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27 Possible Causes for Difficulty Rising from Chair, Muscle Biopsy Abnormal, Weakness after Climbing Stairs

  • Duchenne Muscular Dystrophy

    Diagnosis of Duchenne Muscular Dystrophy A muscle biopsy (taking a sample of muscle) for dystrophin studies can be done to look for abnormal levels of dystrophin in the muscle[disabled-world.com] […] symptoms are noticed, such as weakness, clumsiness, a Gowers’ sign, difficulty with stair climbing, or toe walking.[ncbi.nlm.nih.gov] As the condition progresses, muscle weakness leads to functional difficulties (difficulty climbing stairs or rising from a chair).[orpha.net]

  • Polymyositis

    Muscle biopsy abnormalities at some time during their disease: i. degeneration and regeneration of muscle fibers ii. necrosis iii. phagocytosis iv. interstitial mononuclear[clinicaltrials.gov] & have to be careful on stairs & ladders (don't tell the Professors who are looking after me that I climb ladders) They know.I am very positive & determined not to let it[steadyhealth.com] Symptoms The gradual onset of weakness over weeks or months Difficulty rising from a low-seated chair or combing one’s hair Torso or “core” weakness Difficulty swallowing[hopkinsmyositis.org]

  • Becker Muscular Dystrophy

    Electromyography was abnormal in all patients. Muscle biopsy in 1 patient demonstrated normal immunostaining for dystrophin.[ncbi.nlm.nih.gov] As time goes by, there may be muscle weakness which causes difficulty with running, climbing stairs or walking long distances.[treat-nmd.eu] As the condition progresses, muscle weakness leads to functional difficulties (difficulty climbing stairs or rising from a chair).[orpha.net]

  • Muscular Dystrophy

    This condition is typically characterized by large and abnormally distributed mitochondria on muscle biopsy, which can distinguish this condition from the other muscle conditions[ncbi.nlm.nih.gov] Individuals develop a waddling gait and have difficulty when rising from chairs, climbing stairs, or carrying heavy objects. They fall frequently and are unable to run.[web.archive.org] Under the microscope, the muscle of a positive biopsy generally shows dead tissue and abnormally large muscle fibers.[cedars-sinai.edu]

  • Limb-Girdle Muscular Dystrophy

    Muscle biopsy abnormalities in two individuals very early in the course of their disease suggest that biopsy would probably be useful in detection of preclinical disease in[pediatrics.aappublications.org] Difficulties in rising from a chair or toilet seat and difficulties in climbing stairs are common.[encyclopedia.com] She began to experience proximal muscle weakness of both lower limbs without obvious inducement, which markedly increased when she climbed the stairs or stood up after squatting[ncbi.nlm.nih.gov]

  • Polymyalgia Rheumatica

    Microscopic and laboratory examination of muscle tissue samples (biopsy) from affected individuals does not usually reveal any muscle abnormality.[rarediseases.org] Patients may complain of difficulty rising from their chair, combing their hair, or fastening or unhooking a bra.[clinicaladvisor.com] The stiffness may be so bad that you may have difficulty turning over in bed, rising from a bed or a chair, or raising your arms above shoulder height (for example, to comb[patient.info]

  • Steroid Myopathy

    Muscle biopsy can also be performed. In the chronic presentation there is atrophy of type II muscle fibers without evidence of inflammation or necrosis.[robertbeckmd.com] Patients often have weakness and an inability to perform activities such as rising from chairs, climbing stairs, or bringing their arms over their heads.[livestrong.com] Three weeks after the patient's high-dose steroid was increased, she reported difficulty rising from a chair to the standing position.[jaoa.org]

  • Dermatomyositis

    Muscle biopsy abnormalities at some time during their disease: i. degeneration and regeneration of muscle fibers ii. necrosis iii. phagocytosis iv. interstitial mononuclear[clinicaltrials.gov] Typical complaints include difficulty rising from a low chair, walking up steps, and washing one’s hair.[accessmedicine.mhmedical.com] Running, climbing stairs, sitting from a lying position or standing from a seated position may become difficult.[arthritis.org]

  • Inclusion Body Myositis

    Muscle biopsy may display several common findings including; inflammatory cells invading muscle cells, vacuolar degeneration, inclusions or plaques of abnormal proteins.[phoenixstemcelltreatmentcenter.com] Our patient reported difficulties in standing from a seated position and in climbing stairs.[jmedicalcasereports.com] First signs are weakness or even atrophy of the quadriceps or of the finger flexors, leading to difficulties in rising from chairs or ground, walking stairs, gripping, lifting[orpha.net]

  • Amyotrophic Lateral Sclerosis

    Only about 10% of ALS patients have abnormal nerve conduction study results, but the test can also suggest other diagnoses. A muscle biopsy.[webmd.com] Patients typically have difficulty rising from a chair, climbing stairs, and walking. Increased temperatures from fever or the environment may worsen the weakness.[web.archive.org] The main symptom of LEMS is muscle weakness, therefore patients typically have difficulty rising from a chair, climbing stairs and walking.[web.archive.org]