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34 Possible Causes for Discoloration of the Lower Extremity, Gangrene, Pruritus

  • Raynaud's Disease

    […] of the toes Gangrene of the fingertips Extreme constriction of blood vessels (peripheral) Tissue hypoxia Skin, muscle, and tissue atrophy Ulceration Ischemic gangrene Raynaud[disability-benefits-help.org] An examination revealed venous changes, chronic ulceration, and digit discoloration in upper and lower extremities.[ncbi.nlm.nih.gov] These sores may progress to gangrene. In rare cases, gangrene may lead to finger amputation.[hopkinsmedicine.org]

  • Thrombosis

    Examinations after death have shown that thrombosis exists for some distance around the gangrenous mass.[thesaurus.com] Patients with venous thrombosis may have variable discoloration of the lower extremity.[emedicine.medscape.com] […] polyhydramnios 657 postmaturity prediabetes 648.8 pre-eclampsia (mild) 642.4 premature rupture of membranes 658.1 previous prolapse, uterus 654.4 proteinuria (gestational) 646.2 pruritus[icd9data.com]

  • Erythromelalgia

    It is possible to get ulceration, necrosis and gangrene as complications of erythromelalgia.[dermnetnz.org] […] of the lower extremities ( Figure 3 ).[dovepress.com] A 15-year-old girl diagnosed with erythromelalgia was admitted to the hospital with severe pain in her feet associated with burning, pruritus, erythema, and swelling.[ncbi.nlm.nih.gov]

  • Calcinosis Cutis

    In very rare cases, Calcinosis Cutis can cause gangrene due to blockage of blood flow.[epainassist.com] They tend to be distributed bilaterally and symmetrically, and they are most commonly located on the lower extremities, which may relate to poor circulation, as well as the[cjasn.asnjournals.org] […] erythrokeratodermas and related disorders Keratodermas Kro Dariers disease and HaileyHailey disease Daniel Hohl Theodora Mauro and leanPhilippe Gorog Mosaicism and linear lesions Pruritus[books.google.it]

  • Deep Vein Thrombosis

    The patient will present with a swollen, cyanotic, painful leg that may or may not show signs of venous gangrene.[ncbi.nlm.nih.gov] […] chronic debilitating condition seen in about 43% of patients with DVT within two years Patients present with a painful heavy leg and may also have cramps, paraesthesia, and pruritus[dx.doi.org] Patients with venous thrombosis may have variable discoloration of the lower extremity.[emedicine.medscape.com]

  • Calciphylaxis

    Acral dry gangrene was observed.[ncbi.nlm.nih.gov] In addition, he had violaceous discoloration in a livedo reticularis pattern over his lower extremities bilaterally.[jamanetwork.com] A significant improvement of skin condition and pruritus resulted.[karger.com]

  • Idiopathic Scrotal Edema

    Okizuka H, Sugimura K, Yoshizako T (1992) Fournier’s gangrene: diagnosis based on MR findings.[link.springer.com] extremities, with brownish discoloration, discomfort but not marked pain, and sometimes skin ulcers Often associated with varicose veins Clinical evaluation Extrinsic venous[merckmanuals.com] During the first 24 hours of hospitalization, the pruritus and scrotal swelling worsened.[consultant360.com]

  • Venous Stasis Ulcer

    When this approach does not work, there is an increased risk of infection and may lead to cellulitis or gangrene and can result in amputation of the limb.[oceansidehyperbaric.ca] Location Venous stasis ulcer is basically located and found at the distal extremity, lower leg.[howshealth.com] Pruritus may accompany skin changes.[merckmanuals.com]

  • Livedo Reticularis

    Involvement of the blood vessels of the skin can give rise to livedo reticularis, acrocyanosis, ulcers, and gangrene.[ncbi.nlm.nih.gov] The discoloration typically affects the lower extremities. Many people describe the discoloration as having a net-like or lace appearance.[justanswer.com] […] erythrokeratodermas and related disorders Keratodermas Kro Dariers disease and HaileyHailey disease Daniel Hohl Theodora Mauro and leanPhilippe Gorog Mosaicism and linear lesions Pruritus[books.google.de]

  • Anicteric Viral Hepatitis

    Jaundice may develop in up to 20% of patients with gas gangrene.[wjgnet.com] A discoloration of the skin can be identified after the resolution of the exanthem, particularly on the lower extremities.[emedicine.medscape.com] Symptomatic Medications: -Trimethobenzamide (Tigan) 250 mg PO q6-8h prn pruritus or nausea q6-8h prn. -Hydroxyzine (Vistaril) 25 mg IM/PO q4-6h prn pruritus or nausea.[fprmed.com]

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