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13 Possible Causes for Disturbance of Coordination, Interictal Downbeat Nystagmus, Nystagmus

  • Acute Cerebellar Ataxia

    . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] A 54-year-old woman with adenocarcinoma of the lung and lymph node metastasis experienced nystagmus and cerebellar ataxia 2 weeks after initiating nivolumab therapy.[ncbi.nlm.nih.gov] It is the sudden onset of a disturbance in coordination. The cerebellum is the part of the brain that plays an important role in balance and coordination.[cookchildrens.org]

  • Episodic Ataxia

    According to Baloh and others (1997), EA2 is characterized by a progressive ataxia with interictal rebound nystagmus evoked by gaze, as well as downbeating nystagmus.[dizziness-and-balance.com] Between attacks they have nystagmus and dysarthria. These patients are responsive to acetazolamide.[en.wikipedia.org] Ataxia is characterized by disturbances in the voluntary coordination of posture and movement.[healio.com]

  • Alcoholic Cerebellar Degeneration

    . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] […] thiamine deficiency Alterations in GABA receptor dependent neurotransmission have also been proposed as a pathogenic mechanism Clinical features Truncal ataxia Unsteady gait Nystagmus[pathologyoutlines.com] […] ataxia of gait, and truncal instability, with generally preserved coordination of the upper extremities.[ncbi.nlm.nih.gov]

  • Spinocerebellar Ataxia Type 6

    Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] The proband presented with periodic alternating nystagmus (PAN), and her 2 brothers had rebound nystagmus and gaze-evoked nystagmus.[ncbi.nlm.nih.gov] The result is a lack of coordination and balance, or disturbance in their gait.[disabled-world.com]

  • Autosomal Recessive Spinocerebellar Ataxia 8

    According to Baloh and others (1997), EA2 is characterized by a progressive ataxia with interictal rebound nystagmus evoked by gaze, as well as downbeating nystagmus.[tchain.com] Findings on examination include spastic and ataxic dysarthria, gaze-evoked nystagmus, limb and gait ataxia, limb spasticity, and diminished vibratory sensation.[ataxia.uchicago.edu] The result is a lack of coordination and balance, or disturbance in their gait.[disabled-world.com]

  • Cerebellar Ataxia with Peripheral Neuropathy Type 2

    . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] Also observed were moderate incidences of horizontal eye dysmetria, rebound nystagmus, vertical positional nystagmus and visual suppression.[tinnitusjournal.com] Cortical Ataxias  FRONTAL LOBE ATAXIA refers to disturbed coordination due to dysfunction of the contralateral frontal lobe; -Results from disease involving the frontopontocerebellar[slideshare.net]

  • Adult-Onset Autosomal Recessive Cerebellar Ataxia

    . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] Spinocerebellar ataxia 1 See the list below: Clinical features Onset in the fourth decade of life Gait ataxia, dysarthria, dysmetria, nystagmus, peripheral neuropathy, muscle[emedicine.medscape.com] The result is a lack of coordination and balance, or disturbance in their gait.[disabled-world.com]

  • Early-Onset Cerebellar Ataxia

    . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] Frequencies of symptoms and signs were also comparable for both groups the only significant differences being the higher frequency of nystagmus, cardiomyopathy and sensory[ncbi.nlm.nih.gov] The result is a lack of coordination and balance, or disturbance in their gait.[disabled-world.com]

  • Spinocerebellar Ataxia Type 4

    Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] […] well-known disease symptoms of SCA4 patients (i.e. ataxic symptoms, dysarthria and somatosensory deficits), but for the first time help to explain why diplopia, gaze-evoked nystagmus[ncbi.nlm.nih.gov] The result is a lack of coordination and balance, or disturbance in their gait.[disabled-world.com]

  • Spinocerebellar Ataxia with Rigidity and Peripheral Neuropathy

    . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] […] more bizzare forms of nystagmus can also be seen eg. periodic alternating nystagmus, pendular nystagmus, divergent nystagmus, pure torsional nystagmus on vertical gaze (*[lifeinthefastlane.com] Cortical Ataxias  FRONTAL LOBE ATAXIA refers to disturbed coordination due to dysfunction of the contralateral frontal lobe  Results from disease involving the frontopontocerebellar[slideshare.net]

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