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68 Possible Causes for Direct Bilirubin Increased, Leukopenia, Lymphocytes Increased, Swinging Fever

  • Disseminated Tuberculosis

    Blood workup should include a complete cell blood count, that may show either leukopenia or leukocytosis, pancytopenia, agranulocytosis, aplastic anemia, leukoerythroblastic[symptoma.com] Monitoring for RFB toxicity (arthralgias, uveitis, leukopenia) is necessary.[path.upmc.edu] Complete blood count Leukopenia/leukocytosis may be present in miliary tuberculosis.[emedicine.medscape.com] Analysis may reveal increased leukocyte and lymphocyte counts, elevated protein and low glucose levels.[symptoma.com]

  • Toxoplasmosis

    Atypical lymphocytosis, mild anemia, leukopenia, and slightly elevated liver enzymes are common. The syndrome may persist for weeks but is almost always self-limited.[merck.com] Infant had hepatomegaly (liver edge 3 cm below right costal margin [RCM]), mild IUGR, CBC had 7% atypical lymphocytes, and there was a slight increase in SGOT(66).[ncbi.nlm.nih.gov]

    Missing: Swinging Fever
  • Viral Hepatitis

    Fever, nausea, vomiting, abdominal pain, leukopenia, thrombocytopenia, coagulopathy, and a marked rise in serum transaminase levels are invariably present.[ncbi.nlm.nih.gov] The risk for intermittent reactivation is increased with immunosuppression.[doi.org] […] autopsy due to nonspecific clinical features Better survival in children than adults ( J Hepatol 2011;55:1222 ) Laboratory Sudden, marked elevation of ALT or AST, fever, leukopenia[pathologyoutlines.com] Circulating lymphocytes, monocytes, and polymorphonuclear leukocytes may serve as the predominant site of viral latency.[doi.org]

    Missing: Swinging Fever
  • Typhus

    Some of the common abnormalities noted include proteinuria, leukopenia, thrombocytopenia, higher levels of transaminase, and hypoalbuminemia.[symptoma.com] Non-specific laboratory test results include increased transaminase levels, thrombocytopenia, leucopenia and CD4/CD8 lymphocyte ratio inversion.[orpha.net] Ehrlichiosis and anaplasmosis should be suspected in febrile patients with leukopenia and thrombocytopenia and mild to moderately elevated levels of hepatic transaminases.[wwwnc.cdc.gov] His investigations revealed lymphocytic leukocytosis, high erythrocyte sedimentation rate and immunofluorescence assay-IgM and IgG against Orientia tsutsugamushi Karp antigen[ncbi.nlm.nih.gov]

    Missing: Swinging Fever
  • Yellow Fever

    There is a safe and highly effective live-attenuated vaccine available to prevent yellow fever.[ncbi.nlm.nih.gov] These include: Complete blood count: The findings in a complete blood count for patients with yellow fever include leukopenia, thrombocytopenia, increased hemoglobin and hematocrit[symptoma.com] ( /-) CD56( /-)/CD3( ) ratio), activated T cells (CD4( ) and CD8( ) cells), and B lymphocytes.[ncbi.nlm.nih.gov] High fevers associated with bradycardia, leukopenia, and transaminase elevations may provide a clue to the diagnosis, and patients will be viremic during this period.[nejm.org]

  • Chronic Malaria

    The fever is referred to as a ‘swinging fever’ and the duration between fevers may point to a certain type of malaria: P. ovale/P. vivax 38-42 hours between fevers (‘tertian[southsudanmedicaljournal.com] lymphocytes in 3 (9%) and normal plasma cells in 11(38%) cases.[jpma.org.pk] In all types of malaria, the total white blood cell count is usually normal, but the numbers of lymphocytes and monocytes, two specific types of white blood cells, increase[health24.com] […] suffering from falciparum malaria in Ndolla (Zambia) and reported erythroid hyperplasia in 26(76%), myeloid hyperplasia in 25 (74%), excess eosinophil precursors in 3 (9%), increased[jpma.org.pk]

  • Liver Failure

    […] enzyme levels Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels elevated, usually 300 U/L; AST/ALT ratio 2:1 Hematologic Anemia Leukocytosis or leukopenia[clevelandclinicmeded.com] These findings translated to tests of upscaled adsorbents in a dynamic model for liver failure: upscaled Hepalbin adsorbent removes bile acids, direct bilirubin and indirect[ncbi.nlm.nih.gov] – measures all of the bilirubin in the blood; levels are increased with many liver diseases Direct bilirubin – measures a form of bilirubin that is conjugated (combined with[labtestsonline.org] […] bilirubin significantly better than MARS adsorbents and significantly increases ABiC.[ncbi.nlm.nih.gov]

    Missing: Swinging Fever
  • Hepatitis B

    Peripheral blood counts may show mild leukopenia, with or without relative lymphocytosis.[clevelandclinicmeded.com] Moreover, the frequencies of mutations (L173P, Q181R and A184V) in cytotoxic T lymphocyte epitopes increased before entecavir treatment.[ncbi.nlm.nih.gov] However, the ubiquitous expression of CD52 on lymphocytes and monocytes is predictive of the increased neutropenia, lymphopenia and infectious complications observed with[doi.org]

    Missing: Swinging Fever
  • Adult-Onset Still Disease

    In hospital it was found that she had swollen joints, a high swinging fever and blood tests that were consistent with severe inflammation.[nras.org.uk] AOSD patients with RHS showed higher frequencies of leukopenia, anemia, thrombocytopenia, hypoalbuminemia, hypofibrinogenemia, hypertriglyceridemia, hyperferritinemia, and[ncbi.nlm.nih.gov] Liver function tests revealed serum total bilirubin 0.8 mg/dL, serum direct bilirubin 0.45 mg/dL, SGPT/ALT 31.5 IU/L.[ijnm.in] Der‐Yuan Chen, Tsu‐Yi Hsieh, Chia‐Wei Hsieh, Fang‐Ju Lin and Joung‐Liang Lan, Increased apoptosis of peripheral blood lymphocytes and its association with interleukin‐18 in[doi.org]

  • Rickettsialpox

    Rocky Mountain spotted fever in Palestine. Harefuah 36 : 99 . 346. Vandamme, P., B. Pot, M. Gillis, P. Devos, K. Kersters, and J. Swings. 1996 .[dx.doi.org] Although laboratory tests are not diagnostic, a complete blood count with differential count may reveal leukopenia with relative lymphocytosis, and thrombocytopenia while[symptoma.com] Rocky Mountain spotted fever in Palestine. Harefuah 36 : 99. 346. Vandamme, P., B. Pot, M. Gillis, P. Devos, K. Kersters, and J. Swings. 1996.[doi.org] General Laboratory Findings Mildly elevated hepatic transaminases Mild leukopenia Mild thrombocytopenia, less common CONFIRMATION OF THE DIAGNOSIS IS BASED ON LABORATORY TESTING[cdc.gov]

    Missing: Direct Bilirubin Increased

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