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36 Possible Causes for Discoloration of the Lower Extremity, Gangrene, Raynaud's Disease

  • Raynaud's Disease

    […] of the toes Gangrene of the fingertips Extreme constriction of blood vessels (peripheral) Tissue hypoxia Skin, muscle, and tissue atrophy Ulceration Ischemic gangrene Raynaud[] The primary Raynaud’s phenomenon is also known as the Raynaud’s disease.[] An examination revealed venous changes, chronic ulceration, and digit discoloration in upper and lower extremities.[]

  • Thromboangiitis Obliterans

    Human disease Buerger's disease Presenile gangrene Presenile gangrene (disorder) Thromboangiitis obliterans (disorder) Thromboangiitis obliterans NOS (disorder) Thromboangiitis[] […] syndrome Inclusion term(s): Raynaud's disease Raynaud's phenomenon (secondary) I73.00 Raynaud's syndrome without gangrene I73.01 Raynaud's syndrome with gangrene I73.1 Thromboangiitis[] extremities.[]

  • Erythromelalgia

    It is possible to get ulceration, necrosis and gangrene as complications of erythromelalgia.[] Raynaud's phenomenon is a vasospastic disorder resulting in ischaemia of fingers and toes precipitated by cold or stress.[] […] of the lower extremities ( Figure 3 ).[]

  • Thrombosis

    Examinations after death have shown that thrombosis exists for some distance around the gangrenous mass.[] A 60-year-old man with a history of Raynaud's phenomenon presented with bilateral intermittent claudication and an ulcer on his right toe.[] Patients with venous thrombosis may have variable discoloration of the lower extremity.[]

  • Calcinosis Cutis

    In very rare cases, Calcinosis Cutis can cause gangrene due to blockage of blood flow.[] The first was initially misdiagnosed as venous ulcerations; the second presented with a confirmed diagnoses of calcinosis cutis, Raynaud's disease, and scleroderma.[] They tend to be distributed bilaterally and symmetrically, and they are most commonly located on the lower extremities, which may relate to poor circulation, as well as the[]

  • Acrocyanosis

    Fournier's gangrene is a rare condition and delayed treatment results in fatal outcome. We managed a case of Fournier's gangrene by...[] […] forms are related to the Raynaud phenomenon.[] RP has a broad differential but is distinct from acrocyanosis and is differentiated by the waxing and waning of extremity discoloration.[]

  • Vascular Disease

    Myoglobinuria cleared with hydration and creatinine kinase levels returned to normal; however, the patient ultimately developed gangrene of both lower extremities.[] Also called: Raynaud's phenomenon Summary Raynaud's disease is a rare disorder of the blood vessels, usually in the fingers and toes.[] This is a prolonged condition in which one or more veins don’t adequately return blood from the lower extremities back to the heart due to damaged venous valves.[]

  • Lumbar Sympathectomy

    Two of the patients had actual gangrene of one or more toes. In 1 of these the pain was relieved and the temperature of the skin raised 10 C. (18 F.).[] OBJECTIVE: Livedo reticularis (LR) is a reticulated discoloration of the skin, particularly on lower extremities. Few treatment options are reported.[] But it is only advocated in the presence of ankle/arm indices above 0.30 and in the absence of gangrenous lesions.[]

  • Phlegmasia Cerulea Dolens

    OBJECTIVE: Phlegmasia cerulea dolens (PCD) and venous gangrene are limb and life-threatening conditions of iliofemoral acute deep vein thrombosis (DVT).[] Phenomenon 257 Hypercoagulable Conditions Leading to Limb Ischemia 267 Vasculitis 279 Cholesterol Emboli 292 Venous Etiologies of Acute Limb Ischemia 305 Malignant and Benign[] The patient returned to the Emergency Department a week later for worsening pain and bluish discoloration of her bilateral lower extremities.[]

  • Peripheral Vascular Disease

    Five SCI patients presented with lower extremity gangrene as the initial recognized manifestation of PVD at our institution between January 1992 and January 1994.[] Other diseases predispose patients to develop peripheral vascular disease. These include diabetes, Buerger's disease, hypertension, and Raynaud's disease.[] extremities back to the heart due to damaged venous valves.[]

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