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139 Possible Causes for Down Syndrome, Hemoglobin Decreased, Pica

  • Celiac Disease

    Down syndrome and celiac disease. J Pediatr Gastroent Nutr 21:443-445, 1995. George EK at al. High frequency of celiac disease in Down syndrome. J Peds 128:555-557.[] There is a progressive decrease in the titer of celiac related antibodies.[] Genetic syndromes such as Turner and Down syndromes are associated with an increased risk for celiac disease.[]

  • Anemia

    syndrome Chronic obstructive pulmonary disease Figure 2 Evaluation of normocytic anemia.[] It is defined by abnormally low hemoglobin concentration or decreased red blood cells. Several classification systems exist.[] This behavior is called " pica " (pronounced pie-kuh). Pica often occurs in children who are low in iron and can cause constipation.[]

  • Paroxysmal Nocturnal Hemoglobinuria

    Muscular Dystrophy Treatment Study Efficacy, Safety and Tolerability of RO5186582 in Adults and Adolescents with Down Syndrome Expressive Language Sampling as an Outcome[] Blood complete picture showed decreased hemoglobin and reticulocytosis upto 30%.[] Together, these results argue that the decline in hemoglobin A1c was due to decreased RBC survival secondary to PNH.[]

  • Childhood Celiac Disease

    One child had Down syndrome, and one child had Hashimoto’s thyroiditis with hypothyroidism.[] Abstract Persistent pica may be either a cause or a result of iron deficiency.[] syndrome Turner syndrome Williams syndrome A relative with celiac disease[]

  • Hookworm Infection

    Down's syndrome.[] […] infection and morbidity among schoolchildren and improved hemoglobin concentration.[] The symptoms, as first observed among the negroes, were pain in the stomach, capricious appetite, pica (or dirt-eating), obstinate constipation followed by diarrhoea, palpitations[]

  • Iron Deficiency

    (an irresistible urge to move the legs when sitting or lying down).[] The levels of WBC count were found to decrease in accordance with the decrease in hemoglobin level (Pearson's coefficient: 0.178, P Figure 1 ).[] […] here is related to a 5-year-old girl referred with an abdominal mass and anemia, diagnosed with Rapunzel syndrome and developing trichobezoar due to iron deficiency and pica[]

  • Plummer-Vinson Syndrome

    ダウン Down's syndrome ダウン症候群 JohnLangdon Haydon Down (1828-1896) British doctor Dressler ドレスラー Dressler syndrome ドレスラー症候群 Drummond ドラモンド Drummond sign ドラモンド徴候;口腔吹音 Duane デュアン[] Investigations Complete blood cell (CBC) counts: decreased values of hemoglobin, hematocrit, mean corpuscular volume Peripheral blood smears: hypochromic microcytic anemia[] Pagophagia or pica for ice is often very specific for iron deficieny and can be seen before anemia occurs when iron stores are low.[]

  • Toxoplasmosis

    Recently, it has been suggested that Down syndrome may be caused by congenital T. gondii infection [182], Table 2.[] ; AU Abnormal Fetal Ultrasound; H Headache; NS Night Sweats; TRI trimester; Risk Factors: M Raw/Undercooked Meat; C Significant Cat Exposure; RM Raw Milk; G Gardening; P Pica[] Yamakawa R, Yamashita Y, Yano A, Morita J, Kato H (1996) Congenital toxoplasmosis complicated by central diabetes insipidus in an infant with Down syndrome.[]

  • Congenital Dyserythropoietic Anemia

    syndrome, although in Down syndrome a bone marrow aspirate is not usually required because the blood smear is so striking.[] His seminal contributions to the medical literature have included the first description of the relationship of pica to iron-deficiency anemia (Arch.[] These genes are usually passed down from one or both parents.[]

  • Aplastic Anemia

    Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and[] Patients with decreased serum ferritin (including those without chelation) experienced an increase in hemoglobin, hepatic T2*, cardiac T2*, and LVEF.[] Swollen or sore tongue Cracks or ulcers at the corners of the mouth Difficulty in swallowing Craving to eat unusual non-food substances such as ice or dirt (also known as "pica[]

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