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139 Possible Causes for Down Syndrome, Hemoglobin Decreased, Pica

  • Celiac Disease

    Down syndrome and celiac disease. J Pediatr Gastroent Nutr 21:443-445, 1995. George EK at al. High frequency of celiac disease in Down syndrome. J Peds 128:555-557.[ds-health.com] There is a progressive decrease in the titer of celiac related antibodies.[dx.doi.org] Genetic syndromes such as Turner and Down syndromes are associated with an increased risk for celiac disease.[ncbi.nlm.nih.gov]

  • Anemia

    syndrome Chronic obstructive pulmonary disease Figure 2 Evaluation of normocytic anemia.[dx.doi.org] It is defined by abnormally low hemoglobin concentration or decreased red blood cells. Several classification systems exist.[ncbi.nlm.nih.gov] This behavior is called " pica " (pronounced pie-kuh). Pica often occurs in children who are low in iron and can cause constipation.[healthychildren.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    Muscular Dystrophy Treatment Study Efficacy, Safety and Tolerability of RO5186582 in Adults and Adolescents with Down Syndrome Expressive Language Sampling as an Outcome[rush.edu] Blood complete picture showed decreased hemoglobin and reticulocytosis upto 30%.[ncbi.nlm.nih.gov] Together, these results argue that the decline in hemoglobin A1c was due to decreased RBC survival secondary to PNH.[ncbi.nlm.nih.gov]

  • Childhood Celiac Disease

    One child had Down syndrome, and one child had Hashimoto’s thyroiditis with hypothyroidism.[bmcgastroenterol.biomedcentral.com] Abstract Persistent pica may be either a cause or a result of iron deficiency.[hero.epa.gov] syndrome Turner syndrome Williams syndrome A relative with celiac disease[gikids.org]

  • Hookworm Infection

    Down's syndrome.[square.umin.ac.jp] […] infection and morbidity among schoolchildren and improved hemoglobin concentration.[emedicine.medscape.com] The symptoms, as first observed among the negroes, were pain in the stomach, capricious appetite, pica (or dirt-eating), obstinate constipation followed by diarrhoea, palpitations[en.wikisource.org]

  • Iron Deficiency

    (an irresistible urge to move the legs when sitting or lying down).[merckmanuals.com] The levels of WBC count were found to decrease in accordance with the decrease in hemoglobin level (Pearson's coefficient: 0.178, P Figure 1 ).[bloodjournal.org] […] here is related to a 5-year-old girl referred with an abdominal mass and anemia, diagnosed with Rapunzel syndrome and developing trichobezoar due to iron deficiency and pica[ncbi.nlm.nih.gov]

  • Plummer-Vinson Syndrome

    ダウン Down's syndrome ダウン症候群 JohnLangdon Haydon Down (1828-1896) British doctor Dressler ドレスラー Dressler syndrome ドレスラー症候群 Drummond ドラモンド Drummond sign ドラモンド徴候;口腔吹音 Duane デュアン[jams.med.or.jp] Investigations Complete blood cell (CBC) counts: decreased values of hemoglobin, hematocrit, mean corpuscular volume Peripheral blood smears: hypochromic microcytic anemia[slideshare.net] Pagophagia or pica for ice is often very specific for iron deficieny and can be seen before anemia occurs when iron stores are low.[stanfordmedicine25.stanford.edu]

  • Toxoplasmosis

    Recently, it has been suggested that Down syndrome may be caused by congenital T. gondii infection [182], Table 2.[doi.org] ; AU Abnormal Fetal Ultrasound; H Headache; NS Night Sweats; TRI trimester; Risk Factors: M Raw/Undercooked Meat; C Significant Cat Exposure; RM Raw Milk; G Gardening; P Pica[ncbi.nlm.nih.gov] Yamakawa R, Yamashita Y, Yano A, Morita J, Kato H (1996) Congenital toxoplasmosis complicated by central diabetes insipidus in an infant with Down syndrome.[doi.org]

  • Congenital Dyserythropoietic Anemia

    syndrome, although in Down syndrome a bone marrow aspirate is not usually required because the blood smear is so striking.[oncologynurseadvisor.com] His seminal contributions to the medical literature have included the first description of the relationship of pica to iron-deficiency anemia (Arch.[books.google.com] These genes are usually passed down from one or both parents.[webmd.com]

  • Aplastic Anemia

    Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and[books.google.de] Patients with decreased serum ferritin (including those without chelation) experienced an increase in hemoglobin, hepatic T2*, cardiac T2*, and LVEF.[ncbi.nlm.nih.gov] Swollen or sore tongue Cracks or ulcers at the corners of the mouth Difficulty in swallowing Craving to eat unusual non-food substances such as ice or dirt (also known as "pica[labtestsonline.org]

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