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332 Possible Causes for Drug-induced Cardiomyopathy, Non Specific ST-T Changes, Pulsus Alternans

  • Dilated Cardiomyopathy

    Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Pulsus alternans is an infrequent, complex pathophysiologic sign often associated with severe heart failure.[ncbi.nlm.nih.gov] Electrocardiogram revealed sinus tachycardia and non-specific ST-T changes in the lateral leads.[doi.org]

  • Acute Myocarditis

    Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.[scielo.br] (i) The ECG The ECG most commonly demonstrates a sinus tachycardia with or without non-specific ST segment and T wave changes.[rcemlearning.co.uk] Transformation of myocarditis and inflammatory cardiomyopathy to idiopathic dilated cardiomyopathy: facts and fiction.[scielo.br]

  • Toxic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] The most common abnormality seen in myocarditis is sinus tachycardia with non-specific ST segment and T wave changes.[lifeinthefastlane.com] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • Lymphocytic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] On ICU admission, a 12-lead electrocardiogram (ECG) detected sinus tachycardia of 100/min and non-specific ST-T wave changes without any significant evidence of acute myocardial[eurjmedres.biomedcentral.com] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • Alcoholic Cardiomyopathy

    Models, Animal Ethanol/toxicity Gene Expression Regulation/drug effects Heart Failure/chemically induced Heart Failure/genetics* Heart Failure/pathology Humans Mice Mitochondria[ncbi.nlm.nih.gov] Leg elevation promptly reversed the pulsus alternans, and the echocardiographic abnormality.[ncbi.nlm.nih.gov] Gov't MeSH terms Acetaldehyde/toxicity Aldehyde Dehydrogenase, Mitochondrial/genetics Animals Cardiomyopathy, Alcoholic/genetics* Cardiomyopathy, Alcoholic/pathology Disease[ncbi.nlm.nih.gov]

  • Hypersensitivity Myocarditis

    A prompt diagnosis, immediate withdrawal of the offending drug and immunosuppressant therapy may decrease mortality in drug-induced acute EM [ 1 ].[karger.com] Anthracycline-induced cardiomyopathy. Postgrad. Med. 2008, 120, 67–72. [ Google Scholar ] [ CrossRef ] [ PubMed ] Taliercio, C.P.; Olney, B.A.; Lie, J.T.[mdpi.com] In subacute and chronic EM, intracardiac thrombi, endomyocardial fibrosis and restrictive cardiomyopathy can be found.[karger.com]

  • Hemochromatosis-related Cardiomyopathy

    Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Sinus tachycardia is frequently present, and non-specific ST-segment or T-wave changes as well as changes in P-wave morphology may well be present.[textbookofcardiology.org] Medications-induced cardiomyopathy – the most pathogenic are chemotherapeutic agents such as anthracyclines, cyclophosphamide, and trastuzumab.[escardio.org]

  • Acute Amphetamine Intoxication

    Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test[…][books.google.de]

    Missing: Pulsus Alternans
  • Cardiomyopathy

    Cardiomyopathy is disease in which the heart muscle becomes weakened, stretched, or has another structural problem. It often occurs when the heart cannot pump or function well. Most people with cardiomyopathy have heart failure. There are many types of cardiomyopathy, with different causes. Some of the more[…][nlm.nih.gov]

    Missing: Drug-induced Cardiomyopathy
  • Ischemic Cardiomyopathy

    Because of the shortage of donor hearts, 16 (33%) of 48 patients with ischemic cardiomyopathy died awaiting transplantation. Determining factors that predict effective coronary revascularization and identifying patients who may benefit from revascularization is crucial. From 1984 to 1990, 207 ischemic cardiomyopathy[…][ncbi.nlm.nih.gov]

    Missing: Drug-induced Cardiomyopathy