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13 Possible Causes for Drop Attacks, Hypotension, Severe Recurrent Orthostatic Hypotension

  • Orthostatic Hypotension

    A 71-year-old man, who was diagnosed with familial amyloidosis type I, was admitted for treatment of severe orthostatic hypotension associated with recurrent syncopal attacks[ncbi.nlm.nih.gov] The drop in blood pressure may be sudden (vasovagal orthostatic hypotension), within 3 minutes (classic orthostatic hypotension) or gradual (delayed orthostatic hypotension[en.wikipedia.org] OH is defined specifically as a 20mmHg drop in systolic, and/or a 10mmHg drop in diastolic BP within 3 min of standing.[clinicaltrials.gov]

  • Syncope

    However, a syncopal episode associated with normal sinus rhythm may be due to several disorders such as orthostatic hypotension, vasovagal or carotid sinus reflexes, or even[omicsonline.org] We reported a 75-year-old man who had recurrent syncope attacks secondary to hypotension and reduced plasma norepinephrine (NE) levels.[ncbi.nlm.nih.gov] […] classification chosen here only represents one possibility. 2.1 Vascular syncopes Orthostatic hypotension Stenosis of the cerebral arteries Subclavian-Steal-syndrome (" drop[flexikon.doccheck.com]

  • Micturition Syncope

    Syncope is usually not recurrent; however, recurrent micturition syncope has been reported with bladder neck obstruction, severe chronic orthostatic hypotension, and paroxysmal[ncbi.nlm.nih.gov] To describe a case of severe hypotension and occasional syncope following intermittent catheterisations in a tetraplegic patient.[ncbi.nlm.nih.gov] Differential diagnosis of Blackouts • Syncope • Epilepsy • Psychogenic non-epileptic seizures •Cataplexy  Drop attack • Transient CSF obstruction • Transient ischaemic attack[slideshare.net]

  • Dopamine Beta-Hydroxylase Deficiency

    Abstract A woman was referred with severe orthostatic hypotension at the age of 21.[ncbi.nlm.nih.gov] With a dose of 500 mg twice daily by mouth, blood pressure rose gradually from 100/55 to 145/85 mm Hg, and orthostatic hypotension disappeared.[ncbi.nlm.nih.gov] OH is defined specifically as a 20mmHg drop in systolic, and/or a 10mmHg drop in diastolic BP within 3 min of standing.[allmedx.com]

  • Orthostatic Syncope

    Although symptom recurrence on follow-up was lower in patients with more severe orthostatic hypotension, the clinical significance of this finding needs to be further defined[ncbi.nlm.nih.gov] 2) Orthostatic Hypotension 5-29 % of all causes syncope Aging changes in physiology that predispose to orthostatic hypotension: - decrease in B-adrenergic responsivenss -[unmc.edu] Drop attacks. Dizziness or vertigo without loss of consciousness. Alcohol/drug abuse. Transient ischaemic attacks / stroke. Psychogenic pseudosyncope.[patient.info]

  • Hypotension

    Effects of orthostatic hypotension on cognition in Parkinson disease. Neurology 2017, 88:17-24 Connolly S and others.[dizziness-and-balance.com] Dysautonomia Hypotensive transfusion reaction Orthostatic intolerance Hypotension PubMed Health[en.wikipedia.org] Postprandial hypotension is a sudden drop in blood pressure after a meal.[nhlbi.nih.gov]

  • Pure Autonomic Failure

    First, patients with PAF did not have severe urinary disturbances, which would lessen the risk of recurrent urinary infections, and they also did not have life threatening[jnnp.bmj.com] Emotional stimuli have not previously been reported to cause hypotension in patients with autonomic failure.[ncbi.nlm.nih.gov] The disease progresses very slowly, and usually presents with a picture of lightheadedness and gradual fading to syncope, often resulting in sudden falls or “drop attacks.[njfaint.com]

  • Mesenteric Infarction

    Syncope is usually not recurrent; however, recurrent micturition syncope has been reported with bladder neck obstruction, severe chronic orthostatic hypotension, and paroxysmal[ncbi.nlm.nih.gov] Nonocclusive mesenteric infarction has been reported very rarely during continuous ambulatory peritoneal dialysis, and only in the setting of cardiac dysfunction or prolonged hypotension[ncbi.nlm.nih.gov] Associated predisposing factors were the presence of orthostatic hypoxemia, postural hypotension and extensive atheromatous changes of the abdominal aorta.[ncbi.nlm.nih.gov]

  • Idiopathic Bilateral Vestibulopathy

    Patients most often experience BPPV when lying down, which distinguishes BPPV from orthostatic hypotension. In addition, BPPV may be recurrent.[raleighcapitolent.com] Lightheadedness brought on by getting up quickly from a lying or sitting position is typical of orthostatic hypotension; however, patients with BPPV may also have brief vertigo[touchneurology.com] BPPV can lead to falls or drop-like attacks. BPPV has a 95% or greater successful treatment rate.[hearingreview.com]

  • Microphthalmos

    Syncope is usually not recurrent; however, recurrent micturition syncope has been reported with bladder neck obstruction, severe chronic orthostatic hypotension, and paroxysmal[ncbi.nlm.nih.gov] Physical examination disclosed orthostatic hypotension in 22 of these 25 patients. Therapy was directed at improving orthostasis.[jamanetwork.com] […] typically have a benign self-limited condition, whereas older male patients and female patients of any age typically have significant medical comorbidities and orthostatic hypotension[medlink.com]

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