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907 Possible Causes for Disturbance of Growth, Hypogonadism

  • Thalassemia

    Because of the decreased, and often pathological erythrocytes, hypoxia becomes clinically relevant as growth disturbances and trophic skin changes show in child age. α-Thalassemia[] RESULTS: We found that females were more anemic than males, but there was no significant difference in prevalence of common complications among genders, except for hypogonadism[] As hypersplenism may cause worsening anemia, retarded growth and mechanical disturbance from the large spleen, splenectomy is a relevant aspect of the management of thalassemia[]

  • Cystinosis

    Growth retardation improved after correction of electrolyte disturbances, the initiation of cysteamine therapy and treatment with recombinant human growth hormone.[] Clinically the disorder shows a slowly progressive glomerular insufficiency rather than the prominent Fanconi syndrome, electrolyte and water disturbances, growth arrest,[] , hypogonadism and infertility Second or third decade of life: Retinal damage Third decade of life: Cerebral calcifications; muscular and swallowing difficulties Laboratory[]

  • Hemochromatosis

    The main adverse effects are inflammatory reactions at the sites of injection, visual and auditory disturbances, bone growth disturbances, and allergic reactions, including[] Table 5 compares the hypogonadal males to the nonhypogonadal males.[] KEYWORDS: Diabetes; Hereditary hemochromatosis; Hypogonadism; Pituitary defects[]

  • Klinefelter Syndrome

    Aberrant imprinting disturbs development and is the cause of various disease syndromes.[] Site-specific effect of testosterone on bone mineral density in male hypogonadism.[] Small testes, hypergonadothrophic hypogonadism and cognitive impairment are usually found.[]

  • Endocrine Dysfunction

    […] can include growth hormone deficiency, hypogonadism, adrenal dysfunction, hypoparathyroidism and thyroid disease.[] Hypogonadic females had a significantly elevated mean serum ferritin level.[] Insulin plays a central role in metabolic regulation, but its actions are modified or balanced by those of many other hormones, including glucagon, growth hormone, corticosteroids[]

  • Luteinizing Hormone Deficiency

    Growth hormone (GH) deficiency refers to inadequate levels of GH (and therefore IGF-1), resulting in growth retardation in children and metabolic disturbances in adults.[] Male hypogonadism due to a mutation in the gene for the beta-subunit of follicle-stimulating hormone. N Engl J Med. 1998 Jun 11. 338(24):1729-32. [Medline].[] Note that symptoms related to mass effect from a lesion are also key historical elements and commonly manifest as visual field disturbances and headaches.[]

  • Craniopharyngioma

    The onset of symptoms is normally insidious with most patients at diagnosis having neurological (headaches, visual disturbances) and endocrine (growth retardation, delayed[] Complications included panhypopituitarism including growth hormone deficiency and hypogonadism at 13 years old.[] Clinical description The onset of symptoms is normally insidious with most patients at diagnosis having neurological (headaches, visual disturbances) and endocrine (growth[]

  • Brandt Syndrome

    Diarrhoea, mood changes, anorexia, and neurological disturbance were reported most frequently in infancy.[] Other features associated with severe and chronic zinc deficiency include failure to thrive, mental slowness, photophobia, hypogeusia, anemia, poor wound healing, hypogonadism[] AE is associated with short stature, anaemia, skin hyperpigmentation, hepatosplenomegaly, hypogonadism, poor wound healing, immune deficiency, recurrent bacterial and fungal[]

  • Prader-Willi Syndrome

    In Prader-Willi syndrome (PWS) hypothalamic dysfunction is the cause of hormonal disturbances, such as growth hormone deficiency (GHD), hypogonadism, and delayed or incomplete[] Clinical manifestations include mental retardation; muscular hypotonia; hyperphagia; obesity; short stature; hypogonadism; strabismus; and hypersomnolence.[] , growth hormone deficiency, and hypogonadism, and also altered pain threshold and inability to vomit, pose unique issues.[]

  • Gordon Holmes Syndrome

    […] failure, mental retardation, generalized weakness, and disturbed pubertal development [ 17 ].[] Further, our data reveal the second STUB1 family with ataxia plus hypogonadism reported so far, demonstrating that Gordon Holmes syndrome is indeed a recurrent manifestation[] ; decline in general feeling of well-being Psychological: Depression/depressed mood; mood changes; irritability; inability to concentrate; insomnia/sleep disturbances In the[]

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