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18 Possible Causes for Difficulty Rising from a Squatting Position, Proximal Muscle Weakness of the Lower Extremity

  • Dermatomyositis

    Patients may have difficulty rising from a chair or squatting and then raising themselves from this position.[emedicine.medscape.com] Proximal muscle weakness (upper or lower extremity and trunk) 3. Elevated serum creatine kinase or aldolase level 4. Muscle pain on grasping or spontaneous pain 5.[aafp.org] […] of proximal and distal muscles of the upper and lower extremities and either finger flexor weakness, wrist flexor greater than wrist extensor weakness, or quadriceps weakness[doi.org]

  • Inclusion Body Myositis

    The most common reasons for presentation are related to weakness of the quadriceps muscles, such as difficulty rising from low chairs or from the squatting or kneeling positions[ibmmyositis.com] Inclusion body myositis features a slowly progressive inflammatory myopathy characterized by progressive proximal muscle weakness in the lower extremities, followed by proximal[ncbi.nlm.nih.gov] We present a case of a 76-year-old woman with systemic lupus erythematosus (SLE) who developed proximal muscle weakness of lower extremities and mild elevation of serum creatine[ncbi.nlm.nih.gov]

  • Hereditary Proximal Myopathy with Early Respiratory Failure

    They presented between the ages of 13 to 29 with proximal weakness in the lower extremities manifesting with difficulty on stairs or rising up from a squatting position (Table[bmcneurol.biomedcentral.com] […] early proximal weakness of the upper and lower extremities accompanied by respiratory muscle involvement, especially of the diaphragm.[medical-dictionary.thefreedictionary.com] Weakness may also involve the proximal muscles of the lower extremities, proximal and/or distal muscles of the upper extremities, and axial muscles.[ncbi.nlm.nih.gov]

  • Secondary Myopathy

    Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] On neurological examination, she had a proximal gradient of muscle weakness, moderate weakness of the upper extremities, 4 to 4 , and she was unable to flex her proximal lower[hopkinsarthritis.org] […] up from a squatted position, climbing stairs.[sites.google.com]

  • Distal Myopathy

    Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] Affected patients developed distal weakness in anterior foreleg muscles followed by progressive distal upper and proximal lower extremity involvement.[ncbi.nlm.nih.gov] […] tenderness • No joint tenderness or swelling • Significant proximal muscle weakness in both upper and lower extremities • No focal neurologic abnormalities Case 2: Question[studocu.com]

  • Distal Myopathy Type 3

    Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] Weakness affects predominantly proximal muscles in the upper limbs and later distal weakness in the lower extremities causing foot drop unresponsive to steroids.[neuroweb.us] Anterior compartment muscles of the distal lower extremities eventually become weak as well.[orpha.net]

  • Polyglucosan Body Myopathy Type 2

    Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] Weakness affects predominantly proximal muscles in the upper limbs and later distal weakness in the lower extremities causing foot drop unresponsive to steroids.[neuroweb.us] […] up from a squatted position, climbing stairs.[sites.google.com]

  • Myoadenylate Deaminase Deficiency

    Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] She had slight muscle weakness in her facial and upper extremities, and severe muscle weakness and atrophy in lower extremities more marked in the proximal portions.[ncbi.nlm.nih.gov] […] up from a squatted position, climbing stairs.[sites.google.com]

  • Inclusion Body Myopathy

    The most common reasons for presentation are related to weakness of the quadriceps muscles, such as difficulty rising from low chairs or from the squatting or kneeling positions[ibmmyositis.com] It typically presents with distal upper extremity weakness accompanied by proximal lower extremity muscle weakness.[patient.info] HIBM is an adult-onset, autosomal recessive disorder, characterized by slow progression of muscle weakness, both distal and proximal, but with the unusual feature of relative[genedx.com]

  • Congenital Myopathy with Excess of Thin Filaments

    Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] […] arm/distal leg (scapuloperoneal Pattern) weakness) Proximal arm/distal leg pattern of weakness affects the periscapular muscles of the proximal upper extremity and the anterior[sites.google.com] […] up from a squatted position, climbing stairs.[sites.google.com]

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