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73 Possible Causes for Dofetilide, Premature Ventricular Contraction

  • Atrial Fibrillation

    We report a case of dofetilide associated Bell's palsy masquerading as stroke that developed shortly after a cardioversion.[ncbi.nlm.nih.gov] ., chronic obstructive pulmonary disease (COPD) Premature atrial contractions (PACs) associated with alcohol, caffeine, and nicotine use Atrial flutter Wolff-Parkinson-White[medbullets.com] When the abnormal rhythm is normalized after electrical cardioversion, patients are often given antiarrhythmic drugs like flecainide, propafenone, dofetilide, and amiodarone[symptoma.com]

  • Congestive Heart Failure

    Dofetilide in patients with congestive heart failure and left ventricular dysfunction. Danish Investigations of Arrhythmia and Mortality on Dofetilide Study Group.[doi.org] Subsequent analysis revealed that the monitoring function had detected the arrhythmia as frequent premature ventricular contraction, although the arrhythmia did not trigger[ncbi.nlm.nih.gov] HRV measures and premature ventricular contraction (PVC) counts were compared between participants with (n 260) and without (n 1,141) incident CHF on follow-up.[ncbi.nlm.nih.gov]

  • Hypertrophic Cardiomyopathy

    (Level of Evidence: C) Class IIb Sotalol, dofetilide, and dronedarone might be considered alternative antiarrhythmic agents in patients with HCM, especially in those with[doi.org] Premature ventricular contractions (PVCs) and runs of non-sustained ventricular tachycardia (NSVT) reached a peak in the second and third trimesters, concurrent with sympathetic[ncbi.nlm.nih.gov] ., and Gustav Eles, D.O. 1 Citing Article A 68-year-old woman presented with symptoms of palpitations and was found to have frequent premature ventricular contractions and[nejm.org]

  • Ventricular Bigeminy

    […] shown to be typically deleterious in patients with coronary artery disease, this literature is not current, and specifically the role of newer class III antiarrhythmic like dofetilide[emedicine.medscape.com] […] introduction a premature ventricular contraction or ventricular ectopic beat is a cardiac contraction that is generally premature or occurs before the expected sinus QRS complex[ozemedicine.com] ., flecainide [Tambocor], dofetilide [Tikosyn], sotalol [Betapace], quinidine) TABLE 1 Causes of Ventricular Arrhythmias Cardiac causes Acute and chronic ischemic heart disease[aafp.org]

  • Premature Ventricular Contraction

    Dofetilide in patients with congestive heart failure and left ventricular dysfunction. Danish Investigations of Arrhythmia and Mortality on Dofetilide Study Group.[doi.org] How common are premature ventricular contractions? Premature ventricular contractions are common.[medicinenet.com] , and progression to ventricular tachycardia in children with frequent premature ventricular contractions.[ncbi.nlm.nih.gov]

  • Cardiac Arrhythmia

    […] particular focus on class Ia (quinidine, procainamide) and Ic (flecainide) Na channel blockers, and class III antiarrhythmic agents that block the delayed rectifier K channel (dofetilide[ncbi.nlm.nih.gov] Frequent premature ventricular contractions (PVCs) were found initially following the cardiac insult that was controlled with oral amiodarone, and disappeared during follow-up[ncbi.nlm.nih.gov] After 2000, methadone was the second-most common primary suspect in cases of QTc prolongation or torsade de pointes after dofetilide (a known proarrhythmic drug) and was associated[ncbi.nlm.nih.gov]

  • Torsades De Pointes

    Dofetilide prolongs the effective refractory period in accessory pathways, both anterograde and retrograde.[doi.org] BACKGROUND: Ventricular fibrillation may be caused by premature ventricular contractions (PVCs) whose coupling intervals are OBJECTIVE: The purpose of this study was to analyze[ncbi.nlm.nih.gov] (b) The initiating premature ventricular contraction occurs before the T-wave peak of the last beat before the onset of TdP.[academic.oup.com]

  • Hypokalemia

    […] disease/acute myocardial ischemia Aggressive therapy for hyperglycemia, such as with diabetic ketoacidosis Digitalis therapy Treatment with class III antiarrhythmic drugs (eg, dofetilide[emedicine.medscape.com] Ventricular arrhythmias such as premature ventricular contractions, torsades de pointes, ventricular tachycardia and ventricular fibrillation can also occur [ 8 ] .[patient.info] Ventricular arrhythmias such as premature ventricular contractions, torsades de pointes, ventricular tachycardia and ventricular fibrillation can also occur [ 8 ].[patient.info]

  • Torsade-De-Pointes Syndrome with Short Coupling Interval

    "Dofetilide, a new class III antiarrhythmic agent". Pharmacotherapy . 20 (7): 776–86. doi : 10.1592/phco.20.9.776.35208 . PMID 10907968 .[en.wikipedia.org] The arrhythmia was characterised by short-coupled premature ventricular contractions (PVCs), which were resistant to isoproterenol, and ultimately treated with catheter ablation[touchcardio.com] NSVT: non-sustained ventricular tachycardia. PVC: premature ventricular contraction.[innovationsincrm.com]

  • Cocaine Abuse

    However, we know of no reports concerning management of intentional overdose of dofetilide that have been published.[ncbi.nlm.nih.gov] We report the case of a 33-year-old man who was treated for ingestion of approximately 5 mg of dofetilide as a suicide attempt.[ncbi.nlm.nih.gov] Dofetilide, a class III antiarrhythmic agent, is prescribed for conversion to and maintenance of normal sinus rhythm in patients with persistent atrial fibrillation or atrial[ncbi.nlm.nih.gov]

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