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11 Possible Causes for Drug-induced Cardiomyopathy, Pulsus Alternans, S3 Gallop

  • Congestive Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] […] criteria: · Paroxysmal nocturnal dyspnea · Neck vein distention · Rales · Radiographic cardiomegaly (increasing heart size on chest radiography) · Acute pulmonary edema · S3[medicalcriteria.com]

  • Myocardial Infarction

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] Heart sounds are auscultated for S3 or S4 gallops or new heart murmurs. Patient care and other activities should be organized to allow for periods on uninterrupted rest.[medical-dictionary.thefreedictionary.com] Full text article Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications Full text article Febuxostat for Cerebral[eurheartj.oxfordjournals.org]

  • Dilated Cardiomyopathy

    Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Pulsus alternans is an infrequent, complex pathophysiologic sign often associated with severe heart failure.[ncbi.nlm.nih.gov] He was tachycardic, with an S3/S4 gallop rhythm. There were moist rales in the lung fields and chest wall retraction. The abdominal exam revealed hepatomegaly.[revportcardiol.org]

  • Acute Myocarditis

    Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.[scielo.br] The physical examination is perhaps even more important, which can reveal tachycardia, cardiac murmurs (soft S1 sound, S3 or S4 gallop, as well as sounds pointing toward insufficiency[symptoma.com] Transformation of myocarditis and inflammatory cardiomyopathy to idiopathic dilated cardiomyopathy: facts and fiction.[scielo.br]

  • Toxic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Cardiogenic shock in fulminant cases Auscultation findings Brief systolic murmurs Heart failure S3 (and S4) gallops Pericarditis pericardial friction rub The clinical manifestation[amboss.com] A S3 gallop indicates left-sided congestive heart failure.[atsu.edu]

  • Alcoholic Cardiomyopathy

    Models, Animal Ethanol/toxicity Gene Expression Regulation/drug effects Heart Failure/chemically induced Heart Failure/genetics* Heart Failure/pathology Humans Mice Mitochondria[ncbi.nlm.nih.gov] Leg elevation promptly reversed the pulsus alternans, and the echocardiographic abnormality.[ncbi.nlm.nih.gov] Gov't MeSH terms Acetaldehyde/toxicity Aldehyde Dehydrogenase, Mitochondrial/genetics Animals Cardiomyopathy, Alcoholic/genetics* Cardiomyopathy, Alcoholic/pathology Disease[ncbi.nlm.nih.gov]

  • Hypersensitivity Myocarditis

    A prompt diagnosis, immediate withdrawal of the offending drug and immunosuppressant therapy may decrease mortality in drug-induced acute EM [ 1 ].[karger.com] Anthracycline-induced cardiomyopathy. Postgrad. Med. 2008, 120, 67–72. [ Google Scholar ] [ CrossRef ] [ PubMed ] Taliercio, C.P.; Olney, B.A.; Lie, J.T.[mdpi.com] In subacute and chronic EM, intracardiac thrombi, endomyocardial fibrosis and restrictive cardiomyopathy can be found.[karger.com]

  • Heart Failure

    alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] […] criteria: · Paroxysmal nocturnal dyspnea · Neck vein distention · Rales · Radiographic cardiomegaly (increasing heart size on chest radiography) · Acute pulmonary edema · S3[web.archive.org]

  • High Output Heart Failure

    alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] […] an alcoholic cardiomyopathy.[emedicine.medscape.com] Physical examination reveals an S3 gallop, hepatomegaly, warm skin and a continuous bruit over the right upper thigh.[medbullets.com]

  • Cardiac Dyskinesia

    Pulsus alternans is generally seen in severe heart failure.[textbookofcardiology.org] Antiarrhythmic drug therapy for atrial fibrillation. Zimetbaum P. Circulation 2012;125:381-9 Cocco G, Chu D: 23. Stress induced cardiomyopathy, a review. Cocco C. Eur.[escardio.org] The combined presence of S3 and S4 is a quadruple gallop. At rapid heart rates, S3 and S4 may merge to produce a summation gallop.[textbookofcardiology.org]