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17 Possible Causes for Difficulty Raising Arms, Muscle Biopsy Abnormal, Weakness after Climbing Stairs

  • Muscular Dystrophy

    This condition is typically characterized by large and abnormally distributed mitochondria on muscle biopsy, which can distinguish this condition from the other muscle conditions[ncbi.nlm.nih.gov] ; Shoulder blades that “wing” out; Difficulty raising arm above shoulder height; Foot drop (foot dorsiflexion weakness); Weak lower abdominal muscles, “pregnant” belly; Loss[fshsociety.org] Under the microscope, the muscle of a positive biopsy generally shows dead tissue and abnormally large muscle fibers.[cedars-sinai.edu]

  • Polymyositis

    Muscle biopsy abnormalities at some time during their disease: i. degeneration and regeneration of muscle fibers ii. necrosis iii. phagocytosis iv. interstitial mononuclear[clinicaltrials.gov] SYMPTOMS Proximal muscle weakness of both upper and lower limbs causes Difficulty in raising arms,lifting objects and combing hairs Difficulty in climbing and descending[de.slideshare.net] & have to be careful on stairs & ladders (don't tell the Professors who are looking after me that I climb ladders) They know.I am very positive & determined not to let it[steadyhealth.com]

  • Becker Muscular Dystrophy

    Electromyography was abnormal in all patients. Muscle biopsy in 1 patient demonstrated normal immunostaining for dystrophin.[ncbi.nlm.nih.gov] Muscle weakness in the shoulders, upper arms, upper back, and lower legs Difficulty raising the arms or lifting objects because of muscle weakness in the shoulders and back[webmd.com] As time goes by, there may be muscle weakness which causes difficulty with running, climbing stairs or walking long distances.[treat-nmd.eu]

  • Limb-Girdle Muscular Dystrophy

    Muscle biopsy abnormalities in two individuals very early in the course of their disease suggest that biopsy would probably be useful in detection of preclinical disease in[pediatrics.aappublications.org] The person may experience muscle weakness in their shoulders that makes it difficult to raise their arms above their head, hold their arms outstretched, or carry objects which[disabled-world.com] She began to experience proximal muscle weakness of both lower limbs without obvious inducement, which markedly increased when she climbed the stairs or stood up after squatting[ncbi.nlm.nih.gov]

  • Polymyalgia Rheumatica

    Microscopic and laboratory examination of muscle tissue samples (biopsy) from affected individuals does not usually reveal any muscle abnormality.[rarediseases.org] raising arms above one's head (0.19 (0.10-0.28)) were all associated with increased functional impairment.[ncbi.nlm.nih.gov] Muscle biopsy is recommended in patients with inflammatory myositis. How is PMR treated? Glucocorticoids are the mainstay of therapy for patients diagnosed with PMR.[news-medical.net]

  • Dermatomyositis

    Muscle biopsy abnormalities at some time during their disease: i. degeneration and regeneration of muscle fibers ii. necrosis iii. phagocytosis iv. interstitial mononuclear[clinicaltrials.gov] Symptoms The muscle weakness may appear suddenly or develop slowly over weeks or months. may have difficulty raising arms over head, rising from a sitting position, and climbing[slideshare.net] Running, climbing stairs, sitting from a lying position or standing from a seated position may become difficult.[arthritis.org]

  • Childhood Dermatomyositis

    The subsequent list, derived from the first survey, comprised MRI abnormalities suggestive of inflammatory myositis; calcinosis; changes on muscle biopsy typical of myositis[rheumatology.oxfordjournals.org] Patients may have difficulty raising their arms above their shoulders, climbing steps, or rising from a sitting position.[merckmanuals.com] Running, climbing stairs, sitting from a lying position or standing from a seated position may become difficult.[arthritis.org]

  • Myositis

    Small samples of muscle tissue show abnormalities in muscles, including inflammation, damage, and abnormal proteins.[myositis.org] Most often, myositis involves the muscles in the upper arms and thighs, which can cause difficulty raising arms above the head and rising from a chair.[columbiadoctors.org] There are many symptoms of myositis including muscle weakness, falls, tripping, trouble climbing stairs and fatigue after simple activities.[healthpartners.com]

  • Limb-Girdle Muscular Dystrophy Type 2B

    […] muscular dystrophies Typical muscle biopsy features MHC – class 1 upregulation, inflammatory infiltrate (frequently peri-vascular), peri-fascicular muscle fibre atrophy and[ped-rheum.biomedcentral.com] Weak shoulder muscles can make it difficult to raise arms above the head, hold the arms outstretched, or carry heavy objects.[mda.org.au] She began to experience proximal muscle weakness of both lower limbs without obvious inducement, which markedly increased when she climbed the stairs or stood up after squatting[ncbi.nlm.nih.gov]

  • Granulomatous Myositis

    In muscle biopsies, abnormal staining for the dystrophin complex can distinguish the muscular dystrophies from other forms of myopathy.[rheumatologyadvisor.com] Most often, myositis involves the muscles in the upper arms and thighs, which can cause difficulty raising arms above the head and rising from a chair.[columbiadoctors.org] Muscle biopsy reveals inclusion bodies i.e. rimmed vacuoles formed due to the collection of abnormal proteins.[kenhub.com]