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14 Possible Causes for Drug-induced Cardiomyopathy, Pulsus Alternans

  • Congestive Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] […] defects Cardiac arrhythmias Chronic lung disease Pulmonary embolism Drug-induced heart failure Excessive sodium intake Hemorrhage Anemia Diabetes Diagnosing Congestive Heart[wexnermedical.osu.edu]

  • Heart Failure

    alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] Pulsus alternans is usually associated with an S 3 gallop, signifies advanced myocardial disease, and often disappears with treatment of heart failure.[emedicine.medscape.com]

  • Myocardial Infarction

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] Full text article Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications Full text article Febuxostat for Cerebral[eurheartj.oxfordjournals.org]

  • Dilated Cardiomyopathy

    Pulsus alternans is an infrequent, complex pathophysiologic sign often associated with severe heart failure.[ncbi.nlm.nih.gov] Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] cardiomyopathy Tachycardia-induced cardiomyopathy (TIC) is caused by sustained rapid ventricular rates and is one of the well-known forms of reversible myocardial diseases[ncbi.nlm.nih.gov]

  • Alcoholic Cardiomyopathy

    Models, Animal Ethanol/toxicity Gene Expression Regulation/drug effects Heart Failure/chemically induced Heart Failure/genetics* Heart Failure/pathology Humans Mice Mitochondria[ncbi.nlm.nih.gov] Leg elevation promptly reversed the pulsus alternans, and the echocardiographic abnormality.[ncbi.nlm.nih.gov] Gov't MeSH terms Acetaldehyde/toxicity Aldehyde Dehydrogenase, Mitochondrial/genetics Animals Cardiomyopathy, Alcoholic/genetics* Cardiomyopathy, Alcoholic/pathology Disease[ncbi.nlm.nih.gov]

  • Acute Myocarditis

    Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.[scielo.br] Transformation of myocarditis and inflammatory cardiomyopathy to idiopathic dilated cardiomyopathy: facts and fiction.[scielo.br]

  • Toxic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • Hypersensitivity Myocarditis

    A prompt diagnosis, immediate withdrawal of the offending drug and immunosuppressant therapy may decrease mortality in drug-induced acute EM [ 1 ].[karger.com] Anthracycline-induced cardiomyopathy. Postgrad. Med. 2008, 120, 67–72. [ Google Scholar ] [ CrossRef ] [ PubMed ] Taliercio, C.P.; Olney, B.A.; Lie, J.T.[mdpi.com] In subacute and chronic EM, intracardiac thrombi, endomyocardial fibrosis and restrictive cardiomyopathy can be found.[karger.com]

  • Lymphocytic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • Hemochromatosis-related Cardiomyopathy

    Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Medications-induced cardiomyopathy – the most pathogenic are chemotherapeutic agents such as anthracyclines, cyclophosphamide, and trastuzumab.[escardio.org] Tachycardia-induced cardiomyopathy – persistent tachycardia, particularly uncontrolled atrial fibrillation, atrio-ventricular nodal reentry, and preexcitation syndromes with[escardio.org]

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