Diastolic Murmur & Eisenmenger Syndrome & Pulmonary Systolic Murmur: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Diastolic Murmur, Eisenmenger Syndrome, Pulmonary Systolic Murmur,

Negated

None

Unsure

None

Possible Causes

Patent Ductus Arteriosus

The patient was a 19-year-old woman who was diagnosed with patent ductus arteriosus complicating Eisenmenger syndrome at a previous medical institution. [ncbi.nlm.nih.gov]

In patients with a large left-to-right shunt, a low-pitched mitral mid-diastolic murmur may be audible at the apex. [medicaljoyworks.com]

Course and Complications  Ejection systolic murmur at birth (due to pulmonary hypertension)  continuous murmur after a few weeks  Development of Pulmonary arterial hypertension [slideshare.net]

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Eisenmenger Syndrome

syndrome fetal heart defect Eisenmenger's reaction tardive cyanosis ES Eisenmenger syndrome Eisenmenger's Syndrome Statements Identifiers Sitelinks Wikipedia (17 entries) [wikidata.org]

murmur pulmonary insufficiency jugular venous distension loud pulmonary component of S2 sound clubbing of extremities peripheral edema Imaging Radiography indication performed [step2.medbullets.com]

Along the left sternal border systolic murmur can be heard, and early pulmonary systolic shock. [remedyland.com]

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Large Ventricular Septal Defect

syndrome. [ncbi.nlm.nih.gov]

A smaller defect will lead to a louder murmur Diastolic murmur : Diastolic rumble due to increased flow across mitral valve due to left-to right shunting. [pedclerk.bsd.uchicago.edu]

loudest at the fourth intercostal space, usually with a thrill, and a loud and widely split pulmonic component of S2 With fixed pulmonary hypertension, diastolic murmur [quizlet.com]

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Left to Right Cardiac Shunt

Mortality Patients with Eisenmenger syndrome usually do not survive beyond the second or third decade. [emedicine.medscape.com]

Auscultatory findings Harsh h olosystolic murmur over the left lower sternal border ; typically louder in small defects Mid- diastolic murmur over cardiac apex Systolic thrill [amboss.com]

A large left-to-right atrial shunt may produce a rumbling low-pitched diastolic murmur (due to increased tricuspid flow) at the lower sternal borders. [merckmanuals.com]

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Lutembacher Syndrome

Eisenmenger's syndrome (very uncommon with a large atrial septal defect (ASD) and a high left atrial pressure due to the mitral stenosis). [patient.info]

A loud mid diastolic murmur from the left sternal border to the apex without presystolic accentuation was heard. [jscisociety.com]

There was an ejection systolic murmur over the pulmonary area with no radiation or respiratory variation. [hindawi.com]

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Pulmonary Valve Disease

[…] defect ( Ostium primum ) - Tetralogy of Fallot - Eisenmenger's syndrome Right: pulmonary and tricuspid valves pulmonary valves ( stenosis, insufficiency ) - tricuspid valves [wikidoc.org]

The pulmonary regurgitation, especially if severe and caused by pulmonary hypertension, causes a high-pitched diastolic murmur that might be misinterpreted as aortic regurgitation [symptoma.com]

Signs Soft pulmonary systolic murmurs are more easily heard with the patient lying down. [patient.info]

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Ostium Primum Atrial Septal Defect

Cyanosis only appears once Eisenmenger syndrome has developed especially if there is no concomitant pulmonary stenosis. [symptoma.com]

Murmurs • Pulmonary ejection systolic murmur – Increased pulmonary flow • Tricuspid murmur – is heard over left sternal edge louder on inspiration • Graham-Steell murmur [slideshare.net]

Eisenmenger syndrome. Pulmonary hypertension can cause permanent lung damage. [mayoclinic.org]

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Congenital Heart Disease

The highest risk category was Eisenmenger syndrome, with an incidence of 4.8 deaths/1000py. [ncbi.nlm.nih.gov]

This murmur is 2-toned, having a more pronounced sound during systole (when driven by higher pressure) than during diastole. [merckmanuals.com]

syndrome and severe pulmonary arterial hypertension Management of cyanotic patients References [escardio.org]

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Right Ventricular Outflow Obstruction

Single lung transplantation and closure of patent ductus arteriosus for Eisenmenger's syndrome. J Thorac Cardiovasc Surg 1990 ; 100 : 1 – 5. 2. [cambridge.org]

murmur at the left parasternal margin. [revespcardiol.org]

Examination revealed an ejection systolic murmur in the pulmonary area. The electrocardiogram showed complete heart block. [onlinejacc.org]

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Acyanotic Congenital Heart Disease

