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117 Possible Causes for Difficulty Rising from a Squatting Position, Muscle Biopsy showing Inflammatory Changes

  • Dermatomyositis

    Representative muscle biopsy micrograph (from another patient) shows inflammatory myopathic changes seen in dermatomyositis. (From Reference 3 , with permission.)[rc.rcjournal.com] Patients may have difficulty rising from a chair or squatting and then raising themselves from this position.[emedicine.medscape.com] Biopsy was suggestive of inflammatory muscle disease in 51 (75%) and normal or nonspecific in 14.8%.[ncbi.nlm.nih.gov]

  • Inclusion Body Myositis

    Muscle biopsy shows inflammatory reaction in association with degenerative changes of the muscle fibers.[scielo.br] The most common reasons for presentation are related to weakness of the quadriceps muscles, such as difficulty rising from low chairs or from the squatting or kneeling positions[ibmmyositis.com] We report a typical case of IBM, in which diagnosis was possible only after three muscle biopsies.[scielo.br]

  • Tropical Myositis

    Sixteen showed changes of suppurative myositis i.e. non-specific acute inflammatory reaction, muscle necrosis with myocytolysis, vacuolation of cytoplasm and loss of striations[ncbi.nlm.nih.gov] Twenty four muscle biopsies were taken.[ncbi.nlm.nih.gov]

    Missing: Difficulty Rising from a Squatting Position
  • Polymyositis

    Muscle biopsy shows chronic inflammatory changes consistent with polymyositis.[emedicine.com]

    Missing: Difficulty Rising from a Squatting Position
  • Pyomyositis

    Pyomyositis, also known as tropical pyomyositis or myositis tropicans, is a bacterial infection of the skeletal muscles which results in an abscess. Pyomyositis is most common in tropical areas but can also occur in temperate zones. Pus discharge culture and sensitivity X ray of the part to rule out osteomyelitis[…][en.wikipedia.org]

    Missing: Difficulty Rising from a Squatting Position
  • Childhood Dermatomyositis

    Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis. In JDM, the body's immune system attacks blood vessels throughout[…][en.wikipedia.org]

    Missing: Difficulty Rising from a Squatting Position
  • Intravenous Drug Abuse

    Intravenous drug abuse rates in the United States have increased exponentially in recent years. Ohio is one of 5 states with the highest age-adjusted drug overdose death rates, with drug overdose causing 39.1 of every 100,000 deaths. In patients who survive, the associated morbidity poses a significant public[…][ncbi.nlm.nih.gov]

    Missing: Difficulty Rising from a Squatting Position
  • Trichinellosis

    Abstract On January 15, 2017, a hospital physician notified the Alameda County Public Health Department (ACPHD) in California of a patient with a suspected diagnosis of trichinellosis, a roundworm disease transmitted by the consumption of raw or undercooked meat containing Trichinella spp. larvae (1). A family member[…][ncbi.nlm.nih.gov]

    Missing: Difficulty Rising from a Squatting Position
  • Neuromuscular Junction Disorder

    Biopsies of the cricopharyngeus muscle may show the inflammatory changes. 13 Previous retrospective series suggested that PM is the most common type of myositis, followed[nature.com] One maneuver that may demonstrate weakness is to have the patient squat down and rise to the standing position without any assistance from their arms.[ahcmedia.com] […] iii) Muscle Biopsy: there is necrosis of muscle fibers with an inflammatory infiltrate.[academic.sun.ac.za]

  • Inclusion Body Myopathy

    Muscle Pathology Muscle biopsy from patient III-1 showed myopathic and neuropathic changes with marked fiber size variation, scattered or clusters of small atrophic angulated[journals.plos.org] The most common reasons for presentation are related to weakness of the quadriceps muscles, such as difficulty rising from low chairs or from the squatting or kneeling positions[ibmmyositis.com] Muscle biopsy from patient II-13 showed combined neuropathic and myopathic changes, including marked fiber size variation, scattered or clusters of small atrophic angulated[journals.plos.org]

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