Create issue ticket

683 Possible Causes for Disturbance of Growth, Hepatomegaly

  • Thalassemia

    Figure 1 Probability of OS by age and hepatomegaly. Figure 2 Probability of DFS by age and hepatomegaly.[doi.org] Because of the decreased, and often pathological erythrocytes, hypoxia becomes clinically relevant as growth disturbances and trophic skin changes show in child age. α-Thalassemia[lecturio.com] As hypersplenism may cause worsening anemia, retarded growth and mechanical disturbance from the large spleen, splenectomy is a relevant aspect of the management of thalassemia[doi.org]

  • Progressive Familial Intrahepatic Cholestasis

    RESULTS: All four patients were presented with jaundice, pruritus, hepatomegaly, sleep disturbance. They fulfilled the criteria for PFIC. The surgery was uneventful.[ncbi.nlm.nih.gov] Both patients had normal gamma-glutamyl transpeptidase levels, but showed severe pruritus with sleep disturbance, cholestasis, jaundice and growth failure.[ncbi.nlm.nih.gov] Clinical signs of cholestasis (discolored stools, dark urine) usually appear in the first months of life with recurrent or permanent jaundice associated with hepatomegaly[orpha.net]

  • Chronic Alcoholism

    Hepatomegaly (in chronic alcoholic liver disease the liver is shrunken). Ascites; gonadal atrophy. Atrial fibrillation and cardiomyopathy.[patient.info] Alcohol consumption disturbs hormones of the body, impairs the function of the glands and signaling of messages to the brain.[epainassist.com] Characteristic ultrasonographic findings include a hyperechoic liver with or without hepatomegaly.[clevelandclinicmeded.com]

  • Toxoplasmosis

    Toxoplasmosis is only one of the putative infectious agents that derange correct brain growth and differentiation, alongside genetic and environmental factors.[ncbi.nlm.nih.gov] […] common encephalomyelitis, retinochoroiditis, intracranial calcification and hydrocephalus to the non-specific symptoms of acute infection such as convulsion, splenomegaly, hepatomegaly[fao.org] There may be ventriculomegaly, CNS calcifications, placental changes, hepatomegaly, splenomegaly, ascites and pericardial or pleural effusion [ 3 ] .[patient.info]

  • Diabetes Mellitus

    Abstract Glycogenic hepatopathy is a rare condition that causes significant hepatomegaly and elevated liver enzyme levels in uncontrolled type 1 diabetic patients.[ncbi.nlm.nih.gov] Hormonal disturbances Diabetes can also result from other hormonal disturbances, such as excessive growth hormone production (acromegaly) and Cushing's syndrome.[medicinenet.com] Children with diabetic dwarfism syndrome, which was also known as Mauriac's syndrome, suffered from stunted growth, hepatomegaly, and delayed puberty. 4 In 1936, the first[spectrum.diabetesjournals.org]

  • Hemochromatosis

    The main adverse effects are inflammatory reactions at the sites of injection, visual and auditory disturbances, bone growth disturbances, and allergic reactions, including[physio-pedia.com] […] transferrin saturation (TS); ALT; AST; GGT; elevated C-reactive protein; ß-thalassemia; neutrophils; lymphocytes; monocytes; platelets; metacarpophalangeal joint hypertrophy; hepatomegaly[ncbi.nlm.nih.gov] Eight of the 16 homozygous subjects had clinical findings that were consistent with the presence of hereditary hemochromatosis, such as hepatomegaly, skin pigmentation, and[ncbi.nlm.nih.gov]

  • Congestive Heart Failure

    Right upper quadrant sonogram revealed hepatomegaly of 15 cm, trace amount of perihepatic ascites, pericholecystic fluid, and also thickened edematous gallbladder wall with[ncbi.nlm.nih.gov] Cardiomyopathy can also be seen in babies and can be due to a number of problems such as rhythm disturbances or infections.[cincinnatichildrens.org] Cardiac examination at the age of 6 years revealed constrictive pericarditis with significant elevation of atrial filling pressures, consecutive hepatomegaly, and protein[ncbi.nlm.nih.gov]

  • Congenital Generalized Lipodystrophy Type 2

    Disease definition Berardinelli-Seip congenital lipodystrophy (BSCL) is characterized by the association of lipoatrophy, hypertriglyceridemia, hepatomegaly and acromegaloid[orpha.net] Hepatomegaly and splenomegaly may be found during the postnatal examination and may provoke umbilical prominence or even an umbilical hernia.[symptoma.com] Complications include hypertrophic cardiomyopathy, a fatty liver with hepatic dysfunction, muscular hypertrophy, a number of endocrine disturbances (accelerated growth in[orpha.net]

  • Chronic Right-Sided Congestive Heart Failure

    Right sided heart failure Right sided heart failure Right sided heart failure Right sided heart failure Anasarca (massive generalized body edema) Right sided heart failure Hepatomegaly[quizlet.com] Cardiomyopathy can also be seen in babies and can be due to a number of problems such as rhythm disturbances or infections.[cincinnatichildrens.org] Abdominal examination elicited pain during superficial palpation on the right upper quadrant with hepatomegaly identification, with no signs of ascites.[austinpublishinggroup.com]

  • Hepatoblastoma

    Abdominal magnetic resonance findings revealed hepatomegaly with multiple tumor masses involving nearly all the segments of the liver (PRETEXT IV).[ncbi.nlm.nih.gov] Antecedent growth disturbance of liver, either intrinsic, (abnormal lobation) or related to contiguous extrinsic anomalies such as omphalocele or local diaphragmatic hypoplasia[tandfonline.com] Virtually all patients were infants or young children with hepatomegaly or a mass.[pubs.rsna.org]

Further symptoms

Similar symptoms