Create issue ticket

96 Possible Causes for Disseminated Intravascular Coagulation, Irinotecan, Peripheral Neuropathy

  • Adenocarcinoma of the Colon

    Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal .N Engl J Med 2004;351:337-45. 13. T. Delaunoit1, S.R. Alberts, D.J.[scielo.mec.pt] It requires laparotomy and can potentially results in significant morbidity, including liver cracking, thrombocytopenia, and disseminated intravascular coagulation (DIC).[emedicine.medscape.com] Patients who received FOLFOXIRI had significantly more grade 3 and 4 toxicities, including neutropenia, stomatitis, and peripheral neuropathy.[cancer.gov]

  • Pancreatic Adenocarcinoma

    Options for front-line therapy include both infusional 5-fluorouracil, leucovorin, irinotecan, oxaliplatin (FOLFIRINOX) and the combination of gemcitabine plus nab-paclitaxel[ncbi.nlm.nih.gov] The main adverse effects are peripheral neuropathy, neutropenia, thrombocytopenia and fatigue.[nature.com] […] in patients in a very good health condition, two recent intensive chemotherapies can be proposed with modified doses and a close follow-up: the 5-fluoroucil, leucovorin, irinotecan[ncbi.nlm.nih.gov]

  • Cecal Adenocarcinoma

    Irinotecan 24,25 Days 1 and 8: Irinotecan 125mg/m 2 IV over 30–90 minutes. Repeat cycle every 3 weeks. OR Day 1: Irinotecan 300–350mg/m 2 IV over 30–90 minutes.[cancertherapyadvisor.com] intravascular coagulation 播種性血管内凝固症候群 disseminated metastasis of the peritoneum腹膜播種性転移 distal gastrectomy幽門側胃切除術 distal pancreatectomy尾側膵切除術 distention of stomach胃拡張 diverticula[tokyo-med.ac.jp] Patients who received FOLFOXIRI had significantly more grade 3 and 4 toxicities, including neutropenia, stomatitis, and peripheral neuropathy.[cancer.gov]

  • Gastric Adenocarcinoma

    ., 5-FU (5 μ M); cisplatin (0.5 μ M); irinotecan (2.5 μ M); carboplatin (5 μ M); paclitaxel (2-4 n M); and X rays (1.8 Gy)] also potentiated gastric cancer clonogenic cell[ncbi.nlm.nih.gov] The patient died in disseminated intravascular coagulation context.[ncbi.nlm.nih.gov] neuropathy grade 2 Inability to tolerate intravenous hydration e.g due to cardiac disease Co-morbidities (based on clinical judgement by the investigator) that in the view[clinicaltrials.gov]

  • Adenocarcinoma of the Ovary

    The 50% growth inhibitory concentrations (IC50) (nM) of various anticancer drugs were: cisplatin 10,000, paclitaxel 80, SN-38 (irinotecan metabolite) 460, and gemcitabine[ncbi.nlm.nih.gov] Combination chemotherapy with irinotecan hydrochloride plus cisplatin has been reported to be effective for primary and recurrent or resistant CCC.[ncbi.nlm.nih.gov] She had recurrent tumors after primary cytoreductive surgery, which were unresectable and also resistant to paclitaxel, carboplatin, irinotecan, and oral etoposide.[ncbi.nlm.nih.gov]

  • Bronchogenic Carcinoma

    Etoposide, carboplatin, cislatin or irinotecan are recommended chemotherapeutic agents.[symptoma.com] . · Anaemia, disseminated intravascular coagulation, thrombotic thrombocytopenic purpura.[syrianclinic.com] neuropathy, acanthosis nigricans, and hypertrophic osteoarthropathy (Example: clubbing of fingers).[histopathology-india.net]

  • Paraneoplastic Syndrome

    He was then switched to cisplatin and irinotecan with good response and completed five cycles.[healio.com] Disseminated intravascular coagulation secondary to metastatic prostate cancer: case report and review of the literature. Arch. Ital. Urol.[doi.org] Abstract POEMS (peripheral neuropathy, organomegaly, endocrinopathy, M protein, skin changes) syndrome is a rare multisystem paraneoplastic disorder.[ncbi.nlm.nih.gov]

  • Bronchial Adenocarcinoma

    Targeted therapy with drugs such as paclitaxel, carboplatin, irinotecan, and erlotinib has also shown results.[medical-dictionary.thefreedictionary.com] neuropathy, acanthosis nigricans, and hypertrophic osteoarthropathy (Example: clubbing of fingers).[histopathology-india.net] Paraneoplastic syndrome• Lambert-Eaton syndrome• Peripheral neuropathy• Acanthosis nigricans• Leukemoid reaction• Hypertrophic pulmonary osteoarthropathy• Horner syndrome•[slideshare.net]

  • Multiple Myeloma

    Ishida, Hirokazu Komatsu, Hiroshi Inagaki, Atsushi Suzuki and Ryuzo Ueda, Overexpression of carboxylesterase‐2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan[doi.org] The mechanism of the development of the peripheral neuropathy is poorly understood.[ncbi.nlm.nih.gov] BACKGROUND: Based on the possible shared mechanisms of chemotherapy-induced peripheral neuropathy (CIPN) for different drugs, we aimed to aggregate results of all previously[ncbi.nlm.nih.gov]

  • Esophageal Carcinoma

    Enzinger PC, Clark J, Bryan D et al. (2004) Phase II study of docetaxel, cisplatin, and irinotecan in advanced esophageal and gastric cancer.[springermedizin.de] Physicians' Choice of Single Agent Docetaxel, Paclitaxel, or Irinotecan in Subjects with Advanced/Metastatic Adenocarcinoma...[clinicaltrialsregister.eu] Types of chemotherapy: 5-fluorouracil, capecitabine, cisplatin, carboplatin, docetaxel, bleomycin, mitomycin, doxorubicin, methotrexate, paclitaxel, vinorelbine, topotecan, irinotecan[medical-dictionary.thefreedictionary.com]

Similar symptoms