Create issue ticket

13 Possible Causes for Discoloration of the Lower Extremity, Sclerodactyly

  • Raynaud's Disease

    An examination revealed venous changes, chronic ulceration, and digit discoloration in upper and lower extremities.[ncbi.nlm.nih.gov] Trophic changes of sclerodactyly and, rarely, fingertip ulcerations or gangrene,[jamanetwork.com] […] syndrome Rheumatoid arthritis Occlusive vascular disease Polymyositis Cryoglobulinemia CREST syndrome (Calcium skin deposits, Raynaud’s phenomenon, Esophageal dysmotility, Sclerodactyly[ucdmc.ucdavis.edu]

  • Thromboangiitis Obliterans

    extremities.[vasculardiseasemanagement.com] […] fasting blood sugar levels and sedimentation rate; tests for antinuclear antibody, rheumatoid factor, serologic markers for CREST (calcinosis cutis, Raynaud phenomenon, sclerodactyly[doi.org] The patient’s discomfort in the index finger quickly resolved, as did discoloration in the digit.[vasculardiseasemanagement.com]

  • Calcinosis Cutis

    They tend to be distributed bilaterally and symmetrically, and they are most commonly located on the lower extremities, which may relate to poor circulation, as well as the[cjasn.asnjournals.org] There was no Raynaud's phenomenon, dysphagia, dyspnoea, sclerodermatous skin, sclerodactyly, telangectasias, or muscle tenderness/weakness.[ncbi.nlm.nih.gov] A 71-year-old woman presented with calcinosis cutis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, and facial telangiectasias 20 years ago.[jrheum.org]

  • Nonallergic Interstitial Nephritis

    Sometimes, particularly after displacement of a large aortic plaque, marked ischemia of the lower extremities yields a bluish-purplish discoloration (ie, livedo reticularis[emedicine.medscape.com] […] creatin kinase (CK)クレアチンキナーゼ crepitant rale捻髪[様ラ]音 CREST syndromeCREST症候群、クレスト症候群〈CREST calcinosis cutis(石灰沈着)、Raynaud phenomenon(レイノー現象)、esophageal motility disorder(食道機能異常)、sclerodactyly[tokyo-med.ac.jp] In the syndrome CREST (acronym of “ Calcinosis, Raynaud ' phenomenon, Esophageal dysmotility, Sclerodactyly and Telangiectases ”) usually there is few renal involvement.[kidneypathology.com]

  • Livedo Reticularis

    The discoloration typically affects the lower extremities. Many people describe the discoloration as having a net-like or lace appearance.[justanswer.com] , bowel ischemia, and renal insufficiency developed following CO(2) angiography in a patient with CREST syndrome (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly[ncbi.nlm.nih.gov] OBJECTIVE: Livedo reticularis (LR) is a reticulated discoloration of the skin, particularly on lower extremities. Few treatment options are reported.[ncbi.nlm.nih.gov]

  • Bencze Syndrome

    A condition that is caused by recurring atheroembolism in the lower extremities.[connects.catalyst.harvard.edu] […] schisis, schistosomiasis, schizencephaly, schizophrenia, schlegelberger, schmid, schneckenbecken, schofer, schutz, schwannoma, scimitar, sclerae, scleroatonic, sclerocornea, sclerodactyly[rapsodyonline.eurordis.org] It is characterized by cyanotic discoloration of the toes, usually the first, fourth, and fifth toes. Discoloration may extend to the lateral aspect of the foot.[connects.catalyst.harvard.edu]

  • Nephritis

    Sometimes, particularly after displacement of a large aortic plaque, marked ischemia of the lower extremities yields a bluish-purplish discoloration (ie, livedo reticularis[emedicine.medscape.com] In the syndrome CREST (acronym of “ Calcinosis, Raynaud ' phenomenon, Esophageal dysmotility, Sclerodactyly and Telangiectases ”) usually there is few renal involvement.[kidneypathology.com] ) of the feet or lower portions of legs.[emedicine.medscape.com]

  • Lamellar Ichthyosis

    extremity macules, RA, splenomegaly, thrombocytopenia epidermal nevus s.[readbag.com] Other features include limitation of joint movements, flexion contractures, digital sclerodactyly, palmoplantar keratoderma, scarring alopecia and persistent ectropion, congenital[e-ijd.org] […] mechanoreceptors to vibrational stimuli PACK s. primary biliary cirrhosis, anti-centromere antibody, CREST (calcinosis cutis, Raynaud’s phenomenon, esophageal dysfunction, sclerodactyly[yumpu.com]

  • Cutaneous Lupus Erythematosus

    […] frequently on the lower extremities ( Figure 11 ) [ 79 ].[ncbi.nlm.nih.gov] The presence of anti-U1RNP antibodies is usually associated with sclerodactyly, esophageal dysmotility, a low incidence of kidney disease, pulmonary dysfunction, arthritis[scielo.br] It is characterized by erythematous or cyanotic discoloration of the skin with reticulated (net-like) pattern, usually on the lower extremities.[omicsgroup.org]

  • Pityriasis Rubra Pilaris

    Ichthyosiform lesions and areas of eczematous dermatitis, especially in the lower extremities, may be seen in the atypical adult and atypical juvenile variants.[clinicaladvisor.com] Systemic sclerosis is diagnosed on the basis of skin thickening, sclerodactyly, acroosteolysis and presence of anti-nucleolar antibodies, although there was no evidence of[panafrican-med-journal.com] Nail changes are frequent and include nail plate thickening, yellow-brown discoloration, and splinter hemorrhages (Figure 6).[clinicaladvisor.com]

Further symptoms

Similar symptoms