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158 Possible Causes for Disorder of Digit, Narrow Hands, Thrombophilia

  • Puerperium

    Genetic polymorphisms associated with thrombophilia such as factor V Leiden, prothrombin G20210A, MTHFR C677T, ACE and PIA1/A2 may be the cause of the hypercoagulability that[] Includes: the listed conditions during pregnancy, childbirth, or the puerperium 676 Other disorders of the breast associated with childbirth and disorders of lactation Requires[] But within the first day the cervix has usually narrowed and regained its normal muscular consistency.[]

  • Raynaud Phenomenon

    Google Scholar Walker ID: Thrombophilia in pregnancy. J Clin Pathol. 2000, 53 (8): 573-80. 10.1136/jcp.53.8.573.[] Raynaud's (say "ray-NOHZ") phenomenon is a problem when the blood vessels in the hands and feet are extra sensitive and become more narrow than normal.[] BACKGROUND: Raynaud phenomenon (RP) is a vasospastic disorder of the digital arteries. Severe forms are found in patients with connective tissue diseases.[]

  • Raynaud's Disease

    Google Scholar Walker ID: Thrombophilia in pregnancy. J Clin Pathol. 2000, 53 (8): 573-80. 10.1136/jcp.53.8.573.[] Abstract Raynaud's disease is a common vasospastic disorder affecting the digits of both hands. Women are most commonly affected.[] When you are cold or stressed, the arteries in your extremities (fingers, hands, feet, toes) narrow, or constrict.[]

  • Arterial Thrombosis

    Laboratory tests for thrombophilia revealed the presence of a G20210A prothrombin gene mutation.[] Despite that they did not have features suggestive of disorders like Scleroderma or CREST syndrome.[] Some people get chest pains (angina) , which are a sign that atherosclerosis has narrowed the coronary arteries.[]

  • Acrocyanosis

    Similarly, there is no need to work up the patient with acrocyanosis for a clotting disorder (thrombophilia), as finding a thrombophilia would not have any treatment consequences[] digits on exposure to cold, that occurs in episodic attacks.[] Considered a vasospastic disorder, it affects the arteries supplying blood to the skin of the hands and feet.[]

  • Ischemic Peripheral Neuropathy

    Boekholdt SM, Kramer MH (2007) Arterial thrombosis and the role of thrombophilia.[] , short digits, and weak muscles.[] […] strokes are described by the 5 most common lacunar syndromes: pure motor hemiparesis, sensorimotor stroke, ataxic hemiparesis, pure sensory stroke, and dysarthria-clumsy hand[]

  • Vasculitis

    Thrombophilia screening finds a blood lupus anticoagulant. A biopsy of subcutaneous nodes finds an anatomopathologic lesion of polyarteritis nodosa.[] Buerger's disease In Buerger’s disease (BGD), or thromboangiitis obliterans, small blood vessels in the hands and feet become inflamed and narrowed.[] PubMed, J Vasc Surg Venous Lymphat Disord, 2017 Mar;5(2):280-292. (Also see Treatments for Digital Ulcers ) Clinical Trials in Vasculitis.[]

  • Laron Syndrome with Immunodeficiency

    […] due to congenital protein C deficiency Thrombophilia 1 0 Thrombophilia due to thrombin defect Thrombophilia 1 0 Thrombophilia, X-linked, due to factor IX defect Thrombophilia[] Neonatal lymphedema, heart malformations, aplasia cutis congenita, aortic root dilatation, and autistic spectrum disorder have also been reported.[] H00220 Factor V deficiency [PATH: hsa04610 ] H00221 Combined deficiency of factors V and VIII [PATH: hsa04141 ] H00222 Afibrinogenemia [PATH: hsa04610 ] H00223 Inherited thrombophilia[]

  • Hereditary Hyperekplexia

    Diamond-Blackfan Anemia Dyskeratosis Congenita ELANE-Related Neutropenia Fanconi Anemia GATA1-Related X-Linked Cytopenia WAS-Related Disorder Hereditary Hemochromatosis Hereditary Thrombophilia[] Acromicric dysplasia is a rare bone dysplasia characterized by short stature, short hands and feet, mild facial dysmorphism, and characteristic X-ray abnormalities of the hands[] […] hereditary hemorrhagic PS187300 Thiamine-responsive dysfunction syndrome PS249270 Thiopurines, poor metabolism of PS610460 Three M syndrome PS273750 Thrombocythemia PS187950 Thrombophilia[]

  • Thromboangiitis Obliterans

    Lupus anticoagulant and anticardiolipin antibodies are detected in some patients with thromboangiitis obliterans but may also indicate an isolated thrombophilia.[] A 25-year-old woman with progressive Raynaud's phenomenon and digital necrosis is presented.[] The blood vessels then narrow or get blocked by blood clots (thrombosis). Blood vessels of the hands and feet are mostly affected. Arteries are more affected than veins.[]

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