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907 Possible Causes for Disturbance of Growth, Hypogonadism

  • Thalassemia

    Because of the decreased, and often pathological erythrocytes, hypoxia becomes clinically relevant as growth disturbances and trophic skin changes show in child age. α-Thalassemia[lecturio.com] RESULTS: We found that females were more anemic than males, but there was no significant difference in prevalence of common complications among genders, except for hypogonadism[ncbi.nlm.nih.gov] As hypersplenism may cause worsening anemia, retarded growth and mechanical disturbance from the large spleen, splenectomy is a relevant aspect of the management of thalassemia[doi.org]

  • Cystinosis

    Growth retardation improved after correction of electrolyte disturbances, the initiation of cysteamine therapy and treatment with recombinant human growth hormone.[ncbi.nlm.nih.gov] Clinically the disorder shows a slowly progressive glomerular insufficiency rather than the prominent Fanconi syndrome, electrolyte and water disturbances, growth arrest,[ncbi.nlm.nih.gov] , hypogonadism and infertility Second or third decade of life: Retinal damage Third decade of life: Cerebral calcifications; muscular and swallowing difficulties Laboratory[emedicine.medscape.com]

  • Hemochromatosis

    The main adverse effects are inflammatory reactions at the sites of injection, visual and auditory disturbances, bone growth disturbances, and allergic reactions, including[physio-pedia.com] Table 5 compares the hypogonadal males to the nonhypogonadal males.[academic.oup.com] KEYWORDS: Diabetes; Hereditary hemochromatosis; Hypogonadism; Pituitary defects[ncbi.nlm.nih.gov]

  • Klinefelter Syndrome

    Aberrant imprinting disturbs development and is the cause of various disease syndromes.[dx.doi.org] Site-specific effect of testosterone on bone mineral density in male hypogonadism.[ncbi.nlm.nih.gov] Small testes, hypergonadothrophic hypogonadism and cognitive impairment are usually found.[ncbi.nlm.nih.gov]

  • Endocrine Dysfunction

    […] can include growth hormone deficiency, hypogonadism, adrenal dysfunction, hypoparathyroidism and thyroid disease.[ncbi.nlm.nih.gov] Hypogonadic females had a significantly elevated mean serum ferritin level.[ncbi.nlm.nih.gov] Insulin plays a central role in metabolic regulation, but its actions are modified or balanced by those of many other hormones, including glucagon, growth hormone, corticosteroids[diapedia.org]

  • Luteinizing Hormone Deficiency

    Growth hormone (GH) deficiency refers to inadequate levels of GH (and therefore IGF-1), resulting in growth retardation in children and metabolic disturbances in adults.[healthcentral.com] Male hypogonadism due to a mutation in the gene for the beta-subunit of follicle-stimulating hormone. N Engl J Med. 1998 Jun 11. 338(24):1729-32. [Medline].[emedicine.medscape.com] Note that symptoms related to mass effect from a lesion are also key historical elements and commonly manifest as visual field disturbances and headaches.[clinicaladvisor.com]

  • Craniopharyngioma

    The onset of symptoms is normally insidious with most patients at diagnosis having neurological (headaches, visual disturbances) and endocrine (growth retardation, delayed[ncbi.nlm.nih.gov] Complications included panhypopituitarism including growth hormone deficiency and hypogonadism at 13 years old.[ncbi.nlm.nih.gov] Clinical description The onset of symptoms is normally insidious with most patients at diagnosis having neurological (headaches, visual disturbances) and endocrine (growth[orpha.net]

  • Brandt Syndrome

    Diarrhoea, mood changes, anorexia, and neurological disturbance were reported most frequently in infancy.[ncbi.nlm.nih.gov] Other features associated with severe and chronic zinc deficiency include failure to thrive, mental slowness, photophobia, hypogeusia, anemia, poor wound healing, hypogonadism[orpha.net] AE is associated with short stature, anaemia, skin hyperpigmentation, hepatosplenomegaly, hypogonadism, poor wound healing, immune deficiency, recurrent bacterial and fungal[medical-dictionary.thefreedictionary.com]

  • Prader-Willi Syndrome

    In Prader-Willi syndrome (PWS) hypothalamic dysfunction is the cause of hormonal disturbances, such as growth hormone deficiency (GHD), hypogonadism, and delayed or incomplete[ncbi.nlm.nih.gov] Clinical manifestations include mental retardation; muscular hypotonia; hyperphagia; obesity; short stature; hypogonadism; strabismus; and hypersomnolence.[icd9data.com] , growth hormone deficiency, and hypogonadism, and also altered pain threshold and inability to vomit, pose unique issues.[ncbi.nlm.nih.gov]

  • Gordon Holmes Syndrome

    […] failure, mental retardation, generalized weakness, and disturbed pubertal development [ 17 ].[journals.plos.org] Further, our data reveal the second STUB1 family with ataxia plus hypogonadism reported so far, demonstrating that Gordon Holmes syndrome is indeed a recurrent manifestation[ncbi.nlm.nih.gov] ; decline in general feeling of well-being Psychological: Depression/depressed mood; mood changes; irritability; inability to concentrate; insomnia/sleep disturbances In the[cmaj.ca]

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