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11 Possible Causes for Down Syndrome, Mean Corpuscular Hemoglobin Concentration Decreased, Pica

  • Celiac Disease

    Down syndrome and celiac disease. J Pediatr Gastroent Nutr 21:443-445, 1995. George EK at al. High frequency of celiac disease in Down syndrome. J Peds 128:555-557.[ds-health.com] syndrome, Turner syndrome, Williams syndrome, selective immunoglobulin (Ig)A deficiency and first degree relatives of individuals with celiac disease.[ncbi.nlm.nih.gov] Genetic syndromes such as Turner and Down syndromes are associated with an increased risk for celiac disease.[ncbi.nlm.nih.gov]

  • Hookworm Infection

    Down's syndrome.[square.umin.ac.jp] The symptoms, as first observed among the negroes, were pain in the stomach, capricious appetite, pica (or dirt-eating), obstinate constipation followed by diarrhoea, palpitations[en.wikisource.org] Some patients may have pica and ingest dirt, which puts them at further risk for infection and Wakana syndrome, characterized by and pharyngeal itching, hoarseness, nausea[symptoma.com]

  • Iron Deficiency

    (an irresistible urge to move the legs when sitting or lying down).[merckmanuals.com] […] here is related to a 5-year-old girl referred with an abdominal mass and anemia, diagnosed with Rapunzel syndrome and developing trichobezoar due to iron deficiency and pica[ncbi.nlm.nih.gov] Automated hematology analyzers detect decreases in the mean corpuscular volume and, in some instruments, increases in the proportion of hypochromic cells.[cancertherapyadvisor.com]

  • Plummer-Vinson Syndrome

    ダウン Down's syndrome ダウン症候群 JohnLangdon Haydon Down (1828-1896) British doctor Dressler ドレスラー Dressler syndrome ドレスラー症候群 Drummond ドラモンド Drummond sign ドラモンド徴候;口腔吹音 Duane デュアン[jams.med.or.jp] Pagophagia or pica for ice is often very specific for iron deficieny and can be seen before anemia occurs when iron stores are low.[stanfordmedicine25.stanford.edu] […] it's a web so food can go down? just dysphagia?(difficulty swallowing) thanks in advance.[prep4usmle.com]

  • Thalassemia Minor

    ’s syndrome and chromosomal unbalanced rearrangements), cerebrovascular disease, and infectious causes (mainly meningitis; tables 5 – 9 ).[ncbi.nlm.nih.gov] FM was associated with female sex and history of pica in IDA patients, and not associated with serum hemoglobin and selected iron parameters.[ncbi.nlm.nih.gov] ( Decreased to normal (8 - 13 g/dL) Mean corpuscular volume (MCV) Slight to no decrease Marked decrease Marked decrease Marked decrease May be slightly decreased Mean corpuscular[labce.com]

  • Constitutional Megaloblastic Anemia due to Folate Metabolism Disorder

    syndrome, Familial platelet syndrome with predisposition to acute myelogenous leukemia, Inherited acute myeloid leukemia, Leukemia, acute lymphoblastic, Non-Hodgkin lymphoma[bbrauncegat.com] Clinical FindingsMild iron deficiency Usually asymptomatic Severe iron deficiency Pallor, fatigue,irritabilily, delayed motor development, concentration defects A history of pica[docslide.net] (MCV, 100 fL ) and mean corpuscular hemoglobin (MCH) Normal mean corpuscular hemoglobin concentration (MCHC, 32–36 g/dL) Decreased reticulocyte count due to destruction of[en.wikipedia.org]

  • Red Blood Cell Disorder

    syndrome and Fanconi anemia All forms of cancer that can spread within the body (malignant), including leukemia, are thought to be due to genetic abnormalities (mutations[medbroadcast.com] Craving for Ice (pica) 23 24 Lab findings in iron deff anemia. Decreased MCV. Decreased serum iron and iron saturation. Decreased serum ferritin.[slideplayer.com] […] fine pin-point red skin rash) caused by too few platelets Blood blisters in the mouth (caused by too few platelets or clotting problems) Pallor (pale skin) caused by anemia Pica[merckmanuals.com]

  • Aplastic Anemia

    Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and[books.google.de] Swollen or sore tongue Cracks or ulcers at the corners of the mouth Difficulty in swallowing Craving to eat unusual non-food substances such as ice or dirt (also known as "pica[labtestsonline.org] […] from parent to child, include: Fanconi anemia Diamond–Blackfan anemia Shwachman–Diamond syndrome Dyskeratosis congenita Fatigue is the most common symptom of anemia.[everydayhealth.com]

  • Anemia due to Vitamin B6 Deficiency

    Pyridoxine-related metabolite concentrations in normal and Down syndrome amniotic fluid. Fetal Diagn Ther. 2008. 23(4):254-7. [Medline]. [Full Text].[emedicine.medscape.com] Palpitations and rapid heart rate Headache Tinnitus - perception of a noise in one or both ears that may be like ringing Taste sense alterations and soreness of the tongue Pica[news-medical.net] Mean Corpuscular Hemoglobin Concentration (MCHC) The average hemoglobin concentration per unit volume (100 ml) of packed red cells is indicated by MCHC.[drkaslow.com]

  • Hexokinase Deficiency

    […] translocator; Ap5A, diadenosine pentaphosphate; ATP-ds, ATP-detecting system; CAT, carboxyatractyloside; db-cAMP, dibutyryl-cAMP; DS, Down's syndrome; DS-HSF, human skin[biochemj.org] […] menstruation (29%) Increased Requirements Pregnancy (6%) Decreased Intake Inadequate diet (19%) Decreased absorption Achlorhydria (41%) Gastric surgery (10%) Celiac disease (6%) Pica[web.archive.org] Cannot synthesize the enzyme phosphorylase (due to a gene mutation) Inability to break down muscle glycogen Prevents lactate production (blood lactate levels do not rise during[quizlet.com]

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