Hereditary angioedema (HAE) type 3 stems from mutations in Hageman factor XII, unlike types 1 and 2, in which either deficiency or impaired function of C1 esterase inhibitor (C1-INH) is the principal cause of angioedema, profound abdominal pain, and erythema marginatum. The recurrent, unpredictable, and abrupt onset[…]
[symptoma.com]