’s Syndrome if a large lesion is not detected and treated early enough 3 Common Stenotic Lesions Pulmonary stenosis (PS) Aortic stenosis (AS) Coarctation of the aorta (CoA [slideplayer.com]

murmur loud pan-systolic murmur heard throughout precordium -- radiates to axilla collapsing pulse, displaced apex, soft early diastolic murmur left sternal edge 6 common [cram.com]

[…] aorta -Pulmonary stenosis systolic murmur common -RVH "Tet" spell is associated with what and does it look like? [quizlet.com]

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Ventricular Septal Defect

This can cause a condition called Eisenmenger's syndrome. [ucsfhealth.org]

There is further turbulent flow into the left ventricle from the left atrium causing the diastolic murmur. [easyauscultation.com]

Making the diagnosis A systolic ejection murmur may be heard in the pulmonary area due to increased flow across the pulmonary valve (relative pulmonary stenosis). [utmb.edu]

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Atrial Septal Defect Type Ostium Primum

Cyanosis can present in the setting of elevated pulmonary artery pressure, as in Eisenmenger syndromes having a poor prognosis. [j-pcs.org]

A large left-to-right atrial shunt may produce a low-pitched diastolic murmur (due to increased tricuspid flow) at the left lower sternal border. [babiesonline.co.za]

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Persistent Truncus Arteriosus

In this image focus, we describe the case an old woman with persistent unrepaired truncus arteriosus type III and Eisenmenger syndrome. [ncbi.nlm.nih.gov]

A mid-diastolic mitral flow murmur may be audible at the apex when pulmonary blood flow is increased. [checkorphan.org]

Auscultation is completed by a mild or intense systolic murmur along the left sternal border. A mid-diastolic mitral flow murmur can also be noted. [symptoma.com]

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Atrial Septal Defect 9

Eisenmenger syndrome. Pulmonary hypertension can cause permanent lung damage. [mayoclinic.org]

Mid diastolic murmur due to relative tricuspid stenosis was detected in most cases (75%). [paediatricaindonesiana.org]

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Atrial Septal Defect

Eisenmenger syndrome. Pulmonary hypertension can cause permanent lung damage. [mayoclinic.org]

There is a brief diamond shaped murmur in early systole and another brief diamond shaped murmur in early diastole In the anatomy tab you see an enlarged right atrium and right [easyauscultation.com]

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Ostium Secundum Atrial Septal Defect

This phenomenon is known as Eisenmenger's syndrome. [marmur.com]

A large left-to-right atrial shunt may produce a low-pitched diastolic murmur (due to increased tricuspid flow) at the left lower sternal border. [babiesonline.co.za]

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Acquired Ventricular Septal Defect

This influences the occurrence of pulmonary vascular disease or Eisenmenger’s syndrome. [lecturio.com]

[…] loudest at the left sternal border, often accompanied by a palpable thrill; mid-diastolic apical rumble due to flow across the mitral valve; decrescendo diastolic murmur [medical-dictionary.thefreedictionary.com]

Qp/Qs is 2 and there is evidence of volume overload of the LV Acute VSD after myocardial infarction If Eisenmenger’s syndrome is present, closure of a VSD is NOT recommended [healio.com]

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Cor Triloculare Biventriculare

Anesthetic methods and the management of patients with Eisenmenger syndrome are challenging. [bmcanesthesiol.biomedcentral.com]

Cor triloculare biventriculare, single atrium includes a diastolic murmur. Click here to compare your answer. [hospitalphysician.com]

Survival to adulthood is expected in most patients with pulmonary valves with systolic ejection murmurs and wide splitting of the second heart sound. [studyres.com]

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Pulmonary Atresia

Abstract Management of patients with Eisenmenger syndrome with pulmonary atresia is challenging because of the complexity of the structure-function relationship of the components [ncbi.nlm.nih.gov]

In some patients with severe cyanosis, no murmur can be heard. An early diastolic murmur of aortic regurgitation may be noted. [emedicine.com]

Auscultatory finding: harsh systolic murmur that is best heard over Erb's point and left upper sternal border ; single second heart sound Diagnostics Pulse oximetry : SpO2 [amboss.com]

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Cor Pulmonale

syndrome I27.89 Other specified pulmonary heart diseases I27.9 Pulmonary heart disease, unspecified I28 Other diseases of pulmonary vessels I28.0 Arteriovenous fistula of [icd10data.com]

murmur. [slideshare.net]

Split second heart sound with loud pulmonary component. Systolic ejection murmur with a sharp ejection click over the pulmonary artery (advanced sign). [patient.info]

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Acute Aortic Regurgitation

[…] defect ( Ostium primum ) - Tetralogy of Fallot - Eisenmenger's syndrome Right: pulmonary and tricuspid valves pulmonary valves ( stenosis, insufficiency ) - tricuspid valves [wikidoc.org]

Early closure of the mitral valve, weak first heart sound, tall A wave of apexcardiogram, and early diastolic murmur indicated acute aortic regurgitation. [ncbi.nlm.nih.gov]

