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11 Possible Causes for Difficulty Walking, Myoclonic Jerking, Onset of Disease between 25 and 40 Years of Age

  • Wilson Disease

    jerking similar to that seen in progressive myoclonic syndrome.[web.archive.org] Onset is slow and begins between 11 and 25 years of age. Signs and Symptoms In about 40 to 50% of patients, the disease first affects the central nervous system (CNS).[diagnose-me.com] Signs and symptoms of these problems can include clumsiness, tremors, difficulty walking, speech problems, impaired thinking ability, depression, anxiety, and mood swings.[ghr.nlm.nih.gov]

  • Acute Cerebellar Ataxia

    Four weeks later he developed myoclonic jerks. Electroencephalogram showed characteristic periodic complexes time-locked with myoclonus.[ncbi.nlm.nih.gov] The age of onset may vary between 40 - 80 years and the mean duration of ataxia between 3 - 25 years.[neuroweb.us] walking Speech disturbances with slurred speech and changes in tone, pitch, and volume Visual complaints Abnormal eye movements Headache Nausea and vomiting Lightheadedness[cookchildrens.org]

  • Alcoholic Cerebellar Degeneration

    The age of onset may vary between 40 - 80 years and the mean duration of ataxia between 3 - 25 years.[neuroweb.us] Symptoms may include: problems with learning and memory, including amnesia forgetfulness poor coordination difficulty walking Alcoholic neuropathy This condition occurs when[healthline.com] These patients will have difficulty when walking in tandem.[mdedge.com]

  • Subacute Cerebellar Degeneration

    Other clinical signs include early falling and fine myoclonic jerks of the fingers /limb and can be elicited by tapping the limb.[neuroweb.us] walking.[rarediseases.info.nih.gov] […] as faced during first attack that is difficulty in walking with imbalance and scanning dysarthria.[pubs.sciepub.com]

  • Adult-Onset Autosomal Recessive Cerebellar Ataxia

    […] to manage her frequent myoclonic jerking.[jnnp.bmj.com] The age of onset may vary between 40 - 80 years and the mean duration of ataxia between 3 - 25 years.[neuroweb.us] The first indication generally is difficulty walking (gait ataxia). The condition typically progresses to the arms and trunk.[mayoclinic.org]

  • Cerebellar Ataxia with Peripheral Neuropathy Type 2

    Other clinical signs include early falling and fine myoclonic jerks of the fingers /limb and can be elicited by tapping the limb.[neuroweb.us] The first indication generally is difficulty walking (gait ataxia). The condition typically progresses to the arms and trunk.[mayoclinic.org] Signs and symptoms of AT can include: difficulty walking – most children need to use a wheelchair by 10 years of age increasingly slurred, slow and unclear speech (dysarthria[nhs.uk]

  • Early-Onset Cerebellar Ataxia

    The age of onset may vary between 40 - 80 years and the mean duration of ataxia between 3 - 25 years.[neuroweb.us] Signs and symptoms of AT can include: difficulty walking – most children need to use a wheelchair by 10 years of age increasingly slurred, slow and unclear speech (dysarthria[nhs.uk] walking, gait abnormalities, tremors, and heart problems.[ataxia.org]

  • Early-Onset Spastic Ataxia - Neuropathy Syndrome

    Other clinical signs include early falling and fine myoclonic jerks of the fingers /limb and can be elicited by tapping the limb.[neuroweb.us] Signs and symptoms of AT can include: difficulty walking – most children need to use a wheelchair by 10 years of age increasingly slurred, slow and unclear speech (dysarthria[nhs.uk] He also gives history consistent with wash basin symptom and progressively increasing difficulty walking in darkness since 12 years.[jmgims.co.in]

  • Spinocerebellar Ataxia with Rigidity and Peripheral Neuropathy

    Other clinical signs include early falling and fine myoclonic jerks of the fingers /limb and can be elicited by tapping the limb.[neuroweb.us] ) Difficulty with writing and eating Slow eye movements The symptoms of ataxia may look like other conditions or medical problems.[hopkinsmedicine.org] Subacute necrotizing encephalopathy, also called Leigh disease, is a lethal disorder of infancy marked by psychomotor delay, myoclonic jerks, paralyses of eye movements, and[britannica.com]

  • Cognitive Impairment with or without Cerebellar Ataxia

    Other clinical signs include early falling and fine myoclonic jerks of the fingers /limb and can be elicited by tapping the limb.[neuroweb.us] walk.[bcm.edu] Gait/posture abnormalities - Difficulty maintaining normal upright posture, balance, coordinated walking, and running.[hopkinsmedicine.org]

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