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3,236 Possible Causes for Difficulty closing both Eyelids, Facial Muscle Weakness and Progressive Atrophy, Limb Weakness

  • Facioscapulohumeral Muscular Dystrophy

    Facioscapulohumeral muscular dystrophy is an autosomal-dominant, slowly progressive myopathy that involves facial, shoulder, and upper arm muscles.[ncbi.nlm.nih.gov] FSHD presentation with foot drop or lower limb proximal weakness appeared to be more frequent than expected.[ncbi.nlm.nih.gov] FSHD affects about one in 20-400,000 people, and no effective therapeutic strategies are known to halt disease progression or reverse muscle weakness or atrophy.[ncbi.nlm.nih.gov]

  • Lambert Eaton Myasthenic Syndrome

    Here, we describe a patient with a 5-year history of cervical myelopathy who presented with recurrent limb weakness of her limbs and complained of recent progressive weakness[ncbi.nlm.nih.gov] MuSK MG should be considered if there is facial or tongue weakness with atrophy, or weakness that predominates in neck or shoulder muscles.[docksci.com] Neurological examination revealed muscle weakness, predominantly in the proximal parts of the limbs.[ncbi.nlm.nih.gov]

  • Myasthenia Gravis

    […] turning both eyes inward when looking at an object at close range.[eyehealthweb.com] Although our patient presented all the diagnostic criteria of MG, the markedly asymmetric limb weakness presented in previous history and clinical examination of admission[ncbi.nlm.nih.gov] Limb weakness is usually more significant in the arms than in the legs.[mdedge.com]

    Missing: Facial Muscle Weakness and Progressive Atrophy
  • Muscular Dystrophy

    Abstract Facioscapulohumeral muscular dystrophy is an autosomal-dominant, slowly progressive myopathy that involves facial, shoulder, and upper arm muscles.[ncbi.nlm.nih.gov] The symptoms of FSH dystrophy may appear during childhood with severe facial and limb weakness or develop slowly and gradually in adulthood with progressive difficulty closing[kennedykrieger.org] Later on, after many years, mild limb weakness around the shoulders and hips may also develop.[patient.info]

    Missing: Difficulty closing both Eyelids
  • Bell's Palsy

    Prominent among these are the inability to close the eyelids and abnormal facial appearance, with concomitant difficulty in eating, drinking and speaking.[ncbi.nlm.nih.gov] Links have been found between migraine and facial and limb weakness. A study carried out in 2015 found that people with migraine may have a higher risk of Bell's palsy.[medicalnewstoday.com] […] paresthesias, ipsilateral limb weakness, and a sense of clumsiness" that are "unexplained by facial nerve dysfunction".[13] Cause[edit] Facial nerve: the facial nerve's nuclei[en.wikipedia.org]

    Missing: Facial Muscle Weakness and Progressive Atrophy
  • Multifocal Motor Neuropathy

    In the first patient the symptoms were slowly progressive with bulbar muscle impairment, generalized weakness, muscular atrophy with cramps and fasciculations.[moh-it.pure.elsevier.com] The initial high-dose intravenous immunoglobulin treatment significantly improved left upper limb muscle weakness.[ncbi.nlm.nih.gov] Multifocal motor neuropathy is a disorder characterized by slowly progressive asymmetrical limb weakness and multiple motor conduction blocks.[ncbi.nlm.nih.gov]

    Missing: Difficulty closing both Eyelids
  • Motor Neuron Disease

    Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] Selective distal upper limb muscle weakness and atrophy with non-significant lower limb weakness during follow-up was the most frequent motor pattern, present in 18 patients[ncbi.nlm.nih.gov] Diagnostic pointers in limb-onset MND [ 1 ] Asymmetrical distal weakness frequently occurs. Brisk reflexes will occur in a wasted limb.[patient.info]

    Missing: Difficulty closing both Eyelids
  • Facial Nerve Paralysis of the Newborn

    The line between weakness and paralysis is not absolute. A condition causing weakness may progress to paralysis.[medical-dictionary.thefreedictionary.com] On the other hand, strength may be restored to a paralyzed limb. Nerve regeneration or regrowth is one way in which strength can return to a paralyzed muscle.[medical-dictionary.thefreedictionary.com]

    Missing: Facial Muscle Weakness and Progressive Atrophy
  • Adult Spinal Muscular Atrophy

    Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] As the disease progresses patients may notice limb weakness starting in the pelvis or shoulders, or weakness of the facial and tongue muscles.[cedars-sinai.edu] weakness, hypotonia Bulbar palsy Late Microcephaly Oculomotor defects: strabismus, nystagmus, oculomotor apraxia Cognitive defects Life expectancy 1 year Diagnostics Genetic[amboss.com]

    Missing: Difficulty closing both Eyelids
  • Spinal Muscular Atrophy Type 1

    Symptoms include tremors of the hands, muscle cramps, limb weakness, and twitching.[healthline.com] We present a baby with spinal muscular atrophy type 1, an inherited disorder causing progressive weakness, leading to complete paralysis of respiratory, facial and limb muscles[ncbi.nlm.nih.gov] As the disease progresses patients may notice limb weakness starting in the pelvis or shoulders, or weakness of the facial and tongue muscles.[cedars-sinai.edu]

    Missing: Difficulty closing both Eyelids

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