An early systolic murmur and a diastolic blowing murmur with thrill were detected at the left parasternal border. [kjim.org]

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Pulmonary Valve Insufficiency

syndrome アイゼンメンジャー症候群 ejection fraction (EF)駆出分画（率） ejection time (ET)駆出時間 electrical alternans電気的交互脈 electrocardiogram (ECG) 心電図 electrocardiography 心電［図］学（法） electrode電極 [tokyo-med.ac.jp]

[…] on chronic hemodialysis with a diastolic murmur (group A), 26 patients on chronic hemodialysis without murmurs (group B), and 15 healthy persons (group C). [annals.org]

Signs Soft pulmonary systolic murmurs are more easily heard with the patient lying down. [patient.info]

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Endocardial Cushion Defect

Eisenmenger’s syndrome and pregnancy. [ncbi.nlm.nih.gov]

and sometimes a diastolic murmur at the apex and low left sternal border (see table Heart Murmur Intensity ). [merckmanuals.com]

A systolic murmur of a ventricular septal defect can be heard as well as the systolic murmur of mitral insufficiency. [chdbabies.com]

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Heart Murmur

Longstanding uncorrected atrial septal defects can also result in Eisenmenger's syndrome with resultant cyanosis. [en.wikipedia.org]

[…] pansystolic murmur Machinery murmur Mid-diastolic mitral murmur Mid-diastolic murmur Mid-diastolic tricuspid murmur Mid-systolic murmur Mitral late systolic murmur Multiple [icd9data.com]

Most murmurs are systolic and location of a systolic murmur can point toward specific cardiac diagnosis as described in the table below: Upper left sternal border Pulmonary [patient.info]

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Pulmonary Valve Stenosis

Examples of such syndromes involving stenosis of the pulmonic valves are Holt-Oram syndrome, Noonan syndrome, and Leopard syndrome. [5, 7] Eisenmenger syndrome associated [emedicine.com]

Soft diastolic murmur at the left upper sternal edge. Right ventricular hypertrophy. Loud P2 (pulmonary component of the second heart sound). [patient.info]

Sixteen patients were asymptomatic with pulmonary systolic murmurs, although 6 patients presented with dyspnea. [ncbi.nlm.nih.gov]

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Pulmonary Hypertension

Since the introduction of targeted therapies in Eisenmenger's syndrome, there is growing interest in pre-Eisenmenger's syndrome patients considered inoperable on the basis [doi.org]

diastolic murmurs, opening snap, and gallop Congenital or acquired heart or valvular disease Rales, dullness, or decreased breath sounds Pulmonary congestion or effusion [doi.org]

Clinical signs include right ventricular (parasternal) heave, a loud pulmonary second heart sound, murmur of pulmonary regurgitation, systolic murmur of tricuspid regurgitation [patient.info]

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Mitral Valve Atresia

Eisenmenger Syndrome Heterotaxy Syndrome Holt-Oram Syndrome Hunter Syndrome Hurler Syndrome HCM Hypertrophic Cardiomyopathy Hypoplastic Ascending Aorta HLHS Hypoplastic Left [savinglittlehearts.com]

Clinical examination classically reveals a malar flush ('mitral facies') due to cutaneous vasoconstriction, and a mid-diastolic murmur that is heard on praecordial auscultation [radiopaedia.org]

In the absence of pulmonary hypertension, the murmur is usually low-intensity and early systolic. [patient.info]

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Aortic Valve Disorder

syndrome, hyperthyroidism, and pulmonary stenosis. [en.wikipedia.org]

[…] systolic murmur (crescendo-decrescendo) early diastolic murmur Additional features soft S 2 Austin Flint murmur Investigations A thorough history and clinical examination [gponline.com]

QUESTION: Will the murmur in mitral insufficency (regurgitation) occur during systole or diastole? [courses.washington.edu]

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Tricuspid Valve Disease

syndrome pulmonary stenosis pulmonary regurgitation hyperthyroidism Plain radiograph Signs of tricuspid regurgitation on chest radiograph are often subtle, but include 6 [radiopaedia.org]

The lesion itself produces a low rumbling diastolic murmur, often accompanied by that of a tricuspid regurgitation, which is high-pitched and pansystolic. [symptoma.com]

In the absence of pulmonary hypertension, the murmur is usually low-intensity and early systolic. [patient.info]

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Heart Valve Disease

syndrome, hyperthyroidism, and pulmonary stenosis. [en.wikipedia.org]

Murmurs which occur when the heart contracts (squeezes) are called systolic murmurs and those that occur when the heart relaxes are called diastolic murmurs. [irishheart.ie]

Late systolic murmurs are typical of MV prolapse or papillary muscle dysfunction. [ncbi.nlm.nih.gov]

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