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50 Possible Causes for Drug-induced Hypercalcemia

  • Milk-Alkali Syndrome

    The case described here illustrates the need to consider milk-alkali syndrome in the differential diagnosis of hypercalcemia, even in this age of histamine2 blockers and mucosal protectors. Thorough history taking and gastrointestinal workup help rule out alternative causes of hypercalcemia, such as cancer,[…][ncbi.nlm.nih.gov]

  • Vitamin D Toxicity

    Abstract Ten children age 1 1/2 to 14 years, had bilateral nephrocalcinosis and hypercalciuria, but normal serum calcium (Ca) and phosphate (P) concentrations. Patients with hypercalciuria were divided into absorptive (n 4) and renal (n 6) subgroups, and in the latter four patients had a primary Ca-leak and two had[…][ncbi.nlm.nih.gov]

  • Hypervitaminosis A

    Herein we report a case of liver dysfunction caused by consumption of vitamin A supplements leading to liver transplantation. The patient was a 48-year-old male with a medical history of congenital ichthyosiform erythroderma in treatment with vitamin A until 12 years of age, at which point he discontinued the[…][ncbi.nlm.nih.gov]

  • Pancreatic Abscess

    ., gallstones, constriction of the ampulla of Vater ) 40% of cases Alcohol-induced ( 30% of cases) Idiopathic ( 15%–25% of cases) Other causes Hypertriglyceridemia, hypercalcemia[amboss.com] Post- ERCP Toxic drugs (e.g., steroids, azathioprine, sulfonamides, furosemide, estrogen, protease inhibitors, NRTIs ) Scorpion stings Viral infections (e.g., coxsackievirus[amboss.com]

  • Recurrent Acute Pancreatitis

    ., systemic lupus erythematosus) Choledocholithiasis Chronic alcohol consumption Congenital anomalies Drug-induced hypertriglyceridemia (triglycerides greater than 1,000 mg[aafp.org] […] e.g., pancreas divisum, sphincter of Oddi dysfunction) Autoimmune (e.g., systemic lupus erythematosus) Choledocholithiasis Chronic alcohol consumption Congenital anomalies Drug-induced[aafp.org] […] hypertriglyceridemia (triglycerides greater than 1,000 mg per dL [11.30 mmol per L]) Gallstones Hypercalcemia, hyperparathyroidism Hypothermia Idiopathic Infections (e.g.[aafp.org]

  • Acute Pancreatitis

    , drug-induced, infectious etiologies (eg, mumps, cytomegalovirus), congenital anomalies (pancreas divisum, choledochocele), ampullary or pancreatic tumors, vascular abnormalities[emedicine.com] ., gallstones, constriction of the ampulla of Vater ) 40% of cases Alcohol-induced ( 30% of cases) Idiopathic ( 15%–25% of cases) Other causes Hypertriglyceridemia, hypercalcemia[amboss.com] Other causes include blunt trauma to the abdomen, iatrogenic trauma (postoperative trauma, endoscopic retrograde cholangiopancreatography), hypertriglyceridemia, hypercalcemia[emedicine.com]

  • Dihydrotachysterol

    Calcitonin, cholestyramine, prednisone, sodium EDTA and mithramycin have all been used successfully to treat the more resistant cases of vitamin D-induced hypercalcemia.[syrianclinic.com] Hypocalcemia Adult: PO 0.25 mg/d Renal Osteodystrophy Adult: PO 0.1–0.6 mg/d Child: PO 0.1–0.5 mg/d Oral Withhold drug if signs and symptoms of hypercalcemia appear (see[robholland.com] Drug Interactions Decreased effect/levels of vitamin D: Cholestyramine, colestipol, mineral oil; phenytoin and phenobarbital may inhibit activation and decrease effectiveness[syrianclinic.com]

  • Calcitriol

    Drug: thiazide diuretics may cause hypercalcemia; calcifediol-induced hypercalcemia may precipitate digitalis arrhythmias in patients receiving digitalis glycosides.[robholland.com] Interactions Drug-drug. Antacids containing magnesium: May induce hypermagnesemia, especially in patients with chronic renal failure. Avoid use together.[glowm.com] […] calcitriol dosage may be required 101 Calcium supplements Increased risk of hypercalcemia 101 Avoid uncontrolled intake of additional calcium-containing preparations 101[drugs.com]

  • Vitamin D

    Less frequent causes are granulomatous diseases, drug-induced diseases, and intoxications. Case report.[doi.org] We present two women with life-threatening hypercalcemia due to the intake of vitamin D-concentrated supplements, which turned out to be 100–1,000 times higher than stated[doi.org]

  • Sialadenitis

    Commonly Associated Conditions Postoperative dehydration Radiation-induced xerostomia Drug-induced xerostomia Sjögren syndrome Hypercalcemia -- To view the remaining sections[unboundmedicine.com]

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