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20 Possible Causes for Direct Bilirubin Increased, Physiological Neonatal Jaundice, Yellow Discoloration of the Skin

  • Neonatal Jaundice

    Jaundice, Physiological NeonatalNeonatal Jaundice, Physiological — Severe Jaundice in Newborn — Severe Jaundice in Neonate — Icterus Gravis Neonatorum[mesh.kib.ki.se] , and bronzed-baby syndrome (if high levels of direct bilirubin are present).[sharinginhealth.ca] Definition Neonatal jaundice is the yellowing discoloration of the skin and sclera of a neonate, which is caused by increased levels of bilirubin in the blood.[bestpractice.bmj.com]

  • Physiological Neonatal Jaundice

    Published on Jul 10, 2016 Physiological Neonatal Jaundice and Its causes. Physiological Neonatal Jaundice 1. PHYSIOLOGICAL NEONATAL JAUNDICE 10/07/2016 1 2.[slideshare.net] Definition (MSH) Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA.[fpnotebook.com] , and bronzed-baby syndrome (if high levels of direct bilirubin are present).[sharinginhealth.ca]

  • Neonatal Hepatitis

    Infants with this condition are usually jaundiced. Jaundice that is caused by neonatal hepatitis is not the same as physiologic neonatal jaundice.[en.wikipedia.org] The common symptoms include jaundice (yellow discoloration of the skin and the whites of the eyes) and hepatomegaly (liver enlargement).[biology-online.org] However, bilirubin again increased to 13.2 mg/dl at 5 months of age in spite of HSV IgG.[mjdrdypu.org]

  • Extrahepatic Cholestasis

    Whereas physiologic jaundice constitutes a common finding in neonates, a few cases present with cholestatic jaundice owing to various pathologic conditions, including extrahepatic[ncbi.nlm.nih.gov] discoloration of the skin (jaundice), dark urine, and pale stools.[medical-dictionary.thefreedictionary.com] An increase in urinary bilirubin is nearly always indicative of a corresponding increase in the serum direct fraction attributable to intrahepatic or extrahepatic cholestasis[medical-dictionary.thefreedictionary.com]

  • Rotor Syndrome

    Neonatal jaundice and Breast-milk jaundice Conjugated hyperbilirubinaemia Hepatocellular – Diminished hepatocyte function.[lifeinthefastlane.com] Introduction Jaundice refers to yellow discoloration of the skin, sclera, mucous membranes, and body fluids.[pedsinreview.aappublications.org] This is similar to Dubin-Johnson syndrome and both leads to increase conjugated (direct) bilirubin.[labpedia.net]

  • Jaundice

    This is called “physiologic” or normal neonatal jaundice. Most infants have this pattern so no testing is needed.[patients.gi.org] Jaundice is a yellow discoloration of the skin and mucous membranes caused by an excess accumulation of bilirubin in the blood.[medcomic.com] Nevertheless, serum direct bilirubin increased further up to 15 mg/dL.[ncbi.nlm.nih.gov]

  • Biliary Atresia

    Issues that should raise your concern: Prolonged neonatal jaundice Physiologic jaundice in healthy, full-term newborns typically resolves by the 5th or 6th day.[pedemmorsels.com] discoloration of the skin and whites of the eyes due to an abnormally high level of bilirubin (bile pigment) in the bloodstream, which is then excreted through the kidneys[beaumont.org] We evaluated the clinical impact and cost of reflex testing in infants with increased direct bilirubin ( 1.5 mg/dL; 25 μmol/L).[ncbi.nlm.nih.gov]

  • Crigler-Najjar Syndrome Type 1

    Physiological neonatal jaundice may peak at 85–170 µmol/l and decline to normal adult concentrations within two weeks. Prematurity results in higher levels.[en.wikipedia.org] This leads to jaundice, i.e. yellow discoloration of skin and eyes. Excess bilirubin can also damage the brain, muscles, and nerves.[medindia.net] The jaundice worsened following appendectomy, and the direct-reacting bilirubin increased, probably due to the ceftizoxime administered postoperatively.[ncbi.nlm.nih.gov]

  • Liver Cirrhosis

    […] history of alcohol excess, neonatal jaundice, hypertension, or hypercholesterolemia.[atsjournals.org] Yellow discoloration in the skin and eyes (jaundice) Fluid accumulation in your abdomen (ascites) Spiderlike blood vessels on your skin Redness in the palms of the hands[mayoclinic.org] – measures all of the bilirubin in the blood; levels are increased with many liver diseases Direct bilirubin – measures a form of bilirubin that is conjugated (combined with[labtestsonline.org]

  • Transient Familial Neonatal Hyperbilirubinemia

    Preferred Name Fetal and neonatal jaundice, NOS Synonyms Physiologic jaundice in newborn, NOS ID altLabel Physiologic jaundice in newborn, NOS Neonatal jaundice, NOS Foetal[purl.bioontology.org] Jaundice is a yellow discoloration of the skin and eyes caused by hyperbilirubinemia (elevated serum bilirubin concentration).[merckmanuals.com] It is reported to have a 0.09 unit increase on Bilirubin levels (Direct bilirubin). No specific risk allele was identified in the study.[selfdecode.com]