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13 Possible Causes for Drug-induced Cardiomyopathy, Echocardiogram Abnormal, Pulsus Alternans

  • Congestive Heart Failure

    alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] […] rhythms (arrhythmias or dysrhythmias) and detects problems with the heart muscle Echocardiogram (echo) - a noninvasive test that uses sound waves to produce a study of the[chw.org]

  • Myocardial Infarction

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] Left ventricular focal hypokinesia was seen by echocardiogram or angiography in 5 patients and abnormal coronary anatomy in none.[pediatrics.aappublications.org] Unfortunately, the presence of wall motion abnormalities on the echocardiogram may be the result of an acute MI or previous (old) MI or other myopathic processes, limiting[web.archive.org]

  • Dilated Cardiomyopathy

    Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Pulsus alternans is an infrequent, complex pathophysiologic sign often associated with severe heart failure.[ncbi.nlm.nih.gov] There may be a heart murmur (made by abnormal backward flow through the mitral valve) or other extra heart sounds and the liver is often enlarged.[mottchildren.org]

  • Acute Myocarditis

    Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.[scielo.br] Dallas criteria are used for the histological diagnosis of myocarditis. [1,3] Echocardiography Echocardiogram can roughly locate the site of inflammation.[explainmedicine.com] Surprisingly however, the echocardiogram performed in both patients failed to reveal any regional or global wall motion abnormalities or even diastolic dysfunction and remained[ncbi.nlm.nih.gov]

  • Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] Two-dimensional echocardiograms revealed left ventricular noncompaction, which markedly improved after standard heart failure therapy.[ncbi.nlm.nih.gov]

  • Alcoholic Cardiomyopathy

    Leg elevation promptly reversed the pulsus alternans, and the echocardiographic abnormality.[ncbi.nlm.nih.gov] Models, Animal Ethanol/toxicity Gene Expression Regulation/drug effects Heart Failure/chemically induced Heart Failure/genetics* Heart Failure/pathology Humans Mice Mitochondria[ncbi.nlm.nih.gov] Echocardiogram abnormalities and cardiac catheterization or angiogram to rule out coronary artery blockages, along with a history of alcohol abuse can confirm the diagnosis[en.wikipedia.org]

  • Toxic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Or an echocardiogram may show some abnormalities, such as decreased strength of heart contractions.[drugs.com] Dallas criteria are used for the histological diagnosis of myocarditis. [1,3] Echocardiography Echocardiogram can roughly locate the site of inflammation.[explainmedicine.com]

  • Cardiac Dyskinesia

    Antiarrhythmic drug therapy for atrial fibrillation. Zimetbaum P. Circulation 2012;125:381-9 Cocco G, Chu D: 23. Stress induced cardiomyopathy, a review. Cocco C. Eur.[escardio.org] Pulsus alternans is generally seen in severe heart failure.[textbookofcardiology.org] Pulsus alternans is defined by a beat-to-beat variability of the pulse amplitude.[textbookofcardiology.org]

  • Hypersensitivity Myocarditis

    A prompt diagnosis, immediate withdrawal of the offending drug and immunosuppressant therapy may decrease mortality in drug-induced acute EM [ 1 ].[karger.com] An ECG showed an increase of voltages with the disappearance of repolarization abnormalities.[the-medical-dictionary.com] Anthracycline-induced cardiomyopathy. Postgrad. Med. 2008, 120, 67–72. [ Google Scholar ] [ CrossRef ] [ PubMed ] Taliercio, C.P.; Olney, B.A.; Lie, J.T.[mdpi.com]

  • Hemochromatosis-related Cardiomyopathy

    Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Interventricular dependence is the hallmark of a diagnosis of constrictive pericarditis, and is typically seen on echocardiogram as abnormal septal motion or leftward movement[clinicaladvisor.com] Other lab results such as elevated liver function tests, elevated glucose/HbA1C, and abnormal EKG/echocardiogram findings suggest late manifestations of the disease.[emdocs.net]