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116 Possible Causes for Diurnal Fluctuation of Symptoms, 'Eye of the Tiger' Sign on MRI

  • Aromatic L-Amino Acid Decarboxylase Deficiency

    Diurnal fluctuation or improvement of symptoms after sleep were noted in half of the patients. Treatment response was variable.[] […] of the tigersign on MRI.[] FTL PANK2 PLA2G6 WDR45 Neurodegeneration with brain iron accumulation ( NBIA ) is a group of disorders characterized by iron accumulation in the basal ganglia causing the “eye[]

  • Hallervorden-Spatz Syndrome

    Iron deposition in conjunction with destruction of the globus pallidus gives rise to the characteristic eye-of-the-tiger sign in MRI.[] […] of the tiger" sign.[] It has been postulated that pantothenate kinase 2 mutations underlying all cases of classic Hallervorden-Spatz syndrome are always associated with the eye-of-the-tiger sign[]

    Missing: Diurnal Fluctuation of Symptoms
  • 6-Pyruvoyl-Tetrahydropterin Synthase Deficiency

    fluctuation of symptoms.[] […] with marked diurnal fluctuation.[] […] gressive dystonia-Diurnal fluctuation.[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Juvenile Paralysis Agitans of Hunt

    Patients with parkin mutations may have atypical clinical features such as dystonia at onset and marked diurnal symptom fluctuation; the disorder may bear some relationship[] Parkinsonismo precoce associado a lesões palidais de tipo "eye-of-the-tiger" "Eye-of-the-tiger" sign at MRI in a patient with early-onset parkinsonism Egberto Reis Barbosa[] […] without marked diurnal fluctuations and without heritance, but with a steady progress in spite of a certain answer on levodopa treatment.[]

  • Scoliosis

    Segawa's syndrome or dopa-responsive dystonia is a rare hereditary disorder characterized by progressive dystonia of childhood onset, diurnal fluctuation of symptoms and complete[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Neurodegeneration with Brain Iron Accumulation

    Individuals with PKAN and HARP syndrome, which is considered part of the PKAN disease spectrum, show a characteristic "eye of the tiger''sign on MRI, a central region of hyperintensity[] sign in cranial MRI, this case most likely represented an idiopathic form of NBIA but atypical PKAN may be also considered.[] For all of the disorders in this category, T 2 -weighted brain MRI would distinguish PKAN based on the presence of the "eye of the tiger" sign.[]

    Missing: Diurnal Fluctuation of Symptoms
  • Endogenous Depression

    A positive correlation was found between the number of anancastic personality features and the following symptoms: agitation, anxiety, diurnal fluctuation, seasonal variation[] The pattern of the anancastic symptoms was rather uniform; aggressive obsessions, mostly in the form of suicidal and homicidal obsessions, were present in more than two thirds[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Chronic Fatigue Syndrome

    Finally, diurnal fluctuations in ME/CFS tend to show symptom-worsening in the afternoon while in major depressive disorder more severe symptoms often occur in the morning.[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Adult-Onset Cervical Dystonia Type DYT23

    Hanihara T, Inoue K, Kawanishi C et al (1997) 6-Pyruvoyl-tetrahydropterin synthase deficiency with generalized dystonia and diurnal fluctuation of symptoms: a clinical and[] fluctuation of symptoms, and a dramatic and sustained response to levodopa [ 36 ].[] These symptoms show marked diurnal fluctuations, worsening through the day and almost absent in the early morning.[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Pallidopyramidal Syndrome

    Paralysis agitans of early onset with marked diurnal fluctuation of symptoms.[]

    Missing: 'Eye of the Tiger' Sign on MRI

Further symptoms

Similar symptoms