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11 Possible Causes for Drug-induced Hemolytic Anemia, Glycogen Storage Disease Type 1, Polychromasia in Peripheral Blood Smear

  • Autoimmune Hemolytic Anemia

    […] disease, chronic Cold antibody hemolytic anemia Cold autoimmune hemolytic anemia Drug induced autoimmune hemolytic anemia Drug induced hemolytic anemia, immune complex type[] Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[] -Red cell morphology on review of the peripheral blood smear may demonstrate microspherocytes and polychromasia which are suggestive of a reactive reticulocytosis.[]

  • Paroxysmal Cold Hemoglobinuria

    An initial impression of intravascular hemolysis (autoimmune versus drug-induced hemolytic anemia) with uremic gastritis/gastropathy was made.[] storage disease グリコーゲン蓄積症,糖原病(0a型) glycogen storage disease (type 0a) グリコーゲン蓄積症,糖原病(0b型) glycogen storage disease (type 0b) グリコーゲン蓄積症,糖原病(I型) glycogen storage disease (type[] Tests include complete blood count (CBC) and peripheral smear.[]

  • Hemolytic Anemia due to a Disorder of Glycolytic Enzymes

    Drug induced hemolytic anemias associated with an unstable hemoglobin may present with clinical laboratory features similar to G-6-PD deficiency, including the hallmark “hemighost[] "Glycogen storage disease type I: diagnosis, management, clinical course and outcome.Results of the European study on glycogen storage disease type I".[] blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[]

  • Anemia due to Glutathione Metabolism Disorder

    Differential diagnosis Drug-induced hemolytic anemia due to G-6-PD deficiency is similar in its clinical features and in certain laboratory features to drug-induced hemolytic[] […] deficiency GK Glycogen storage disease of heart (lethal) PRKAG2 Glycogen storage disease type 0 muscle GYS1 Glycogen storage disease type 0 GYS2 Glycogen storage disease[] The peripheral blood smear post-splenectomy often shows crenated or spiculated spherocytes and marked polychromasia.[]

  • Autosomal Dominant Aplasia and Myelodysplasia

    […] are rare) Hemolytic anemia Slide 24 An approach to hemolytic anemia ImmuneNon-immune CongenitalAcquired Defects of: RBC membrane/ skeleton (eg.[] Chou JY, Mansfield BC: Molecular genetics of type 1 glycogen storage disease . TEM 1999, 10 :104–113. Google Scholar 9.[] Hgb 4.6 g/dL MCV 55 Retic 2.1% *Further history reveals he drinks 64 ounces of cows milk per day Plt 520 (H) TIBC 510 (H) Ferritin 3 (H) Case 1 Peripheral Blood Smear Normal[]

  • Chronic Acquired Pure Red Cell Aplasia

    […] autoimmune hemolytic anemia Dysembryoplastic neuroepithelial tumor Dyskeratosis congenita East Texas bleeding disorder Embryonal carcinoma Embryonal carcinoma of the central[] storage disease グリコーゲン蓄積症,糖原病(0a型) glycogen storage disease (type 0a) グリコーゲン蓄積症,糖原病(0b型) glycogen storage disease (type 0b) グリコーゲン蓄積症,糖原病(I型) glycogen storage disease (type[] blood smear showed anisocytosis, poikilocytosis, polychromasia and leukocytosis.[]

  • Idiopathic Neonatal Atrial Flutter

    Anemias in those disorders are usually hypochromic and microcytic. Glucose-6-phosphate dehydrogenase deficiency is usually drug-induced.[] Arad M et al . (2002) Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy . J Clin Invest 109 : 357–362 45.[] Rarely, suspected metabolic diseases (isolated myocardial carnitine deficiency, rare forms of glycogen storage disease, fatty acid oxidation defects) or persistent myocarditis[]

  • Glucose-6-Phosphate Dehydrogenase Deficiency

    Paul Hochstein, Perspectives on hydrogen peroxide and drug-induced hemolytic anemia in glucose-6-phosphate dehydrogenase deficiency, Free Radical Biology and Medicine, 5,[] In PFK deficiency (glycogen storage disease type VII), clinical hallmarks are male predominance with early onset gout, compensated hemolytic process, and prominent myopathy[] The peripheral blood smear showed polychromasia, anisopoikilocytosis and reticulocytosis (the reticulocyte count was 14.6%). Urine was positive for hemoglobinuria.[]

  • Familial Pseudohyperkalemia

    Neville AJ, Rand CA, Barr RD, Mohan Pai KR: Drug-induced stomatocytosis and anemia during consolidation chemotherapy of childhood acute leukemia.[] 1 - Hyperprolinemia - Sarcosinemia Carbohydrate Lactose intolerance - Glycogen storage disease ( type I , type II , type III, type IV, type V , type VI, type VII ) - fructose[] Her peripheral blood smear revealed polychromasia, target cells, and a few spherocytes.[]

  • Congenital Dyserythropoietic Anemia Type 2

    […] dyserythropoietic anemia , Dilutional anemia , Dimorphic anemia , Drug-induced immune hemolytic anemia , Fanconi anemia, Hemolytic anemia , Idiopathic sideroblastic anemia[] […] other diseases, including congenital megacolon, congenital dyserythropoietic anemia type II, Diamond-Blackfan anemia, Grover disease (transient acantholytic dermatosis), and glycogen-storage[] Fig. 1 Peripheral blood smear showed normochromic, normocytic anemia with increased polychromasia and anisopoikilocytosis including occasional teardrop forms.[]

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