Spinocerebellar Ataxia Type 5
The phenotype is characterized by a purely cerebellar syndrome with a downbeat nystagmus occurring prior to the development of other features.[ncbi.nlm.nih.gov]
Two of the six demonstrated downbeat nystagmus in the primary position on ophthalmoscopy, and one of these and one other displayed upwards gaze evoked nystagmus on upgaze.[jnnp.bmj.com]
Arnold Chiari Malformation
The Arnold-Chiari malfomation is typically associated with downbeat nystagmus.[ncbi.nlm.nih.gov]
Differential Diagnosis of downbeating nystagmus Other causes of constant downbeating nystagmus that should generally be considered are migraine, paraneoplastic cerebellar[dizziness-and-balance.com]
Eye movement recordings in two patients with Arnold-Chiari malfomation type 1 showed, in addition to downbeat and gaze evoked nystagmus, intermittent nystagmus of skew.[ncbi.nlm.nih.gov]
Nystagmus
Downbeating and rightbeating nystagmus Downbeating nystagmus means that the eyes drift upward, and "beat" or jump downward. Examples are shown above.[dizziness-and-balance.com]
Confirmed physician diagnosis of LEMS, CMS or downbeat nystagmus. Completion of anti-cancer treatment at least 3 months (90 days) before treatment.[clinicaltrials.gov]
The authors describe two patients suffering from demyelinating central nervous system disease who developed intense vertigo and downbeat nystagmus upon tilting their heads[ncbi.nlm.nih.gov]
Central Positional Vertigo
Downbeat nystagmus is the most common form of central vestibular nystagmus and results from defective vertical gaze holding that allows for a pathologic upward drift of the[aao.org]
The actual pathophysiology causing the downbeating nystagmus is not well understood at this point, but it is thought that the downbeating nystagmus results from an imbalance[mhmedical.com]
[…] all dealt with elsewhere except for downbeating nystagmus on lateral gaze.[dizziness-and-balance.com]
Brain Stem Disorder
nystagmus and oculomyoclonus (medullary involvement) See Clinical Presentation for more detail.[emedicine.medscape.com]
Sensory loss in the face (involvement of the trigeminal nucleus) Dysphagia and/or dysphonia from lower cranial nerve involvement (commonly IX and X) Long tract signs Ataxia Downbeating[emedicine.medscape.com]
Spinocerebellar Ataxia Type 6
We report two siblings with spinocerebellar ataxia type 6 (SCA 6), both showing downbeat nystagmus (DBN) as a predominant clinical feature.[ncbi.nlm.nih.gov]
In analysis of CAG repeat length in patients with different types of nystagmus, CAG repeat length was the longest when both upbeat and downbeat nystagmus existed (P 0.01).[ncbi.nlm.nih.gov]
Abstract To investigate the frequency of positioning nystagmus in degenerative ataxic disorders, we examined downbeat positioning nystagmus (DPN) in 25 patients with spinocerebellar[ncbi.nlm.nih.gov]
Occult Malignancy
Primary position downbeating nystagmus is an uncommon manifestation of an occult malignancy.[ncbi.nlm.nih.gov]
We report a case of primary position downbeating nystagmus due to an occult breast carcinoma in a 57-year-old woman with progressive oscillopsia and truncal ataxia.[ncbi.nlm.nih.gov]
nystagmus.[ncbi.nlm.nih.gov]
Hereditary Nystagmus
Upbeat jerk nystagmus. Upbeat nystagmus is less frequent than downbeat nystagmus.[neuroophthalmology.ca]
Downbeating nystagmus can be elicited by the head-shaking test.[tchain.com]
Downbeat nystagmus is associated with cervicocranial abnormalities, such as Arnold-Chiari malformation or spinal cerebellar degeneration. Monocular nystagmus.[aao.org]
Pineal Gland Neoplasm
ICD.Codes ICD-10-CM (2016) Chapter 2 Section C73-C75 Code C75.3 BILLABLE Billable Code Billable codes are sufficient justification for admission to an acute care hospital when used a principal diagnosis. ICD-10 from 2011 - 2016 C75.3 is a billable ICD code used to specify a diagnosis of malignant neoplasm of pineal gland.[…][icd.codes]
Phencyclidine Intoxication
Abstract Phencyclidine (PCP) is a dissociative anesthetic whose abuse is a growing problem. Historically, its effects have been considered remarkably like those of the schizophrenic state, but in vitro and in vivo neuropharmacologic data are somewhat inconsistent with the dopaminergic hypothesis of schizophrenia. The[…][ncbi.nlm.nih.gov]