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28 Possible Causes for Diplopia, Prominent Sulci

  • Leptomeningeal Metastasis

    Nine months after the allogeneic SCT, she presented with oculomotor and trochlear nerve palsy (diplopia, ptosis of the right upper eye lid, and dilated right pupil).[] The lesions were more prominent in the cerebellar sulci compared with in the cerebral sulci.[] For instance, a single patient may present with diplopia and urinary incontinence. Stroke-like episodes have also been described in LM patients.[]

  • Hypertensive Encephalopathy

    Other symptoms may include increased irritability, vomiting, diplopia, seizures, twitching and myoclonus of the limbs.[] There was complete resolution of cerebral edema in all patients and mild interval prominence of the cerebral sulci, which can indicate cerebral volume loss, in three out of[]

  • Glioblastoma Multiforme

    Case 2: Meningeal involvement A 31-year-old man presented with seizures and subsequent diplopia.[] (a) On an axial nonenhanced CT scan, the sulci in the right hemisphere are normally prominent; on the left, the parietal sulci are effaced within a wedge-shaped region of[] […] o Headache, especially retroorbital; sometimes worse upon awakening, improves during the day o Vomiting (with or without nausea) o Visual changes (blurring, blind spots, diplopia[]

  • Obstructive Hydrocephalus

    A 46-year-old man developed intermittent headache, diplopia, and visual obscuration for two months. Funduscopic examination showed optic disk swelling in both eyes.[] Pre-contrast axial CT Sulci and gyri are very prominent due to cortical atrophy, unlike in obstructive hydrocephalus where there is effacement of sulci and gyri.[] A 76-year-old female presented with a large upper basilar artery (BA) aneurysm causing obstructive hydrocephalus after coil embolization manifesting as diplopia.[]

  • Creutzfeldt Jakob Disease

    Creutzfeldt-Jakob disease presenting with visual blurring, diplopia and visual loss: Heidenhain's variant. Ann Acad Med Singapore 1998; 27:854 –856 [Google Scholar] 11.[] B, Corresponding FLAIR image shows marked prominence of ventricles and sulci for the patient’s age.[]

  • Subacute Sclerosing Panencephalitis

    There was no history of redness, lacrimation, diplopia, headache, vomiting, seizures, and motor weakness.[] They can range from hyperintensities in the parietal and occipital region, brain stem lesions, and marked atrophy, causing prominence of sulci.[] There was no history of loss of consciousness, headache, vomiting, diplopia or any motor deficits. On examination, his vitals were stable.[]

  • Meningovascular Syphilis

    Holland et al reported the CT scan findings in 3 patients with meningovascular syphilis. [2] Less prominence of the cortical sulci in our first case suggested cortical atrophy[]

  • Primary Amebic Meningoencephalitis

    CT head showed prominent sulci suggestive of cerebral atrophy.[]

  • West Nile Encephalitis

    Arrows indicate subtle enhancement in the sulci. B and C, FLAIR images show increased signal intensity in the sulci, more prominent on the left than on the right.[]

  • Ondine Syndrome

    A final symptom which occurs in occasional patients with multiple system atrophy is diplopia, not unlike that seen in multiple sclerosis.[] The ventricles and sulci were thought to be slightly prominent for the patient's age. MRI findings are shown in Figure 1.[]

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