Create issue ticket

3,505 Possible Causes for Difficulty Walking, EMG Shows Evidence of Reinnervation, Muscle Biopsy Abnormal

  • Motor Neuron Disease

    For patients with MND affecting the LMNs, the EMG will show evidence of: (1) acute denervation, which is ongoing as motor neurons degenerate, and (2) chronic denervation and[en.wikipedia.org] The results of electromyography and muscle biopsy were compatible with ALS. However, supranuclear vertical gaze palsy and slow saccades are seen.[ncbi.nlm.nih.gov] In addition to changes in behavior, personality and language skills that characterize FTD, people with ALS and FTD also have difficulty walking, standing, using their hands[theaftd.org]

  • Muscular Dystrophy

    This condition is typically characterized by large and abnormally distributed mitochondria on muscle biopsy, which can distinguish this condition from the other muscle conditions[ncbi.nlm.nih.gov] […] is usually unable to walk Frequent falls Difficulty getting up from the floor and climbing stairs Difficulty with running, hopping, and jumping Loss of muscle mass Toe walking[medlineplus.gov] Under the microscope, the muscle of a positive biopsy generally shows dead tissue and abnormally large muscle fibers.[cedars-sinai.edu]

    Missing: EMG Shows Evidence of Reinnervation
  • Becker Muscular Dystrophy

    Electromyography was abnormal in all patients. Muscle biopsy in 1 patient demonstrated normal immunostaining for dystrophin.[ncbi.nlm.nih.gov] […] is usually unable to walk Frequent falls Difficulty getting up from the floor and climbing stairs Difficulty with running, hopping, and jumping Loss of muscle mass Toe walking[nlm.nih.gov] Elevated serum CK Skeletal muscle biopsy showing decreased dystrophin quantity Panel overlap The gene on this panel is also included on our Autism Intellectual Disability[unmc.edu]

    Missing: EMG Shows Evidence of Reinnervation
  • Spinal Muscular Atrophy

    Muscle biopsies showed typical signs of neurogenic damage. Molecular genetic analysis showed mutations of the ASAH1 gene.[ncbi.nlm.nih.gov] Children can walk independently but may have difficulty walking or running, rising from a chair, or climbing stairs.[ninds.nih.gov] The muscle biopsy showing atrophic fibers of both types, hypertrophic fibers of one type (usually type I), and in chronic cases type grouping.[doi.org]

    Missing: EMG Shows Evidence of Reinnervation
  • Adult Spinal Muscular Atrophy

    Muscle biopsy- reveals evidence of devervation with no other structural abnormalities.[en.wikibooks.org] The mobility component is paid to people who have difficulty walking and in using public transport; the personal care component is paid to those who need help with such tasks[daneverard.co.uk] In some situations other tests such as an EMG electromyography (EMG) or muscle biopsy may be needed because it is not possible to conduct the SMN gene tests or no abnormality[genome.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Glycogen Storage Disease Type 2

    Autophagy in Pompe mouse models The morphological evidence for abnormal autophagy in muscle biopsies from adult Pompe patients was first reported by Andrew Engel in 1970 ([ncbi.nlm.nih.gov] Affected individuals often suffer from limb-girdle syndrome and claim walking difficulties.[symptoma.com] […] running 30 (32%) • Difficulty performing sports 22 (23%) • Difficulty climbing stairs 24 (26%) • Difficulty walking 15 (16%) • Difficulty rising from an armchair 11 (12%)[ojrd.com]

    Missing: EMG Shows Evidence of Reinnervation
  • Spinal Muscular Atrophy Type 3

    […] is being broken down); distinctive abnormalities on muscle biopsy; characteristic electromyographic and nerve conduction abnormalities; and genetic testing.[healthofchildren.com] Type 4 begins in young adulthood and comes with difficulty walking, or the possibility of eventually being confined to a wheelchair.[sandiegouniontribune.com] In some cases, when the SMN gene test is not possible or does not show any abnormality, other tests such as an EMG electromyography (EMG) or muscle biopsy may be indicated[psychology.wikia.com]

    Missing: EMG Shows Evidence of Reinnervation
  • Duchenne Muscular Dystrophy

    Diagnosis of Duchenne Muscular Dystrophy A muscle biopsy (taking a sample of muscle) for dystrophin studies can be done to look for abnormal levels of dystrophin in the muscle[disabled-world.com] DMD symptoms may include: difficulty walking a loss of ability to walk enlarged calves learning disabilities, which occurs in about one-third of affected individuals a lack[healthline.com] […] fibers) For Duchenne and Becker muscular dystrophies, muscle biopsy may show whether dystrophin, a muscle protein, is missing or abnormal, and DNA testing is used to analyze[webmd.com]

    Missing: EMG Shows Evidence of Reinnervation
  • Limb-Girdle Muscular Dystrophy

    Muscle biopsy abnormalities in two individuals very early in the course of their disease suggest that biopsy would probably be useful in detection of preclinical disease in[pediatrics.aappublications.org] This means that people may have frequent falls, and may have difficulty walking longer distances, climbing stairs and getting up from the floor.[musculardystrophyuk.org] Some LGMD subtypes have distinguishing features, including pattern of muscle involvement, cardiac abnormalities, extramuscular involvement, and muscle biopsy findings.[ncbi.nlm.nih.gov]

    Missing: EMG Shows Evidence of Reinnervation
  • Stiff-Person Syndrome

    Previous diagnostic testing, including magnetic resonance imaging, muscle biopsy, and electromyography, showed no specific abnormalities and blood was negative for anti-GAD[redorbit.com] Many who suffer from SPS also have abnormal posture, with a hunched and stiff stance, and difficulty walking.[disability-benefits-help.org] walking Difficulty in walking 0002355 Emotional lability Emotional instability 0000712 Exaggerated startle response 0002267 Paraspinal muscle hypertrophy 0012894 Rigidity[rarediseases.info.nih.gov]

    Missing: EMG Shows Evidence of Reinnervation

Similar symptoms