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14 Possible Causes for Drug-induced Cardiomyopathy, Heart Murmur, Pulsus Alternans

  • Congestive Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] The possibility of traumatic ventricular septal defect should be considered in all multiple-trauma patients who develop a new heart murmur, even when overt chest-wall injury[ncbi.nlm.nih.gov]

  • Dilated Cardiomyopathy

    Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Pulsus alternans is an infrequent, complex pathophysiologic sign often associated with severe heart failure.[ncbi.nlm.nih.gov] There may also be a fast or slow heart beat and the doctor may hear an abnormal heart sound (heart murmur) through a stethoscope, or a large heart may be visible on an x-[chfed.org.uk]

  • Myocardial Infarction

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] The provider may hear abnormal sounds in your lungs (called crackles), a heart murmur, or other abnormal sounds. You may have a fast or uneven pulse.[nlm.nih.gov] Full text article Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications Full text article Febuxostat for Cerebral[eurheartj.oxfordjournals.org]

  • Alcoholic Cardiomyopathy

    Models, Animal Ethanol/toxicity Gene Expression Regulation/drug effects Heart Failure/chemically induced Heart Failure/genetics* Heart Failure/pathology Humans Mice Mitochondria[ncbi.nlm.nih.gov] Leg elevation promptly reversed the pulsus alternans, and the echocardiographic abnormality.[ncbi.nlm.nih.gov] Chest examination may reveal heart murmur. Due to fluid retention excessive swelling in the lower extremities and other parts of the body takes place.[ic.steadyhealth.com]

  • Toxic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] In infants, symptoms may also include bluish skin, heart murmurs, and a poor appetite.[healthcentral.com] Nearly all patients will have an audible heart murmur.[atsu.edu]

  • Hypersensitivity Myocarditis

    A prompt diagnosis, immediate withdrawal of the offending drug and immunosuppressant therapy may decrease mortality in drug-induced acute EM [ 1 ].[karger.com] Cardiac examination may be significant for a third (S3) or fourth (S4) heart sound.[merckmanuals.com] Anthracycline-induced cardiomyopathy. Postgrad. Med. 2008, 120, 67–72. [ Google Scholar ] [ CrossRef ] [ PubMed ] Taliercio, C.P.; Olney, B.A.; Lie, J.T.[mdpi.com]

  • Acute Myocarditis

    Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.[scielo.br] Transformation of myocarditis and inflammatory cardiomyopathy to idiopathic dilated cardiomyopathy: facts and fiction.[scielo.br]

  • Lymphocytic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] Heart murmurs may indicate the presence of valvular heart disease, either as a cause (e.g. aortic stenosis) or as a result (e.g. mitral regurgitation) of the heart failure[en.wikipedia.org]

  • High Output Heart Failure

    […] an alcoholic cardiomyopathy.[emedicine.medscape.com] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] Here we present a case in which a systolic heart murmur was the first manifestation of high output heart failure due to a VGAM.[ncbi.nlm.nih.gov]

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