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32 Possible Causes for Diffuse Bone Demineralization

  • Osteoporosis

    The study aims to investigate the association between nonalcoholic fatty liver disease (NAFLD) and osteoporosis.We employed a retrospective cohort study design using the National Health Insurance Research Database in Taiwan. Our study included 2 cohorts: 4318 patients with NAFLD and 17,272 patients without NAFLD[…][ncbi.nlm.nih.gov]

  • Neonatal Severe Primary Hyperparathyroidism

    A skeletal survey demonstrated multiple rib fractures, diffuse bone demineralization, and chondrodystrophy in the distal humeri and femora. Figure 1.[academic.oup.com] He was found to have multiple fractures and diffuse bone demineralization, with a marked elevation in serum ionized calcium (1.99 mmol/L) and elevated serum levels of intact[academic.oup.com] Radiographs of the patient demonstrating diffuse demineralization (A), multiple rib fractures (arrows), and chondrodystrophy of the distal humerus (B) and femur (C).[academic.oup.com]

  • Reflex Sympathetic Dystrophy

    Severe diffuse demineralization was noted on radiographs and diffuse hyperactivity on bone scans starting at the early vascular phase.[ncbi.nlm.nih.gov]

  • Oncogenic Osteomalacia

    Sequences of comparative radiographs taken 1 year apart (January 2008 and February 2009) demonstrate progressive diffuse bone demineralization, widening of the growth plates[pediatrics.aappublications.org] Site Enter text Size Enter text Tumor effect on bone The hypophosphatemia and low 1,24 (OH) Vit D cause diffuse skeletal demineralization and possibly insufficiency fractures[orthopaedicsone.com]

  • Mucolipidosis

    These infants showed severe skeletal changes with diffuse periosteal new bone formation in long bones and ribs, marked osteopenia, and resorption of scapula, clavicula, and[ncbi.nlm.nih.gov] There was also irregular demineralization of metaphyses of long tubular bones, as seen in rickets.[ncbi.nlm.nih.gov]

  • Warburg Micro Syndrome 3

    Radiological examination of the skeleton showed a left curved scoliosis, convex vertebral bodies, diffuse osseous demineralization, thin diaphyses of the long bones, bilateral[cags.org.ae]

  • Renal Tubular Dysfunction

    The three patients with proximal renal tubular dysfunction had delayed bone development and diffuse demineralization but no definite evidence of rickets.[nejm.org]

  • Epidermal Nevus Syndrome

    Radiographs of the legs showed enlarged and dystrophic bones, diffuse demineralization and soft tissue calcifications in the right thigh.[nature.com]

  • Hypophosphatasia

    Presence of thickened, wavy bones due to repetitive callus formation in fragile, fracture-susceptible bones with diffuse demineralization in the former and macrocrania, reduced[e-ultrasonography.org] Improvements in skeletal quality included diffusely increased mineral content, corrected or improved endochondral and membranous bone formation, fracture mending, reduced[nejm.org] […] skeletal deterioration was observed, except in Patient 4, whose consent for treatment was withdrawn during the intravenous infusion and who subsequently had marked skeletal demineralization[nejm.org]

  • Primary Basilar Impression

    […] focal “punched-out” lesions Paget disease ( p. 967 ) Diffuse demineralization that may accompany the more classic presentation of large osteolytic areas of bone destruction[radiologykey.com] Diffuse Demineralization SK5. Enlargement or Destruction of the Sella Turcica SK6. Increased Radiodensity of the Calvarium SK7. Intracranial Calcifications SK8.[radiologykey.com] […] prostate origins are common in adults; in children, neuroblastoma and leukemia are more likely Multiple myeloma ( p. 834 ) Characterized by diffuse demineralization with[radiologykey.com]

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