih.gov]

  • Acute Radiation Sickness

    For example, damage to the GI is scored by evaluating the time of onset, severity, the frequency of vomiting or diarrhea.[symptoma.com] During the latent period for this type, the lymph nodes, spleen and bone marrow begin to atrophy, leading to underproduction of all types of blood cells (pancytopenia).[rarediseases.org] […] doses cause initial anorexia, lethargy and vomiting then normality for several weeks followed by vomiting, nasal discharge, dysentery, recumbency, septicemia and a profound pancytopenia[medical-dictionary.thefreedictionary.com]

  • Acute Arsenic Poisoning

    Full metabolic panel: There may be electrolyte derangements due to vomiting and diarrhea.[symptoma.com] […] and be reversible; may have nonspecific clinical presentation of pancytopenia, fatigue / weakness (anemia), frequent infections (leukopenia) and easy bruising / petechia[pathologyoutlines.com] With severe diarrhea serious salt and water loss usually occurs; this leads to shock, kidney failure, coma and respiratory paralysis.[dmsachelation.com]

  • Fluorouracil

    Furthermore, HST reduced 5-FU-induced diarrhea development.[ncbi.nlm.nih.gov] Because of pancytopenia, DPYD enzyme activity could not be assessed in patient 2; genotypic analysis of DPYD during autopsy revealed the presence of the heterozygous mutation[ncbi.nlm.nih.gov] Blood and lymphatic system disorders: Very common: Myelosuppression (leucopenia, pancytopenia and thrombocytopenia); agranulocytosis, anaemia Immune system disorders: Rare[medicines.org.uk]

  • Aggressive Systemic Mastocytosis

    Patients present with severe symptoms related to mast cell invasion and the intense release of mediators including syncope, recurrent flushing, diarrhea, pain, organomegaly[orpha.net] Because mast cells release histamine, ASM is also associated with histamine-mediated symptoms like flushing, skin itching, nausea, vomiting, diarrhea, and anaphylaxis.[symptoma.com] […] organomegaly and organ dysfunction, impairment of hematopoietic function (which may result in disruption of the blood count ranging from isolated cytopenia to more or less marked pancytopenia[orpha.net]

  • Primary Myelofibrosis

    Occasionally, patients may have diarrhea related to pressure on the colon.[emedicine.medscape.com] This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com] Besides abdominal swelling, other symptoms such as digestive disorders (diarrhea and constipation) heartburn, and indigestion triggered by fatty foods may also appear.[aoporphan.com]

  • Chronic Arsenic Poisoning

    His vomiting and diarrhea would be bloody and his abdominal pain severe. With an acute poisoning, death can take many hours and is not pleasant.[writersforensicsblog.wordpress.com] […] and be reversible; may have nonspecific clinical presentation of pancytopenia, fatigue / weakness (anemia), frequent infections (leukopenia) and easy bruising / petechia[pathologyoutlines.com] With severe diarrhea serious salt and water loss usually occurs; this leads to shock, kidney failure, coma and respiratory paralysis.[dmsachelation.com]

  • HIV Infection

    METHODS: The Global Enteric Multicenter Study enrolled children with moderate-to-severe diarrhea (MSD) and less-severe diarrhea (LSD) between December 2007 and November 2012[ncbi.nlm.nih.gov] […] osteomalacia* Protease inhibitors with statins: myopathy Hematologic or oncologic Anemia of chronic disease Lymphoma, multiple myeloma Bone marrow infiltration (leading to pancytopenia[aafp.org] Pancytopenia is not uncommon in advanced AIDS and bone marrow biopsies often reveal evidence of hypoplasia.[hivinsite.ucsf.edu]

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