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298 Possible Causes for Downturned Corners of the Mouth, H- or V-Shaped Chin Dimple

  • Native American Myopathy

    corners of the mouth, short stature, and marked susceptibility to malignant hyperthermia.[ncbi.nlm.nih.gov] Symptoms in NAM include congenital muscle weakness and contractures, progressive scoliosis, early ventilatory failure, a peculiar facial gestalt with mild ptosis and downturned[ncbi.nlm.nih.gov]

    Missing: H- or V-Shaped Chin Dimple
  • Malignant Hyperthermia - Arthrogryposis - Torticollis

    corners of mouth Downturned corners of the mouth Downturned mouth [ more ] 0002714 Hypotelorism Abnormally close eyes Closely spaced eyes [ more ] 0000601 Long palm 0011302[rarediseases.info.nih.gov] 59 32 frequent (33%) Frequent (79-30%) HP:0000160 26 conductive hearing impairment 59 32 frequent (33%) Frequent (79-30%) HP:0000405 27 downturned corners of mouth 59 32[malacards.org] corners of mouth Abnormality of the foot Generalized hypotonia due to defect at the neuromuscular junction Apneic episodes precipitated by illness, fatigue, stress Diarrhea[mendelian.co]

    Missing: H- or V-Shaped Chin Dimple
  • Russell-Silver Syndrome

    corners of the mouth Fifth finger clinodactyly May have coffee coloured birthmark *Please be aware, not all of the characteristics may be present* Other information about[littlepeopleuk.org] corners of mouth Downturned corners of the mouth Downturned mouth [ more ] 0002714 Failure to thrive in infancy Faltering weight in infancy Weight faltering in infancy [[rarediseases.info.nih.gov] corners of the mouth.[ghr.nlm.nih.gov]

    Missing: H- or V-Shaped Chin Dimple
  • Jacobsen Syndrome

    These include: wide-set eyes with droopy eyelids small and low-set ears a broad nasal bridge downturned corners of the mouth a small lower jaw a thin upper lip skin folds[healthline.com] ), a broad nasal bridge, downturned corners of the mouth, a thin upper lip, and a small lower jaw.[ghr.nlm.nih.gov] These include small and low-set ears, widely set eyes ( hypertelorism ) with droopy eyelids ( ptosis ), skin folds covering the inner corner of the eyes ( epicanthal folds[ghr.nlm.nih.gov]

    Missing: H- or V-Shaped Chin Dimple
  • Disorder of Sex Development - Intellectual Disability Syndrome

    Showing of 31 80%-99% of people have these symptoms Deeply set eye Deep set eye Deep-set eyes Sunken eye [ more ] 0000490 Downturned corners of mouth Downturned corners of[rarediseases.info.nih.gov] corners of mouth 60 33 hallmark (90%) Very frequent (99-80%) HP:0002714 16 hypoplasia of penis 60 33 hallmark (90%) Very frequent (99-80%) HP:0008736 17 spina bifida occulta[malacards.org] […] the mouth Downturned mouth [ more ] 0002714 Genu valgum Knock knees 0002857 Hypogonadism Decreased activity of gonads 0000135 Hypoplasia of penis Underdeveloped penis 0008736[rarediseases.info.nih.gov]

    Missing: H- or V-Shaped Chin Dimple
  • Curry Hall Syndrome

    Facial features included ptosis, hypertelorism, epicanthal folds, cupped simple ears, and wide mouth with downturned corners.[genome.jp] For FSS, they required the following: microstomia, whistling-face appearance (pursed lips), H or V-shaped chin dimpling, prominent nasolabial folds, and major contractures[systematicreviewsjournal.biomedcentral.com] […] or V-shaped chin dimple Computed tomography scan (Give findings, if stated) Published diagnostic term Prominent nasolabial folds Electroencephalography Primary published diagnosis[systematicreviewsjournal.biomedcentral.com]

  • Cornelia De Lange Syndrome

    Clinical description Distinctive facial features include: well-defined curved and confluent eyebrows, long eyelashes, anteverted nares, micrognathia, and downturned corners[orpha.net] corners of the mouth.[aadmd.org] corners of mouth Downturned corners of the mouth Downturned mouth [ more ] 0002714 Gastroesophageal reflux Acid reflux Acid reflux disease Heartburn [ more ] 0002020 Generalized[rarediseases.info.nih.gov]

    Missing: H- or V-Shaped Chin Dimple
  • Monosomy 21q

    corners to the mouth, body asymme-try, and fifth-finger clinodactyly.[documents.tips] And Oral Structures Downturned Corners Of The Mouth Cleft Lip/Or Palate Highly Arched Palate Abdomen Inguinal Hernia Hand And Foot Talipes Equinovarus, Camptodactyly, Long[neo-genetics.com] […] died of pneumonia at age 8 months.SilverRussell syndrome (SRS; OMIM 180860) is characterizedby congenital short stature, preservation of normal head size,triangular face, downturned[documents.tips]

    Missing: H- or V-Shaped Chin Dimple
  • Chromosome 18p Deletion Syndrome

    The proband is a 15-year-old male who has had phenotypes manifested mainly by brachycephaly, broad faces, ptosis, downturned corners of the mouth, tooth abnormalities, broad[academic.oup.com] 0000175 Downturned corners of mouth Downturned corners of the mouth Downturned mouth [ more ] 0002714 Enlarged thorax Wide rib cage 0100625 Epicanthus Eye folds Prominent[rarediseases.info.nih.gov] The phenotypic manifestations were the following: brachycephaly, broad face, ptosis, downturned corners of the mouth, tooth abnormalities, broad neck with a low posterior[academic.oup.com]

    Missing: H- or V-Shaped Chin Dimple
  • Obesity

    She showed normal linear growth and cognition, but mildly dysmorphic facial traits including deeply-set eyes, prominent zygomatic bones, downturned mouth corners and low-set[ncbi.nlm.nih.gov]

    Missing: H- or V-Shaped Chin Dimple

Further symptoms