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13 Possible Causes for Drug-induced Cardiomyopathy, Pulsus Alternans, Systolic Murmur

  • Congestive Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] […] and diastolic murmurs and radiographic cardiomegaly.[nichiju.lin.gr.jp]

  • Myocardial Infarction

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] On day 2, however, the patient's vital signs deteriorated to a state of shock and systolic murmur appeared at the apical region.[ncbi.nlm.nih.gov] Third and fourth heart sound, systolic murmur if mitral regurgitation or ventricular septal defect develops, pericardial rub.[patient.info]

  • Dilated Cardiomyopathy

    Pulsus alternans is an infrequent, complex pathophysiologic sign often associated with severe heart failure.[ncbi.nlm.nih.gov] Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] cardiomyopathy Tachycardia-induced cardiomyopathy (TIC) is caused by sustained rapid ventricular rates and is one of the well-known forms of reversible myocardial diseases[ncbi.nlm.nih.gov]

  • Alcoholic Cardiomyopathy

    Models, Animal Ethanol/toxicity Gene Expression Regulation/drug effects Heart Failure/chemically induced Heart Failure/genetics* Heart Failure/pathology Humans Mice Mitochondria[ncbi.nlm.nih.gov] Leg elevation promptly reversed the pulsus alternans, and the echocardiographic abnormality.[ncbi.nlm.nih.gov] Systolic cardiac murmurs could be heard on mitral valve area, III/6 and conducted to left axilla.[jtd.amegroups.com]

  • Hypersensitivity Myocarditis

    A prompt diagnosis, immediate withdrawal of the offending drug and immunosuppressant therapy may decrease mortality in drug-induced acute EM [ 1 ].[karger.com] She had a systolic murmur at the apex. Her chest auscultation was normal. Abdominal examination was unremarkable.[pmj.bmj.com] Systolic murmurs of mitral regurgitation and tricuspid regurgitation may be present in patients with ventricular enlargement.[merckmanuals.com]

  • Toxic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Cardiogenic shock in fulminant cases Auscultation findings Brief systolic murmurs Heart failure S3 (and S4) gallops Pericarditis pericardial friction rub The clinical manifestation[amboss.com] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • Acute Myocarditis

    Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.[scielo.br] Transformation of myocarditis and inflammatory cardiomyopathy to idiopathic dilated cardiomyopathy: facts and fiction.[scielo.br]

  • Lymphocytic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • Heart Failure

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] A physical examination revealed a systolic murmur, which was best audible in the right parasternal side, ascites, and hepatomegaly.[ncbi.nlm.nih.gov]

  • High Output Heart Failure

    […] an alcoholic cardiomyopathy.[emedicine.medscape.com] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info] Here we present a case in which a systolic heart murmur was the first manifestation of high output heart failure due to a VGAM.[elsevier.es]

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