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11 Possible Causes for Drug-induced Cardiomyopathy, Malaise, Pulsus Alternans

  • Congestive Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] 53,785 9,322 17.3 247 Lymphadenitis 13,632 1,242 9.1 248 Gangrene 33,786 10,693 31.6 250 Nausea and vomiting 51,833 11,854 22.9 251 Abdominal pain 166,071 26,993 16.3 252 Malaise[web.archive.org]

  • Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] 53,785 9,322 17.3 247 Lymphadenitis 13,632 1,242 9.1 248 Gangrene 33,786 10,693 31.6 250 Nausea and vomiting 51,833 11,854 22.9 251 Abdominal pain 166,071 26,993 16.3 252 Malaise[hcup-us.ahrq.gov]

  • Myocardial Infarction

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] General epigastric (upper middle abdomen) discomfort Sweating Heartburn and/or indigestion Arm pain (more commonly the left arm, but may be either arm) Upper back pain General malaise[medicinenet.com] Patients with typical acute MI usually present with chest pain and may have prodromal symptoms of fatigue, chest discomfort, or malaise in the days preceding the event; alternatively[emedicine.medscape.com]

  • Acute Myocarditis

    Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.[scielo.br] A 43-year-old previously healthy Taiwanese male came to our emergency department due to high fever, chills, general malaise and myalgia for about 4 days.[ncbi.nlm.nih.gov] The clinical presentation starts with a flu-like symptomatology (fatigue, malaise, and constitutional symptoms), followed by dyspnea, palpitations, arrhythmias, and chest[symptoma.com]

  • Hypersensitivity Myocarditis

    A prompt diagnosis, immediate withdrawal of the offending drug and immunosuppressant therapy may decrease mortality in drug-induced acute EM [ 1 ].[karger.com] In retrospect, the presence of signs and symptoms of hypersensitivity (skin rash, fever, eosinophilia, and malaise) and nonspecific cardiac findings (electrocardiographic[ncbi.nlm.nih.gov] Case Report A 63-year-old man presented to the emergency department with a history of flu-like symptoms, fever and malaise followed by respiratory-dependent chest pain.[link.springer.com]

  • Lymphocytic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Malaise, low grade fever and myalgias during last three days. No chest pain.[app.figure1.com] Introduction In late December 2015, a 69-year-old woman presented with general malaise and palpitation lasting a few days.[circheartfailure.ahajournals.org]

  • Toxic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] A month or two later, the symptoms of flu (weakness and malaise) merge with symptoms of heart failure (fatigue during physical activity and shortness of breath).[healthcentral.com] ( palpitations ) Sudden death (in young adults) Fever (usually associated with an infectious process) Myocarditis in children and infants has more nonspecific symptoms: Malaise[medicinenet.com]

  • Dilated Cardiomyopathy

    Pulsus alternans is an infrequent, complex pathophysiologic sign often associated with severe heart failure.[ncbi.nlm.nih.gov] Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] A viral prodrome with malaise, flu-like illness or chest pain from antecedent myocarditis may be present. Atrial fibrillation may develop.[patient.info]

  • Alcoholic Cardiomyopathy

    Models, Animal Ethanol/toxicity Gene Expression Regulation/drug effects Heart Failure/chemically induced Heart Failure/genetics* Heart Failure/pathology Humans Mice Mitochondria[ncbi.nlm.nih.gov] Leg elevation promptly reversed the pulsus alternans, and the echocardiographic abnormality.[ncbi.nlm.nih.gov] Medical detox will often use medications to manage some of the more difficult withdrawal symptoms like nausea and vomiting, headaches, insomnia, fatigue, and general malaise[sdtreatmentcenter.com]

  • Hemochromatosis-related Cardiomyopathy

    Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Patients are often asymptomatic, but early clinical features can include fatigue, malaise, arthralgia, and decreased libido.[unboundmedicine.com] Patients often seek help because of tiredness, abdominal discomfort, joint pains, and general malaise experienced over a prolonged period of time.[dermnetnz.org]