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26 Possible Causes for Diffuse Hepatic Steatosis, Hypoglycemia, Splenomegaly

  • Liver Cirrhosis

    Cardinal symptoms include fasting hypoglycemia, lactic acidosis and hepatomegaly as well as neutropenia.[] We performed LS in 83 patients with massive splenomegaly ( 30 cm) secondary to portal hypertension and liver cirrhosis.[] First, perfusion, iron overload, hepatic steatosis, liver inflammation and edema can confound the interpretation of diffusion parameters. 54 Second, DWI is sensitive to motion-related[]

  • Hepatitis

    Dehydration with drying of mucous membranes Telangiectasis (spider angiomata) and esophageal varices Jaundice Ascites Utricarial rashes Portal Hypertension Hepatomegaly and Splenomegaly[] diffusely decreased parenchymal attenuation on noncontrast CT diffuse edematous change hepatic steatosis may be a cause (steatohepatitis) or a result of acute hepatitis possible[] Despite advances in intensive care management, mortality continues to be high (40–80%) and is partly related to ALF's complications, such as cerebral edema, sepsis, hypoglycemia[]

  • Fatty Liver

    , Spain. Abstract Here we report a 7-month-old girl with long-chain 3-hydroxyacyl-coenzyme A dehydrogenase (LCHAD) deficiency with hypoketotic hypoglycemia[] These may initially include jaundice or a yellowish tinge to the skin and eyes, muscle wasting, hair thinning, abnormal skin blood vessels called spider angiomata, and splenomegaly[] hepatic steatosis Wilson disease hepatic fatty infiltration diffuse hepatic steatosis focal hepatic steatosis Promoted articles (advertising)[]

  • Reye Syndrome

    In Reye-like syndrome, because of inborn errors of metabolism, hypoglycemia, hypoketonemia, elevated ammonia, and organic aciduria are often evident.[] Hepatomegaly is sometimes present, but splenomegaly is absent.[] Abstract Analysis of the liver histopathology in 19 children with clinical Reye syndrome (RS) revealed that nine had diffuse panlobular steatosis, one giant cell hepatitis[]

  • Hepatosplenic Amyloidosis

    FACTITIOUS C0271703 HYPOGLYCEMIA REACTIVE C0271710 Aldosteronism Secondary C0271728 PITUITARY HYPOTHYROIDISM C0271789 ANEMIA OF DECREASED VITAMIN B12 ABSORPTION C0271952[] Hypersplenism is defined as one or more blood cytopenias in the setting of splenomegaly.[] Abnormal retention of lipids within hepatocytes Cholangitis Inflammation of bile ducts Reactive hepatitis Aspecific and mild inflammatory cell infiltrate of portal spaces[]

  • Toxic Hepatitis

    Autoimmune hepatitis manifests insidiously as fatigue, anorexia, weight loss, jaundice, ascites, portal hypertension, hepatomegaly, and splenomegaly.[] diffusely decreased parenchymal attenuation on noncontrast CT diffuse edematous change hepatic steatosis may be a cause (steatohepatitis) or a result of acute hepatitis possible[] Findings include: hepatomegaly 15.5 cm at the midclavicular line 4 possible decreased attenuation around the portal system and at the hepatic hilum (periportal edema) possible[]

  • Macronodular Cirrhosis

    Continued fluid and electrolyte imbalances and inefficient metabolism of nutrients produce ascites, hypoglycemia, and hypoproteinemia.[] There is splenomegaly and enlargement of collateral vessels beneath the anterior abdominal wall (arrows) as a result of portal hypertension.[] On CT, an objective measurement using Hounsfield units of 48 on a noncontrast study is most accurate in diagnosing hepatic steatosis.[]

  • Chronic Liver Disease

    Nocturnal hypoglycemia was seen in 22% of patients.[] About a quarter, i.e. 26.94% of the cases, had no complications; 17.62% only had ascites and 16.06% presented with IHV obliteration, and ascites with splenomegaly.[] Cutoff values for grading steatosis varied across studies included in the meta-analysis but were not less than 25 % for moderate to severe hepatic steatosis.[]

  • Citrullinemia Type 2

    Hypoglycemia and hypergalactosemia have also been reported as possible features of neonatal-onset CTLN2.[] No splenomegaly was seen. At gross examination at operation, the livers in all seven patients showed moderate to marked enlargement and looked yellowish and waxy.[] Some previous studies [19,35,36] indicated that NICCD patients’ liver biopsies showed varying degrees of hepatic steatosis, diffuse hepatocyte microbubble degeneration, or[]

  • Mauriac's Syndrome

    The records revealed fluctuating and poorly controlled sugar levels, especially with multiple episodes of hypoglycemia.[] Hepatomegaly was universal with splenomegaly in 16%.[] Liver biopsy was performed, which revealed findings consistent with diffuse hepatocellular glycogen accumulation. There was no steatosis, fibrosis or inflammation.[]

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